| Entry |
|
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| Name |
sterigmatocystin 8-O-methyltransferase;
sterigmatocystin methyltransferase;
O-methyltransferase II;
sterigmatocystin 7-O-methyltransferase (incorrect);
S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase (incorrect)
|
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
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| Sysname |
S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase
|
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + sterigmatocystin = S-adenosyl-L-homocysteine + 8-O-methylsterigmatocystin [RN: R03111]
|
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| Reaction(KEGG) |
|
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
sterigmatocystin [CPD: C00961]
|
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
8-O-methylsterigmatocystin [CPD: C03686]
|
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| Comment |
Dihydrosterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi.
|
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| Reference |
|
|---|
| Authors |
Bhatnagar D, McCormick SP, Lee LS, Hill RA. |
|---|
| Title |
Identification of O-methylsterigmatocystin as an aflatoxin B1 and G1 precursor in Aspergillus parasiticus. |
|---|
| Journal |
Appl. Environ. Microbiol. 53 (1987) 1028-33. |
|---|
| Organism |
Aspergillus parasiticus |
|---|
| Reference |
|
|---|
| Authors |
Yabe K, Ando Y, Hashimoto J, Hamasaki T. |
|---|
| Title |
Two distinct O-methyltransferases in aflatoxin biosynthesis. |
|---|
| Journal |
Appl. Environ. Microbiol. 55 (1989) 2172-7. |
|---|
| Organism |
Aspergillus parasiticus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 116958-29-3 |
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