| Entry |
|
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| Name |
guanidinoacetate N-methyltransferase;
GA methylpherase;
guanidinoacetate methyltransferase;
guanidinoacetate transmethylase;
methionine-guanidinoacetic transmethylase;
guanidoacetate methyltransferase
|
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
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| Sysname |
S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase
|
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine [RN: R01883]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
guanidinoacetate [CPD: C00581]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
creatine [CPD: C00300]
|
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| Pathway |
| Glycine, serine and threonine metabolism | | Arginine and proline metabolism | | Metabolic pathways |
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| Orthology |
| guanidinoacetate N-methyltransferase |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | NVE: | | AQU: | | DHA: | | PIC: | | CAL: | | FAL: | |
» show all
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| Reference |
1 |
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| Authors |
Cantoni, G.L. and Scarano, E. |
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| Title |
The formation of S-adenosylhomocysteine in enzymatic transmethylation reactions. |
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| Journal |
J. Am. Chem. Soc. 76 (1954) 4744. |
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| Reference |
|
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| Authors |
CANTONI GL, VIGNOS PJ Jr. |
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| Title |
Enzymatic mechanism of creatine synthesis. |
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| Journal |
J. Biol. Chem. 209 (1954) 647-59. |
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| Organism |
Bos taurus [GN: bta], Sus scofa [GN: ssc], Cavia porcellus, Oryctolagus cuniculus |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9029-75-8 |
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