KEGG   ENZYME: 2.1.1.147Help
Entry
EC 2.1.1.147                Enzyme                                 
Name
corydaline synthase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + palmatine + 2 NADPH + H+ = S-adenosyl-L-homocysteine + corydaline + 2 NADP+ [RN:R07241]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
palmatine [CPD:C05315];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
corydaline [CPD:C15530];
NADP+ [CPD:C00006]
Comment
Also acts on 7,8-dihydropalmatine.
Pathway
Isoquinoline alkaloid biosynthesis
Reference
1
  Authors
Rueffer, M., Bauer, W. and Zenk, M.H.
  Title
The formation of corydaline and related alkaloids in Corydalis cava in vivo and in vitro.
  Journal
Canad. J. Chem. 72 (1994) 170-175.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
155807-67-3
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