| Entry |
|
|---|
| Name |
nitrate reductase [NAD(P)H];
assimilatory nitrate reductase;
assimilatory NAD(P)H-nitrate reductase;
NAD(P)H bispecific nitrate reductase;
nitrate reductase (reduced nicotinamide adenine dinucleotide
(phosphate));
nitrate reductase NAD(P)H;
NAD(P)H-nitrate reductase;
nitrate reductase [NAD(P)H2];
NAD(P)H2:nitrate oxidoreductase |
|---|
| Class |
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
nitrite:NAD(P)+ oxidoreductase |
|---|
| Reaction(IUBMB) |
nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ [RN:R00794 R00796] |
|---|
| Reaction(KEGG) |
R00794 R00796
 |
|---|
| Substrate |
nitrite [CPD:C00088];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Product |
nitrate [CPD:C00244];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Cofactor |
FAD [CPD:C00016];
FMN [CPD:C00061] |
|---|
| Comment |
An iron-sulfur molybdenum flavoprotein. |
|---|
| Pathway |
PATH: ec00910 Nitrogen metabolism |
|---|
| Structures |
PDB: 2BIH 2BII |
|---|
Reference
Authors
Title
Journal
|
1
Nason, A.
Nitrate reductases.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 7, Academic Press, New York, 1963, p. 587-607. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:5864033]
Paneque A, Del Campo FF, Ramirez JM, Losada M.
Flavin nucleotide nitrate reductase from spinach.
Biochim. Biophys. Acta. 109 (1965) 79-85.
Spinacia oleracea |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:11289301]
Campbell WH.
Structure and function of eukaryotic NAD(P)H:nitrate reductase.
Cell. Mol. Life. Sci. 58 (2001) 194-204.
Pichia pastoris |
|---|
Reference
Authors
Title
Journal
|
4 [PMID:8534676]
Berks BC, Ferguson SJ, Moir JW, Richardson DJ.
Enzymes and associated electron transport systems that catalyse the
respiratory reduction of nitrogen oxides and oxyanions.
Biochim. Biophys. Acta. 1232 (1995) 97-173. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.7.1.2
IUBMB Enzyme Nomenclature: 1.7.1.2
ExPASy - ENZYME nomenclature database: 1.7.1.2
BRENDA, the Enzyme Database: 1.7.1.2
CAS: 9029-27-0 |
|---|
