| Entry |
|
|---|
| Name |
12-hydroxydihydrochelirubine 12-O-methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:12-hydroxydihydrochelirubine
12-O-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine =
S-adenosyl-L-homocysteine + dihydromacarpine [RN:R04705] |
|---|
| Reaction(KEGG) |
R04705
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
12-hydroxydihydrochelirubine [CPD:C05193] |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
dihydromacarpine [CPD:C05316] |
|---|
| Comment |
This reaction is part of the pathway for synthesis of
benzophenanthridine alkaloid macarpine in plants. |
|---|
| Pathway |
PATH: ec00950 Isoquinoline alkaloid biosynthesis
PATH: ec01063 Biosynthesis of alkaloids derived from shikimate
pathway
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
|
1
Kammerer, L., De-Eknamkul, W. and Zenk, M.H.
Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine
in dihydromacarpine formation by Thalictrum bulgaricum.
Phytochemistry 36 (1994) 1409-1416. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.120
IUBMB Enzyme Nomenclature: 2.1.1.120
ExPASy - ENZYME nomenclature database: 2.1.1.120
BRENDA, the Enzyme Database: 2.1.1.120
CAS: 158736-40-4 |
|---|
