KEGG   ENZYME: 1.8.4.1Help
Entry
EC 1.8.4.1                  Enzyme                                 

Name
glutathione---homocystine transhydrogenase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor
BRITE hierarchy
Sysname
glutathione:homocystine oxidoreductase
Reaction(IUBMB)
2 glutathione + homocystine = glutathione disulfide + 2 homocysteine [RN:R01110]
Reaction(KEGG)
Substrate
glutathione [CPD:C00051];
homocystine [CPD:C01817]
Product
glutathione disulfide [CPD:C00127];
homocysteine [CPD:C00155]
Comment
The reactions catalysed by this enzyme and by others in this subclass may be similar to those catalysed by EC 2.5.1.18 glutathione transferase.
History
EC 1.8.4.1 created 1961
Pathway
Cysteine and methionine metabolism
Glutathione metabolism
Reference
1  [PMID:13271447]
  Authors
RACKER E.
  Title
Glutathione-homocystine transhydrogenase.
  Journal
J. Biol. Chem. 217 (1955) 867-74.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-40-7

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