KEGG   ENZYME: 2.1.1.17Help
Entry
EC 2.1.1.17                 Enzyme                                 
Name phosphatidylethanolamine N-methyltransferase;
PEMT;
LMTase;
lipid methyl transferase;
phosphatidylethanolamine methyltransferase;
phosphatidylethanolamine-N-methylase;
phosphatidylethanolamine-S-adenosylmethionine methyltransferase
Class Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase
Reaction(IUBMB) S-adenosyl-L-methionine + phosphatidylethanolamine =
S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
[RN:R02056]
Reaction(KEGG) R02056
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Substrate S-adenosyl-L-methionine [CPD:C00019];
phosphatidylethanolamine [CPD:C00350]
Product S-adenosyl-L-homocysteine [CPD:C00021];
phosphatidyl-N-methylethanolamine [CPD:C01241]
Pathway PATH: ec00564  Glycerophospholipid metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00551  phosphatidylethanolamine N-methyltransferase
Genes HSA: 10400(PEMT)
PTR: 454478(PEMT)
MCC: 699083(PEMT)
MMU: 18618(Pemt)
RNO: 25511(Pemt)
CFA: 479526(PEMT)
BTA: 360197(PEMT)
SSC: 397654(PEMT)
ECB: 100050945
MDO: 100010012
OAA: 100079865
GGA: 416508(PEMT)
TGU: 100230786
XLA: 447155
XTR: 448594(pemt)
DRE: 393127
SPU: 581512
SCE: YGR157W(CHO2)
AGO: AGOS_AFR110C
PIC: PICST_57055(CHO2)
CGR: CAGL0E03201g
YLI: YALI0E06061g
SPO: SPBC26H8.03(cho2)
NCR: NCU08045
MGR: MGG_07110
ANI: AN2154.2
AFM: AFUA_2G15970
AOR: AO090012000204
DDI: DDBDRAFT_0168929
LMA: LmjF31.2290 LmjF31.3120
MAQ: Maqu_1462
LPN: lpg2158(pmtA)
LPF: lpl2086
LPP: lpp2097
LPC: LPC_1619
MCA: MCA3065
NOC: Noc_0914
AEH: Mlg_0492
HHA: Hhal_0826
CSA: Csal_2810
AFE: Lferr_2360
AFR: AFE_2739
CVI: CV_4378
NMU: Nmul_A0349
EBA: ebA6680(pemT)
DAR: Daro_3485
APP: CAP2UW1_1175
PLA: Plav_2189
RET: RHE_CH00316(ypch00118) RHE_CH01201(ypch00401)
REC: RHECIAT_CH0001293
RLE: RL0333(pmtA) RL1338(pmtA)
RLT: Rleg2_0843
BME: BMEI2000
BMF: BAB1_2131
BMS: BR2127(pmtA)
BOV: BOV_2043(pmtA)
BJA: bll6634(pmtA) bll6994
BRA: BRADO5696 BRADO5893
BBT: BBta_1882 BBta_6211
RPA: RPA1307 RPA3970
RPB: RPB_1620 RPB_4115
RPC: RPC_0988 RPC_1444
RPD: RPD_1629 RPD_3961
RPE: RPE_0347 RPE_1038 RPE_1464
NWI: Nwi_0604 Nwi_0696
NHA: Nham_0696
XAU: Xaut_0403
AZC: AZC_4349
MEX: Mext_4097
MRD: Mrad2831_5064
MET: M446_5117
MPO: Mpop_4578
MCH: Mchl_4465
MNO: Mnod_6066
SIL: SPOA0294(pmtA)
SIT: TM1040_3086
RSP: RSP_0721(pmtA)
RSH: Rsph17029_2376
RSQ: Rsph17025_2440
PDE: Pden_4690
DSH: Dshi_2712
ZMO: ZMO0776
GOX: GOX1862
GBE: GbCGDNIH1_0800 GbCGDNIH1_2260
ACR: Acry_2168
GDI: GDI_2102(pmtA)
GDJ: Gdia_0321
MTA: Moth_0018
AYW: AYWB_415
NCA: Noca_2195 Noca_3328
TFU: Tfu_0735
SEN: SACE_4353
SRU: SRU_2332
RBA: RB2970
AVA: Ava_2605
TTH: TTC1366
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:25437]
Hirata F, Viveros OH, Diliberto EJ Jr, Axelrod J.
Identification and properties of two methyltransferases in
conversion of phosphatidylethanolamine to phosphatidylcholine.
Proc. Natl. Acad. Sci. U. S. A. 75 (1978) 1718-21.
Bos taurus [GN:bta]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:5773456]
Morgan TE.
Isolation and characterization of lipid N-methylrtansferase from dog
lung.
Biochim. Biophys. Acta. 178 (1969) 21-34.
Canis familiaris [GN:cfa]
Reference
  Authors
  Title


  Journal
  Organism
 3  [PMID:438165]
Schneider WJ, Vance DE.
Conversion of phosphatidylethanolamine to phosphatidylcholine in rat
liver. Partial purification and characterization of the enzymatic
activities.
J. Biol. Chem. 254 (1979) 3886-91.
Rattus norvegicus [GN:rno]
Other DBs ExplorEnz - The Enzyme Database: 2.1.1.17
IUBMB Enzyme Nomenclature: 2.1.1.17
ExPASy - ENZYME nomenclature database: 2.1.1.17
BRENDA, the Enzyme Database: 2.1.1.17
CAS: 37256-91-0
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