| Entry |
|
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| Name |
precorrin-2 C20-methyltransferase |
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
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| Sysname |
S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase |
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine +
precorrin-3A [RN:R03948] |
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| Reaction(KEGG) |
R03948
 |
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| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
precorrin 2 [CPD:C02463] |
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| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
precorrin 3A [CPD:C05772] |
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| Pathway |
PATH: ec00860 Porphyrin and chlorophyll metabolism
PATH: ec01100 Metabolic pathways |
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| Orthology |
KO: K00593 precorrin-2 C20-methyltransferase |
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| Genes |
VSP: VS_2664
PAE: PA2904(cobI)
PAU: PA14_26510(cobI)
PAP: PSPA7_2250(cobI)
PAG: PLES_21601(cobI)
PPU: PP_4827(cobI)
PPF: Pput_4705
PPG: PputGB1_4883
PPW: PputW619_4617
PST: PSPTO_4875(cobI)
PSB: Psyr_4415
PSP: PSPPH_4458(cobI)
PFL: PFL_0659(cobI)
PFO: Pfl01_0606
PFS: PFLU0606(cobI)
PEN: PSEEN4869(cobI)
PMY: Pmen_4573
SSE: Ssed_2083
MCA: MCA2295
HHA: Hhal_1347
HCH: HCH_06475(cobI)
MMW: Mmwyl1_3374
CVI: CV_1565(cbiL)
RSO: RSp0621(cbiL)
BMA: BMA1163(cobI)
BMV: BMASAVP1_A1604(cobI)
BML: BMA10229_A0266(cobI)
BMN: BMA10247_0894(cobI)
BPS: BPSL1761(cobI)
BPM: BURPS1710b_2111(cobI)
BPL: BURPS1106A_1965(cobI)
BPD: BURPS668_1948(cobI)
BPR: GBP346_A1989(cobI)
BTE: BTH_I2400(cobI)
BVI: Bcep1808_1608
BUR: Bcep18194_A4822
BCN: Bcen_1192
BCH: Bcen2424_1672
BCM: Bcenmc03_1645
BCJ: BCAL1724(cobI)
BAM: Bamb_1572
BAC: BamMC406_1590
BMU: Bmul_1570
BMJ: BMULJ_01674(cobI)
BXE: Bxe_B1243
BPH: Bphy_3145
BPY: Bphyt_5371
BGL: bglu_1g18450
POL: Bpro_2774
PNA: Pnap_2158
AAV: Aave_0073
DAC: Daci_5849
VAP: Vapar_1019
CTT: CtCNB1_1876
MPT: Mpe_B0443(cobF)
AZO: azo3534(cbiL)
DAR: Daro_1688
APP: CAP2UW1_2614
GSU: GSU2995(cobI)
GME: Gmet_0482
GUR: Gura_0036
GLO: Glov_3652
GBM: Gbem_3542
GEO: Geob_0033
GEM: GM21_3608
PCA: Pcar_0476(cobI)
PPD: Ppro_3502
DVU: DVU0646(cobI)
DVL: Dvul_2314
DVM: DvMF_1500
DDE: Dde_3107
DDS: Ddes_0799
DMA: DMR_15490(cbiL)
DSA: Desal_2303
DBA: Dbac_1714
DPS: DP0211
DAL: Dalk_0446
DAT: HRM2_02310(cbiL)
SCL: sce0236(cobI)
SFU: Sfum_2135
MLO: mlr1380
SME: SMc03191(cobI)
SMD: Smed_2816
ATU: Atu2801(cobI)
ATC: AGR_C_5080
ARA: Arad_9594(cobI)
AVI: Avi_2637(cobI)
RET: RHE_PE00453(cobI)
REC: RHECIAT_PA0000376(cobI)
RLE: pRL110629(cobI)
RLT: Rleg2_6021
RLG: Rleg_7176
RHI: NGR_c29790(cobI)
BME: BMEI0713
BMF: BAB1_1306(cobI)
BMB: BruAb1_1289(cobI)
BMC: BAbS19_I12190
BMS: BR1288(cobI)
BMT: BSUIS_A1338(cobI)
BOV: BOV_1251(cobI)
BCS: BCAN_A1311(cobI)
BMR: BMI_I1301(cobI)
OAN: Oant_1897
BJA: blr3266(cobI)
BRA: BRADO4904(cobI)
BBT: BBta_3147(cobI)
RPA: RPA2089(cobI)
RPB: RPB_3179
RPC: RPC_1887
RPD: RPD_2319
RPE: RPE_2224
RPT: Rpal_2379
XAU: Xaut_3283
AZC: AZC_3938
MEX: Mext_1436
MEA: Mex_1p1325(cobI)
MDI: METDI2097(cobI)
MRD: Mrad2831_3118
MET: M446_2441
MPO: Mpop_1433
MCH: Mchl_1711 Mchl_5690
MNO: Mnod_2152
BID: Bind_3510
MSL: Msil_3265
SIL: SPO2866(cobI)
SIT: TM1040_2213
RSP: RSP_2826(cobI)
RSH: Rsph17029_1470
RSQ: Rsph17025_1520
RSK: RSKD131_1137
JAN: Jann_2928
RDE: RD1_3824(cobI)
PDE: Pden_2535
DSH: Dshi_0174(cobI)
NAR: Saro_0339
GBE: GbCGDNIH1_0661
APT: APA01_14540
RRU: Rru_A2990
MAG: amb0297
MGM: Mmc1_3131
GKA: GK1799
GTN: GTNG_1688(cbiL)
GWC: GWCH70_1556
GYC: GYMC61_2610
AFL: Aflv_2174
LSP: Bsph_3439
BBE: BBR47_12510(cbiL)
CPY: Cphy_1375
CCE: Ccel_1271
DSY: DSY4070(cobI)
DHD: Dhaf_1297
DRM: Dred_2735
DAE: Dtox_0554 Dtox_1293
PTH: PTH_0953(cobF)
DAU: Daud_1854
HMO: HM1_2388(cbiL)
ERE: EUBREC_1133
TPD: Teth39_1892
MTA: Moth_1091
ADG: Adeg_0933
NTH: Nther_0932
MTU: Rv2066(cobI)
MTC: MT2126(cobIJ)
MRA: MRA_2080(cobI)
MTF: TBFG_12102
MBO: Mb2092(cobI)
MBB: BCG_2085(cobI)
MPA: MAP1812(cobI)
MAV: MAV_2430
MSM: MSMEG_3873
MUL: MUL_2290(cobI)
MVA: Mvan_3431
MGI: Mflv_3104
MAB: MAB_2198c
MMC: Mmcs_2487
MKM: Mkms_2532
MJL: Mjls_2524
MMI: MMAR_3046(cobI)
CDI: DIP1233(cobIJ)
NFA: nfa31520(cobIJ)
RHA: RHA1_ro00174
SCO: SCO1853(cobI)
SMA: SAV_6411(cobI)
SGR: SGR_3822
PAC: PPA0420
NCA: Noca_2891 Noca_2892
TFU: Tfu_0316
TCU: Tcur_1313
FRA: Francci3_1521
FRE: Franean1_4161
FAL: FRAAL2333(cobI)
SEN: SACE_5951
STP: Strop_2524
SAQ: Sare_2706
CAI: Caci_6036
RXY: Rxyl_0639
AFO: Afer_0535
SHI: Shel_24850
LIL: LB159(cobI)
LIC: LIC20129(cobI)
LBJ: LBJ_4183(cobF)
LBL: LBL_4198(cobF)
BVU: BVU_3076
PGN: PGN_1490
PDI: BDI_1016
CPI: Cpin_4474
STR: Sterm_1012
TAI: Taci_0048
SYW: SYNW0653(cobI)
SYC: syc2241_c(cobI)
SYF: Synpcc7942_1853
SYD: Syncc9605_2022
SYE: Syncc9902_0650
SYG: sync_0590(cobI)
SYR: SynRCC307_0460(cobI)
SYX: SynWH7803_0561(cobI)
CYA: CYA_0903(cobI)
CYB: CYB_2189(cobI)
TEL: tlr1449(cobI)
MAR: MAE_02740(cobI)
CYT: cce_0538(cbiL)
CYP: PCC8801_3100
CYC: PCC7424_4665
CYN: Cyan7425_1032
CYH: Cyan8802_3020
GVI: gvip028(cobI)
ANA: all0455
NPU: Npun_F6483
AVA: Ava_2865
PMA: Pro0386(cobF)
PMM: PMM0389(cobI)
PMT: PMT0198(cobI)
PMN: PMN2A_1723
PMI: PMT9312_0385
PMB: A9601_04401(cobI)
PMC: P9515_04511(cobI)
PMF: P9303_21591(cobI)
PMG: P9301_04091(cobI)
PMH: P9215_04661(cobI)
PMJ: P9211_03851(cobI)
PME: NATL1_04401(cobI)
TER: Tery_0768
AMR: AM1_1842(cobF)
CPC: Cpar_1478
CLI: Clim_1011
PAA: Paes_1291
CTS: Ctha_2221
RRS: RoseRS_0570
RCA: Rcas_0639
CAU: Caur_2567
CAG: Cagg_1266
CHL: Chy400_2774
DGE: Dgeo_2358
DDR: Deide_2p01600
TME: Tmel_0701
NMR: Nmar_0058
 |
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| Structures |
PDB: 2E0K 2E0N |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:1451790]
Roessner CA, Warren MJ, Santander PJ, Atshaves BP, Ozaki S,
Stolowich NJ, Iida K, Scott AI.
Expression of 9 Salmonella typhimurium enzymes for cobinamide
synthesis. Identification of the 11-methyl and 20-methyl
transferases of corrin biosynthesis.
FEBS. Lett. 301 (1992) 73-8.
Salmonella typhimurium |
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Reference
Authors
Title
Journal
Organism
|
2 [PMID:7606163]
Roessner CA, Spencer JB, Ozaki S, Min C, Atshaves BP, Nayar P,
Anousis N, Stolowich NJ, Holderman MT, Scott AI.
Overexpression in Escherichia coli of 12 vitamin B12 biosynthetic
enzymes.
Protein. Expr. Purif. 6 (1995) 155-63.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:8226690]
Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F.
Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas
denitrificans.
J. Bacteriol. 175 (1993) 7430-40.
Pseudomonas denitrificans |
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| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.130
IUBMB Enzyme Nomenclature: 2.1.1.130
ExPASy - ENZYME nomenclature database: 2.1.1.130
BRENDA, the Enzyme Database: 2.1.1.130
CAS: 131554-12-6 |
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