| Entry |
|
| Name |
hydroxylamine oxidase;
HAO (ambiguous;
cf. EC 1.7.99.8, hydroxylamine oxidoreductase);
hydroxylamine oxidoreductase (ambiguous;
cf. EC 1.7.99.8, hydroxylamine oxidoreductase) |
| Class |
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With oxygen as acceptor
 |
| Sysname |
hydroxylamine:oxygen oxidoreductase |
| Reaction(IUBMB) |
hydroxylamine + O2 = nitrite + H2O [RN:R00793] |
| Reaction(KEGG) |
R00793
 |
| Substrate |
hydroxylamine [CPD:C00192];
O2 [CPD:C00007] |
| Product |
nitrite [CPD:C00088];
H2O [CPD:C00001] |
| Cofactor |
Heme [CPD:C00032] |
| Comment |
A hemoprotein with seven c-type hemes and one P-460-type heme per
subunit. |
| Pathway |
PATH: ec00910 Nitrogen metabolism |
| Orthology |
KO: K10535 hydroxylamine oxidase |
| Genes |
MCA: MCA0956
NOC: Noc_0892
NEU: NE0962(hao2)
NET: Neut_1672 Neut_1793
NMU: Nmul_A0805 Nmul_A1082 Nmul_A2662
CFF: CFF8240_0800
CCV: CCV52592_0434
GUR: Gura_1628
DDE: Dde_0300
DOL: Dole_1634
SFU: Sfum_2550
SIL: SPOA0201
MBU: Mbur_0467
 |
| Structures |
PDB: 1FGJ |
Reference Authors Title
Journal Organism
|
1 [PMID:7117545]
Hooper AB, Balny C.
Reaction of oxygen with hydroxylamine oxidoreductase of
Nitrosomonas: fast kinetics.
FEBS. Lett. 144 (1982) 299-303.
Nitrosomonas sp. |
Reference Authors Title
Journal Organism
|
2 [PMID:6289867]
Lipscomb JD, Hooper AB.
Resolution of multiple heme centers of hydroxylamine oxidoreductase
from Nitrosomonas. 1. Electron paramagnetic resonance spectroscopy.
Biochemistry. 21 (1982) 3965-72.
Nitrosomonas europeae [GN:neu] |
Reference Authors Title
Journal Organism
|
3 [PMID:5758552]
Rees MK.
Studies of the hydroxylamine metabolism of Nitrosomonas europaea. I.
Purification of hydroxylamine oxidase.
Biochemistry. 7 (1968) 353-66.
Nitrosomonas europeae [GN:neu] |
| Other DBs |
ExplorEnz - The Enzyme Database: 1.7.3.4
IUBMB Enzyme Nomenclature: 1.7.3.4
ExPASy - ENZYME nomenclature database: 1.7.3.4
BRENDA, the Enzyme Database: 1.7.3.4
CAS: 9075-43-8 |