| Entry |
|
|---|
| Name |
methylglutamate dehydrogenase;
N-methylglutamate dehydrogenase;
N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating) |
|---|
| Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With other acceptors
 |
|---|
| Sysname |
N-methyl-L-glutamate:acceptor oxidoreductase (demethylating) |
|---|
| Reaction(IUBMB) |
N-methyl-L-glutamate + acceptor + H2O = L-glutamate + formaldehyde +
reduced acceptor [RN:R00609] |
|---|
| Reaction(KEGG) |
R00609
 |
|---|
| Substrate |
N-methyl-L-glutamate [CPD:C01046];
acceptor [CPD:C00028];
H2O [CPD:C00001] |
|---|
| Product |
L-glutamate [CPD:C00025];
formaldehyde [CPD:C00067];
reduced acceptor [CPD:C00030] |
|---|
| Comment |
A number of N-methyl-substituted amino acids can act as donor;
2,6-dichloroindophenol is the best acceptor. |
|---|
| Pathway |
PATH: ec00680 Methane metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5028076]
Hersh LB, Stark MJ, Worthen S, Fiero MK.
N-methylglutamate dehydrogenase: kinetic studies on the solubilized
enzyme.
Arch. Biochem. Biophys. 150 (1972) 219-26.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.5.99.5
IUBMB Enzyme Nomenclature: 1.5.99.5
ExPASy - ENZYME nomenclature database: 1.5.99.5
BRENDA, the Enzyme Database: 1.5.99.5
CAS: 37217-26-8 |
|---|
