KEGG   ENZYME: 1.5.1.2Help
Entry
EC 1.5.1.2                  Enzyme                                 
Name pyrroline-5-carboxylate reductase;
proline oxidase;
L-proline oxidase;
1-pyrroline-5-carboxylate reductase;
NADPH-L-Delta1-pyrroline carboxylic acid reductase;
L-proline-NAD(P)+ 5-oxidoreductase
Class Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname L-proline:NAD(P)+ 5-oxidoreductase
Reaction(IUBMB) L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H + H+
[RN:R01248 R01251]
Reaction(KEGG) R01248 R01251;
(other) R03291 R03293
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Substrate L-proline [CPD:C00148];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product 1-pyrroline-5-carboxylate [CPD:C03912];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment Also reduces 1-pyrroline-3-hydroxy-5-carboxylate to
L-hydroxyproline.
Pathway PATH: ec00330  Arginine and proline metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00286  pyrroline-5-carboxylate reductase
Genes HSA: 29920(PYCR2) 5831(PYCR1) 65263(PYCRL)
PTR: 454977(PYCR1) 472886(PYCRL)
MCC: 697008 709285 715182
MMU: 209027(Pycr1) 66194(Pycrl) 69051(Pycr2)
RNO: 287877(Pycr1) 300035(Pycrl) 364064(Pycr2)
CFA: 480112(PYCR2) 482079(PYCRL) 483372(PYCR1)
BTA: 504987(PYCR2) 512526(PYCRL) 539606(PYCR1)
ECB: 100049879 100054318 100065757
MDO: 100016890 100025433 100025847
OAA: 100079115 100089440
GGA: 420293(PYCRL)
TGU: 100190228(PYCR2)
XLA: 432159
XTR: 548696(TGas136k01.1)
DRE: 100149838 393799(pycr1) 553645 560682(pycrl)
CIN: 100177441 100187490
SPU: 583853
DME: Dmel_CG5840 Dmel_CG6009(P5cr)
DPO: Dpse_GA19170 Dpse_GA19292
DAN: Dana_GF16410 Dana_GF18595
DER: Dere_GG22275 Dere_GG23118
DPE: Dper_GL13575 Dper_GL23580
DSE: Dsec_GM15240 Dsec_GM23296
DSI: Dsim_GD19166
DYA: Dyak_GE25476 Dyak_GE25577
DGR: Dgri_GH13554 Dgri_GH18149
DMO: Dmoj_GI23448 Dmoj_GI24792
AGA: AgaP_AGAP002308 AgaP_AGAP005009
AAG: AaeL_AAEL007033 AaeL_AAEL008418 AaeL_AAEL009831
CQU: CpipJ_CPIJ000123 CpipJ_CPIJ005082 CpipJ_CPIJ012704
AME: 408859 412234
NVI: 100115621 100122100
TCA: 663628 663647 664343
API: 100161005(Acypi002263)
ISC: IscW_ISCW020302
CEL: F55G1.9 M153.1
CBR: CBG05881 CBG16221
BMY: Bm1_38015
SMM: Smp_049390
NVE: NEMVE_v1g112837 NEMVE_v1g160797 NEMVE_v1g235823
HMG: 100205698 100213852
TAD: TRIADDRAFT_27568
ATH: AT5G14800(P5CR)
POP: POPTR_831811
RCU: RCOM_1107270
VVI: 100258887(GSVIVT00000690001)
OSA: 4325755(Os01g0948400)
SBI: SORBI_03g045690(SORBIDRAFT_03g045690)
ZMA: 100274455 606449(p5cr)
PPP: PHYPADRAFT_138353
OLU: OSTLU_13156
CME: CMH137C CMI158C
SCE: YER023W(PRO3)
AGO: AGOS_ABR168W
KLA: KLLA0D10736g
LTH: KLTH0F18282g
DHA: DEHA0F06754g
PIC: PICST_35750(PRO3)
PPA: PAS_chr4_0398
VPO: Kpol_1013p58
LEL: LELG_04301
ZRO: ZYRO0D01782g
CTP: CTRG_00127
CDU: CD36_40310
CGR: CAGL0I08283g
YLI: YALI0B14399g
SPO: SPAPYUG7.05
NCR: NCU06471
PAN: PODANSg5401
MGR: MGG_02349 MGG_06376
FGR: FG03075.1 FG03917.1 FG07255.1
ANI: AN4355.2 AN6025.2 AN7387.2 AN9279.2
AFM: AFUA_3G02310 AFUA_5G14770
AOR: AO090005000035 AO090012000119 AO090120000046 AO090206000124
ANG: An01g01520 An04g02800 An07g05050
AFV: AFLA_014050 AFLA_072750 AFLA_090440 AFLA_114290
PCS: Pc12g13680 Pc16g08760 Pc22g23710
NFI: NFIA_003470 NFIA_072200
CIM: CIMG_05390
URE: UREG_06322
SSL: SS1G_03681 SS1G_09630 SS1G_10564
BFU: BC1G_03527 BC1G_10623
CNE: CNF00740
CNB: CNBF3820
LBC: LACBIDRAFT_291005
UMA: UM00547.1
MGL: MGL_1063
PFA: MAL13P1.284
PFD: PFDG_00683
PFH: PFHG_04440
PYO: PY02938
PCB: PC001209.02.0
PBE: PB001079.00.0 PB300754.00.0
PKN: PKH_111310
PVX: PVX_114870
CPV: cgd6_3720
CHO: Chro.60426
TGO: TGME49_036070
TET: TTHERM_00107210
TBR: Tb927.7.2440
TCR: 506857.20 509207.90
LMA: LmjF13.1680
LIF: LinJ03.0630
LBZ: LbrM13_V2.1540
TVA: TVAG_063510 TVAG_423640
PTI: PHATRDRAFT_25379
TPS: THAPSDRAFT_23275 THAPS_6798
ECO: b0386(proC)
ECJ: JW0377(proC)
ECD: ECDH10B_0343(proC)
EBW: BWG_0270(proC)
ECE: Z0482(proC)
ECS: ECs0437(proC)
ECF: ECH74115_0460(proC)
ETW: ECSP_0448(proC)
ECG: E2348C_0322(proC)
ECC: c0493(proC)
ECI: UTI89_C0405(proC)
ECP: ECP_0445
ECV: APECO1_1622(proC)
ECW: EcE24377A_0413(proC)
ECX: EcHS_A0454(proC)
ECM: EcSMS35_0416(proC)
ECY: ECSE_0407
ECL: EcolC_3246
ECK: EC55989_0395(proC)
ECQ: ECED1_0409(proC)
ECR: ECIAI1_0386(proC)
ECT: ECIAI39_0295(proC)
ECZ: ECS88_0381(proC)
EUM: ECUMN_0424(proC)
ELF: LF82_1728(proC)
EBL: B21_00337(proC)
EBD: ECBD_3278
EBR: ECB_00333(proC)
EOH: ECO103_0361(proC)
EOI: ECO111_0416(proC)
EOJ: ECO26_0419(proC)
EFE: EFER_2637(proC)
STY: STY0419(proC)
STT: t2478(proC)
SPT: SPA2337(proC)
SEK: SSPA2180
SPQ: SPAB_03204
SEI: SPC_0396(proC)
SEC: SC0427(proC)
SEH: SeHA_C0483(proC)
SEE: SNSL254_A0428(proC)
SEW: SeSA_A0441(proC)
SEA: SeAg_B0422(proC)
SED: SeD_A0423(proC)
SEG: SG0398(proC)
SET: SEN0369(proC)
SES: SARI_02540
STM: STM0386(proC)
YPE: YPO0942(proC)
YPK: y3328(proC)
YPM: YP_3500(proC)
YPA: YPA_0323
YPN: YPN_3139
YPG: YpAngola_A0139(proC)
YPP: YPDSF_0573
YPS: YPTB3214(proC)
YPI: YpsIP31758_0829(proC)
YPY: YPK_0831
YPB: YPTS_3347
YEN: YE3434(proC)
SFL: SF0322(proC)
SFX: S0330(proC)
SFV: SFV_0351(proC)
SSN: SSON_0362(proC)
SBO: SBO_0282(proC)
SBC: SbBS512_E0303(proC)
SDY: SDY_0356(proC)
ECA: ECA3628(proC)
PCT: PC1_3451
PWA: Pecwa_3608
ETA: ETA_25660(proC)
PLU: plu1179(proC)
PAY: PAU_03281
WBR: WGLp079(proC)
SGL: SG2028
ENT: Ent638_0857 Ent638_1870
ESA: ESA_02919
CTU: Ctu_09600(proC)
KPN: KPN_00329(proC)
KPE: KPK_1534 KPK_4357(proC)
KPU: KP1_1188(proC)
CKO: CKO_02785
SPE: Spro_4031
PMR: PMI0335(proC)
EIC: NT01EI_3773
ETR: ETAE_3400(proC)
HDE: HDEF_0483(proC)
DDA: Dd703_0774 Dd703_1833
DDC: Dd586_2913 Dd586_3392
DZE: Dd1591_0759
HIN: HI0307(proC)
HIT: NTHI0426(proC)
HIP: CGSHiEE_01515
HIQ: CGSHiGG_04350
HAP: HAPS_0803(proC)
HSO: HS_1285(proC)
HSM: HSM_0333
PMU: PM0095(proC)
MSU: MS1799(proC)
APL: APL_0160(proC)
APJ: APJL_0161
APA: APP7_0162
ASU: Asuc_1764
AAP: NT05HA_0132
AAT: D11S_1932 D11S_1933
XFA: XF2712
XFT: PD2064(proC)
XFM: Xfasm12_2260
XFN: XfasM23_2167
XCC: XCC2757(proC)
XCB: XC_1356
XCA: xccb100_1404
XCV: XCV3070(proC)
XAC: XAC2926(proC)
XOO: XOO1416(proC)
XOM: XOO_1300
XOP: PXO_01991(proC)
SML: Smlt1087
SMT: Smal_0929
VCH: VC0460
VCO: VC0395_A0012(proC)
VCM: VCM66_0445(proC)
VCJ: VCD_001147
VVU: VV1_1524
VVY: VV2875
VPA: VP2617
VHA: VIBHAR_03579
VSP: VS_2684
VEX: VEA_002455
VFI: VF_0429(proC)
VFM: VFMJ11_0429(proC)
VSA: VSAL_I0542(proC)
PPR: PBPRA3144
PAE: PA0393(proC)
PAU: PA14_05150(proC)
PAP: PSPA7_0493(proC)
PAG: PLES_03911(proC)
PPU: PP_5095(proC-2)
PPF: Pput_4968
PPG: PputGB1_5145
PPW: PputW619_0370
PST: PSPTO_5047(proC)
PSB: Psyr_0476
PSP: PSPPH_0467(proC)
PFL: PFL_5839(proC)
PFO: Pfl01_5320
PFS: PFLU5764
PEN: PSEEN0317(proC)
PMY: Pmen_4151
PSA: PST_3967(proC)
CJA: CJA_0089(proC)
AVN: Avin_03070(proC)
PAR: Psyc_0165(proC)
PCR: Pcryo_0177
PRW: PsycPRwf_0337
ACI: ACIAD3032(proC)
ACB: A1S_0610 A1S_1229
ABM: ABSDF2899(proC)
ABY: ABAYE2533 ABAYE3151(proC)
ABC: ACICU_00614 ACICU_01212
ABN: AB57_0713(proC) AB57_1369
ABB: ABBFA_002344 ABBFA_002951(proC)
SON: SO_3354(proC)
SDN: Sden_2683
SFR: Sfri_0761 Sfri_2861
SAZ: Sama_2478
SBL: Sbal_3026
SBM: Shew185_3041
SBN: Sbal195_3184
SBP: Sbal223_1337
SLO: Shew_1136 Shew_3016
SPC: Sputcn32_2688
SSE: Ssed_1231
SPL: Spea_1126
SHE: Shewmr4_1192
SHM: Shewmr7_1263
SHN: Shewana3_1193
SHW: Sputw3181_1323
SHL: Shal_1171
SWD: Swoo_1331
SWP: swp_3674
ILO: IL1975(proC)
CPS: CPS_3664(proC)
PHA: PSHAa2605(proC)
PAT: Patl_3719
SDE: Sde_3642
MAQ: Maqu_0535
AMC: MADE_03299
PIN: Ping_3041
TTU: TERTU_0222(proC)
CBU: CBU_2090(proC)
CBS: COXBURSA331_A2215(proC)
CBD: CBUD_2189(proC)
CBG: CbuG_2092(proC)
CBC: CbuK_2140(proC)
LPN: lpg2015(proC)
LPF: lpl1992(proC)
LPP: lpp1997(proC)
LPC: LPC_1499(proC)
MCA: MCA1535(proC)
FTU: FTT_1559c(proC)
FTF: FTF1559c(proC)
FTW: FTW_0368(proC)
FTL: FTL_0549
FTH: FTH_0551(proC)
FTA: FTA_0582(proC)
FTM: FTM_0340(proC)
FTN: FTN_1467(proC)
FPH: Fphi_1208
TCX: Tcr_1837
NOC: Noc_3002
AEH: Mlg_0340
HHA: Hhal_0946
TGR: Tgr7_2920
HNA: Hneap_1839
HCH: HCH_06354(proC)
CSA: Csal_3055
ABO: ABO_2668(proC)
MMW: Mmwyl1_0546
AHA: AHA_3663(proC)
ASA: ASA_3630(proC)
TAU: Tola_0964
DNO: DNO_0674(proC)
AFE: Lferr_0439
AFR: AFE_0262(proC)
RMA: Rmag_0116
VOK: COSY_0121(proC)
KKO: Kkor_0216
NMA: NMA0215
NME: NMB0055(proC)
NMC: NMC0039(proC)
NMN: NMCC_0055(proC)
NMI: NMO_1954(proC)
NGO: NGO1905
NGK: NGK_2352
CVI: CV_0177(proC)
LHK: LHK_00034(proC)
RSO: RSc2684(proC)
RPI: Rpic_2920
RPF: Rpic12D_2508
REU: Reut_A2802
REH: H16_A3106(proC)
RME: Rmet_2938
CTI: RALTA_A2581(proC)
BMA: BMA2410(proC)
BMV: BMASAVP1_A0327(proC)
BML: BMA10229_A1188(proC)
BMN: BMA10247_2597(proC)
BPS: BPSL2847
BPM: BURPS1710b_3347(proC)
BPL: BURPS1106A_3334(proC)
BPD: BURPS668_3300(proC)
BPR: GBP346_A3478(proC)
BTE: BTH_I1287(proC)
BVI: Bcep1808_0691
BUR: Bcep18194_A3816
BCN: Bcen_0246
BCH: Bcen2424_0730
BCM: Bcenmc03_0698
BCJ: BCAL3292
BAM: Bamb_0620
BAC: BamMC406_0646
BMU: Bmul_2656
BMJ: BMULJ_00582(proC)
BXE: Bxe_A3982 Bxe_B1422
BPH: Bphy_2518 Bphy_6863
BPY: Bphyt_0716
BGL: bglu_1g06130
PNU: Pnuc_1785
PNE: Pnec_1502
BPE: BP1280(proC)
BPA: BPP1311(proC) BPP2943(proC)
BBR: BB2376(proC) BB2911(proC)
BPT: Bpet2320(proC)
BAV: BAV1898(proC)
RFR: Rfer_3679
POL: Bpro_0475
PNA: Pnap_0327
AAV: Aave_0601
AJS: Ajs_0381
VEI: Veis_2325
DAC: Daci_1017
DIA: Dtpsy_0372
VAP: Vapar_5062
CTT: CtCNB1_4451
MPT: Mpe_A3746
HAR: HEAR0291(proC)
MMS: mma_0342(proC)
LCH: Lcho_1627
NEU: NE0393(proC)
NET: Neut_2148
NMU: Nmul_A0581
EBA: ebA1766(proC)
AZO: azo3466(proC)
DAR: Daro_3885
TBD: Tbd_2417
MFA: Mfla_2109
MMB: Mmol_0630
MEI: Msip34_0621
APP: CAP2UW1_3599
HPY: HP1158
HPJ: jhp1085(proC)
HPA: HPAG1_1097
HPS: HPSH_05975
HPG: HPG27_1102
HPP: HPP12_1124(proC)
HPB: HELPY_1132(proC)
HHE: HH0842(proC)
HAC: Hac_1325(proC)
WSU: WS1975(proC)
TDN: Suden_0791
CJE: Cj1076(proC)
CJR: CJE1219(proC)
CJJ: CJJ81176_1094(proC)
CJU: C8J_1017(proC)
CJD: JJD26997_0647(proC)
CFF: CFF8240_1569
CCV: CCV52592_0752(proC)
CHA: CHAB381_0551(proC)
CLA: Cla_0958(proC)
ABU: Abu_0590(proC)
SDL: Sdel_1723
NIS: NIS_1350(proC)
SUN: SUN_1761(proC)
NAM: NAMH_0834(proC)
GSU: GSU2541(proC)
GME: Gmet_0899
GUR: Gura_0979
GLO: Glov_3093
GBM: Gbem_3383
GEO: Geob_1674
GEM: GM21_0863
PCA: Pcar_0397(proC)
PPD: Ppro_2828
DVU: DVU2332(proC)
DVL: Dvul_0926
DVM: DvMF_3161
DDE: Dde_1440
DDS: Ddes_0893
DMA: DMR_17060(proC)
DSA: Desal_1615
LIP: LI1120(proC)
DBA: Dbac_2889
DRT: Dret_2165
BBA: Bd0465(proC)
DPS: DP2233
DOL: Dole_0129
DAL: Dalk_3462
DAT: HRM2_40670(proC)
ADE: Adeh_2480
ACP: A2cp1_1474
AFW: Anae109_1387
ANK: AnaeK_1378
SCL: sce5868(proC)
HOH: Hoch_4718
SAT: SYN_02197
SFU: Sfum_0197
ERU: Erum0030(proC)
ERW: ERWE_CDS_09480(proC)
ERG: ERGA_CDS_09400(proC)
ECN: Ecaj_0941
ECH: ECH_0013
PUB: SAR11_1353
MLO: mll6498
MES: Meso_0151
PLA: Plav_2265
SME: SM_b20003 SMc02677(proC)
SMD: Smed_2249 Smed_4127 Smed_5474
ATU: Atu2209(proC)
ATC: AGR_C_4015
ARA: Arad_12144(proC) Arad_3173(proC) Arad_8082
AVI: Avi_3168(proC) Avi_9249(proC)
RET: RHE_CH03015(proC) RHE_PF00430(ypf00230)
REC: RHECIAT_CH0003173(proC) RHECIAT_PC0000654
RLE: RL3460(proC) pRL120421(proC)
RLT: Rleg2_2755 Rleg2_4835
RLG: Rleg_3018 Rleg_4785
RHI: NGR_c22890(proC2) NGR_c30250(proC1)
BME: BMEII0509
BMI: BMEA_B0760(proC)
BMF: BAB2_0456(proC)
BMB: BruAb2_0450(proC)
BMC: BAbS19_II04310
BMS: BRA0782(proC)
BMT: BSUIS_B0774(proC)
BOV: BOV_A0732(proC)
BCS: BCAN_B0795(proC)
BMR: BMI_II775(proC)
OAN: Oant_3963
BJA: blr7454(proC)
BRA: BRADO6035(proC)
BBT: BBta_1743(proC)
RPA: RPA4366(proC)
RPB: RPB_4171
RPC: RPC_1406
RPD: RPD_3882
RPE: RPE_1427
RPT: Rpal_4850
NWI: Nwi_2514
NHA: Nham_3106
OCA: OCAR_7200(proC)
BHE: BH12330(proC)
BQU: BQ09700(proC)
BBK: BARBAKC583_1041
BTR: Btr_1884(proC)
BGR: Bgr_09420(proC)
XAU: Xaut_2538
AZC: AZC_3979
MEX: Mext_3769
MEA: Mex_1p4140(proC)
MDI: METDI4732(proC)
MRD: Mrad2831_4946
MET: M446_0881
MPO: Mpop_4024
MCH: Mchl_4063
MNO: Mnod_1362 Mnod_8008
BID: Bind_1258
MSL: Msil_1138
CCR: CC_0494
CCS: CCNA_00528
CAK: Caul_0677
PZU: PHZ_c2855(proC)
SIL: SPO0911(proC)
SIT: TM1040_0623
RSP: RSP_3364(proC)
RSH: Rsph17029_3009
RSQ: Rsph17025_1323
RSK: RSKD131_3527
JAN: Jann_3328
RDE: RD1_2848 RD1_3497(proC)
PDE: Pden_2198 Pden_4871
DSH: Dshi_2645(proC)
MMR: Mmar10_0764 Mmar10_2668
HNE: HNE_1387(proC)
HBA: Hbal_0311
ZMO: ZMO0311 ZMO1303
ZMN: Za10_0047 Za10_0918
NAR: Saro_1142
SAL: Sala_0045
SWI: Swit_4472
ELI: ELI_01840
GOX: GOX1131
GBE: GbCGDNIH1_2307
ACR: Acry_2704
GDI: GDI_0925(proC)
GDJ: Gdia_1097
APT: APA01_26410
RRU: Rru_A3281
RCE: RC1_1898(proC)
MAG: amb0545
MGM: Mmc1_3656
BSU: BSU12910(proG) BSU18480(proH) BSU23800(proI)
BHA: BH0887 BH1503
BAN: BA0197 BA2995(proC) BA3143(proC) BA4359(proC-3)
BAR: GBAA0197 GBAA2995(proC) GBAA3143(proC) GBAA4359(proC-3)
BAA: BA_0778 BA_3501 BA_3644 BA_4817
BAT: BAS0198 BAS2783(proC) BAS2921(proC) BAS4045
BAH: BAMEG_0231 BAMEG_1610(proC1) BAMEG_4399(proC3)
BAI: BAA_3048(proC1) BAA_3190(proC2) BAA_4381(proC3)
BCE: BC0218 BC2977(proC) BC3109(proC) BC4134
BCA: BCE_0217 BCE_3031(proC) BCE_4207(proC)
BCZ: BCZK0188(proC) BCZK2713(proC) BCZK2850(proC) BCZK3891(proC)
BCR: BCAH187_A0240 BCAH187_A3029(proC1) BCAH187_A3164(proC2)
     BCAH187_A4270(proC3)
BCB: BCB4264_A0223 BCB4264_A2995(proC1) BCB4264_A3132(proC2)
     BCB4264_A4246(proC3)
BCU: BCAH820_0217 BCAH820_2991(proC1) BCAH820_3154(proC2)
     BCAH820_4160(proC3)
BCG: BCG9842_B0990(proC3) BCG9842_B2250(proC1) BCG9842_B5103
BCQ: BCQ_0220(proC) BCQ_2811(proC) BCQ_2949(proC) BCQ_3926(proC)
BCX: BCA_0243 BCA_3065(proC1) BCA_4249(proC3)
BCY: Bcer98_0197 Bcer98_2833
BTK: BT9727_0185(proC) BT9727_2732(proC) BT9727_2899(proC)
     BT9727_3883(proC)
BTL: BALH_0197(proC) BALH_2680(proC) BALH_2813(proC) BALH_3751(proC)
BWE: BcerKBAB4_0182 BcerKBAB4_2791 BcerKBAB4_3969
BLI: BL00796(proI) BL01982(proH) BL03773(proG)
BLD: BLi01391(proG) BLi02150(proH) BLi02549(proI)
BCL: ABC1247 ABC1765(proI)
BAY: RBAM_018650(proH) RBAM_021930(proI)
BPU: BPUM_1183(proC) BPUM_1824(proH) BPUM_2109(proI)
OIH: OB0013
GKA: GK2331
GTN: GTNG_2261
GWC: GWCH70_2273
GYM: GYMC10_2268
GYC: GYMC61_0351
AFL: Aflv_0982(proI)
SAU: SA1334
SAV: SAV1503
SAW: SAHV_1491
SAM: MW1457
SAR: SAR1579
SAS: SAS1443
SAC: SACOL1546(proC)
SAB: SAB1364
SAA: SAUSA300_1452(proC)
SAX: USA300HOU_1504
SAO: SAOUHSC_01597
SAJ: SaurJH9_1560
SAH: SaurJH1_1591
SAE: NWMN_1410
SAD: SAAV_1493
SEP: SE1186
SER: SERP1065(proC)
SHA: SH1413
SSP: SSP1250
SCA: Sca_1128
LMO: lmo0396(proC) lmo1387
LMF: LMOf2365_0408(proC) LMOf2365_1406
LMH: LMHCC_1182 LMHCC_2240(proC)
LMC: Lm4b_00414 Lm4b_01396
LIN: lin0414(proC) lin1424
LWE: lwe0344(proC) lwe1403
LSP: Bsph_3416(yqjO) Bsph_3417
ESI: Exig_2898
EAT: EAT1b_2295
MCL: MCCL_1152
BBE: BBR47_10480(proG) BBR47_49060(proC)
PJD: Pjdr2_2466
AAC: Aaci_2581
LLA: L135991(proC)
LLK: LLKF_2077(proC)
LLC: LACR_2080
LLM: llmg_2077(proC)
SPY: SPy_0112(proC)
SPZ: M5005_Spy_0096(proC)
SPM: spyM18_0113
SPG: SpyM3_0088(proC)
SPS: SPs0089
SPH: MGAS10270_Spy0098(proC)
SPI: MGAS10750_Spy0103(proC)
SPJ: MGAS2096_Spy0099(proC)
SPK: MGAS9429_Spy0097(proC)
SPF: SpyM50094(proC)
SPA: M6_Spy0144
SPB: M28_Spy0094(proC)
SOZ: Spy49_0100(proC)
SPN: SP_0933
SPD: SPD_0824(proC)
SPR: spr0834(proC)
SPW: SPCG_0908(proC)
SPX: SPG_0860(proC)
SNE: SPN23F_08560(proC)
SPV: SPH_1042(proC)
SNM: SP70585_0972(proC)
SJJ: SPJ_0873(proC)
SPP: SPP_0940(proC)
SNT: SPT_1266(proC)
SAG: SAG0173(proC)
SAN: gbs0171
SAK: SAK_0239(proC)
SMU: SMU.1974(proC)
STC: str1852(proC)
STL: stu1852(proC)
STE: STER_1828
SSA: SSA_1074(proC)
SSU: SSU05_0559
SSV: SSU98_0560
SSB: SSUBM407_1303(proC)
SSI: SSU0510(proC)
SSS: SSUSC84_0495(proC)
SGO: SGO_1099(proC)
SEQ: SZO_18490
SEZ: Sez_1850(proC)
SEU: SEQ_2135
SUB: SUB0130(proC)
SDS: SDEG_0146(proC)
LPL: lp_0561(proC)
LPJ: JDM1_0458(proC)
LAC: LBA1116
LSA: LSA1590(proC)
LSL: LSL_1264(proC)
LBR: LVIS_0538
LCA: LSEI_1809
LCB: LCABL_20290(proC)
LRE: Lreu_0033 Lreu_0344
LRF: LAR_0032 LAR_0333
LFE: LAF_1394
LRH: LGG_01863(proC)
LRL: LC705_01845(proC)
EFA: EF0961 EF2424
OOE: OEOE_0946
LME: LEUM_1864
LCI: LCK_01504(proC)
CAC: CAC3252(proC)
CPE: CPE2633(proC)
CPF: CPF_2969(proC)
CPR: CPR_2647(proC)
CTC: CTC02431(proC)
CNO: NT01CX_0903(proC)
CTH: Cthe_0672
CDF: CD1495(proC1) CD3281(proC2)
CDC: CD196_1368(proC1) CD196_3096(proC2)
CDL: CDR20291_1345(proC1) CDR20291_3142(proC2)
CBO: CBO3182(proC)
CBA: CLB_3218(proC)
CBH: CLC_3092(proC)
CBY: CLM_3594(proC)
CBL: CLK_2580(proC)
CBK: CLL_A3578(proC)
CBB: CLD_1349(proC)
CBI: CLJ_B3454(proC)
CBT: CLH_3372(proC)
CBF: CLI_3321(proC)
CBE: Cbei_5077
CKL: CKL_0326(proC1) CKL_2737(proC2)
CKR: CKR_0278 CKR_2431
CPY: Cphy_2914 Cphy_3151
CCE: Ccel_1755
AMT: Amet_2533
AOE: Clos_0129
STH: STH1086
SWO: Swol_0955
VPR: Vpar_1429
ATE: Athe_1339
DSY: DSY1385
DHD: Dhaf_2500
DRM: Dred_1168
DAE: Dtox_1084
PTH: PTH_1826(proC)
DAU: Daud_1412
HMO: HM1_2091(proC)
EEL: EUBELI_01117
ERE: EUBREC_1178
TTE: TTE1361(proC)
TEX: Teth514_1615
TPD: Teth39_1178
CHY: CHY_2041(proC)
MTA: Moth_0860
ADG: Adeg_1017
CSC: Csac_1902
HOR: Hore_01940
MFL: Mfl045
MTU: Rv0500(proC)
MTC: MT0520(proC)
MRA: MRA_0507(proC)
MTF: TBFG_10509
MTB: TBMG_00505(TBMG_00505.1)
MBO: Mb0511(proC)
MBB: BCG_0542(proC)
MBT: JTY_0512(proC)
MLE: ML2430(proC)
MLB: MLBr_02430(proC)
MPA: MAP3991(proC)
MAV: MAV_4652(proC)
MSM: MSMEG_0943(proC)
MUL: MUL_4570(proC)
MVA: Mvan_0837
MGI: Mflv_0075
MAB: MAB_4005c
MMC: Mmcs_0668
MKM: Mkms_0681
MJL: Mjls_0661
MMI: MMAR_0826(proC)
CGL: NCgl0398(cgl0410)
CGB: cg0490(proC)
CGT: cgR_0483
CEF: CE0430(proC)
CDI: DIP0394(proC)
CJK: jk1906(proC)
CUR: cur_0219
CAR: cauri_0291(proC)
CKP: ckrop_1917
NFA: nfa51770(proC)
RHA: RHA1_ro02061
RER: RER_16330(proC)
ROP: ROP_17320(proC)
GBR: Gbro_1003
SCO: SCO3337(proC)
SMA: SAV_4724(proC)
SGR: SGR_4141
TWH: TWT752(proC)
TWS: TW764(proC)
LXX: Lxx01720(proC)
CMI: CMM_0544(proC)
CMS: CMS_2550(proC)
ART: Arth_3348
AAU: AAur_3330(proC)
ACH: Achl_3146
RSA: RSal33209_2727
KRH: KRH_04770(proC)
MLU: Mlut_18050
BCV: Bcav_3276
BFA: Bfae_24360
JDE: Jden_0968
KSE: Ksed_24470
XCE: Xcel_0399
PAC: PPA0319
NCA: Noca_0481
TFU: Tfu_2708
TCU: Tcur_4459
SRO: Sros_0533
FRA: Francci3_0476
FRE: Franean1_6140
FAL: FRAAL0974(proC)
ACE: Acel_0247
NML: Namu_0898
KRA: Krad_0610
SEN: SACE_6959(proC)
SVI: Svir_02750
AMI: Amir_6743
STP: Strop_3266
SAQ: Sare_3496
CAI: Caci_8353
BLO: BL0927(proC)
BLJ: BLD_0668(proC)
BLN: Blon_0751 Blon_1690
BAD: BAD_0608(proC)
BLA: BLA_0993(proC)
BLC: Balac_1054
BLT: Balat_1054
RXY: Rxyl_1485
AFO: Afer_0357
SHI: Shel_16300
ELE: Elen_2285
PCU: pc1132(proC)
TPP: TPASS_0797(proC)
LIL: LA1481(proC)
LIC: LIC12275(proC)
LBJ: LBJ_0981(proC)
LBL: LBL_2052(proC)
LBI: LEPBI_I1336(proC)
LBF: LBF_1282(proC)
BHY: BHWA1_00689(proC)
ABA: Acid345_1478
ACA: ACP_1238(proC)
BTH: BT_1902 BT_3757
BFR: BF0530
BFS: BF0478
BVU: BVU_0589
PDI: BDI_2250
APS: CFPG_324
SRU: SRU_1560(proC)
RMR: Rmar_1570
CHU: CHU_0937(proC)
DFE: Dfer_3513
CPI: Cpin_0657
PHE: Phep_4204
GFO: GFO_1961(proC) GFO_2105
FJO: Fjoh_0842
FPS: FP0066(proC)
RBI: RB2501_08695 RB2501_13499
FSU: Fisuc_2427
LBA: Lebu_1569
STR: Sterm_2788
OTE: Oter_3795
MIN: Minf_0186(proC)
AMU: Amuc_1990
GAU: GAU_3259(proC)
RBA: RB3891(proC)
EMI: Emin_1383
TAI: Taci_0568
SYN: slr0661(proC)
SYW: SYNW0662(proC)
SYC: syc2035_d(proC)
SYF: Synpcc7942_2058
SYD: Syncc9605_2023
SYE: Syncc9902_0649
SYG: sync_0601(proC)
SYR: SynRCC307_0471(proC)
SYX: SynWH7803_0573(proC)
SYP: SYNPCC7002_A1919(proC)
CYA: CYA_0863(proC)
CYB: CYB_1749(proC)
TEL: tlr1217(proC)
MAR: MAE_55900(proC)
CYT: cce_2615(proC)
CYP: PCC8801_1696
CYC: PCC7424_0548
CYN: Cyan7425_1472
CYH: Cyan8802_1715
GVI: glr0704
ANA: alr0488
NPU: Npun_F2187 Npun_R1697
AVA: Ava_1616 Ava_2901
PMA: Pro0393(proC)
PMM: PMM0396(proC)
PMT: PMT0208(proC)
PMN: PMN2A_1731
PMI: PMT9312_0392
PMB: A9601_04471(proC)
PMC: P9515_04581(proC)
PMF: P9303_21461(proC)
PMG: P9301_04161(proC)
PMH: P9215_04731(proC)
PMJ: P9211_03931
PME: NATL1_04481(proC)
TER: Tery_4908
AMR: AM1_5367(proC)
CTE: CT0077(proC)
CPC: Cpar_1985
CCH: Cag_1680
CPH: Cpha266_2466
CPB: Cphamn1_2357
CLI: Clim_2306
PVI: Cvib_0217
PLT: Plut_0150
PPH: Ppha_0212
PAA: Paes_2120
CTS: Ctha_2593
DET: DET0193(proC)
DEH: cbdb_A200(proC)
DEB: DehaBAV1_0160
DEV: DhcVS_181
RRS: RoseRS_0390
RCA: Rcas_1154
CAU: Caur_2241
CAG: Cagg_2947
CHL: Chy400_2414
HAU: Haur_3564
TRO: trd_A0856(proC)
DRA: DR_1522
DGE: Dgeo_0841
DDR: Deide_13780
TTH: TTC0500
TTJ: TTHA0852
AAE: aq_166(proC)
HYA: HY04AAS1_0780
SUL: SYO3AOP1_1439
SAF: SULAZ_1638(proC)
PMX: PERMA_0589(proC)
TMA: TM0578
TPT: Tpet_0340
TLE: Tlet_1873
TRQ: TRQ2_0358
TNA: CTN_0087
TNP: Tnap_0360
PMO: Pmob_0218
KOL: Kole_1107
DTH: DICTH_0191 DICTH_1188(proC)
DTU: Dtur_1304
TYE: THEYE_A1799(proC)
TTR: Tter_1437
MAC: MA4102(proC)
MBA: Mbar_A0480
MMA: MM_0817
MBU: Mbur_2111
MEM: Memar_1294
MST: Msp_1314(proC)
MSI: Msm_0089
HWA: HQ1846A(proC)
NPH: NP3974A(proC)
HUT: Huta_1373
HMU: Hmuk_3392
TAC: Ta0139
TVO: TVN1139
PTO: PTO1416
PFU: PF1715
TKO: TK0272 TK0273
TON: TON_0888
TGA: TGAM_1616(proC)
TSI: TSIB_0621
APE: APE_0146.1
IHO: Igni_0659
HBU: Hbut_0328
SSO: SSO0495(proC)
STO: ST0646
SIS: LS215_1739
SIA: M1425_1612
SIM: M1627_1727
SID: M164_1659
SIY: YG5714_1703
SIN: YN1551_1200
MSE: Msed_0977
PAI: PAE1917
PIS: Pisl_1767
PCL: Pcal_0881
PAS: Pars_2117
CMA: Cmaq_0974
TNE: Tneu_0782
TPE: Tpen_1839
KCR: Kcr_0735
Taxonomy
Structures PDB: 2AHR  2GER  2GR9  2GRA  2IZZ  2RCY  3GT0  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:13681369]
ADAMS E, GOLDSTONE A.
Hydroxyproline metabolism. III. Enzymatic synthesis of
hydroxyproline from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
J. Biol. Chem. 235 (1960) 3499-503.
Neurospora crassa [GN:ncr]
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:13502341]
MEISTER A, RADHAKRISHNAN AN, BUCKLEY SD.
Enzymatic synthesis of L-pipecolic acid and L-proline.
J. Biol. Chem. 229 (1957) 789-800.
Rattus norvegicus [GN:rno]
Reference
  Authors
  Title

  Journal
 3  [PMID:13334497]
SMITH ME, GREENBERG DM.
Characterization of an enzyme reducing pyrroline-5-carboxylate to
proline.
Nature. 177 (1956) 1130.
Reference
  Authors
  Title

  Journal
  Organism
 4  [PMID:13630905]
YURA T, VOGEL HJ.
Pyrroline-5-carboxylate reductase of Neurospora crassa; partial
purification and some properties.
J. Biol. Chem. 234 (1959) 335-8.
Neurospora crassa [GN:ncr]
Other DBs ExplorEnz - The Enzyme Database: 1.5.1.2
IUBMB Enzyme Nomenclature: 1.5.1.2
ExPASy - ENZYME nomenclature database: 1.5.1.2
BRENDA, the Enzyme Database: 1.5.1.2
CAS: 9029-17-8
DBGET integrated database retrieval system