| Entry |
|
| Name |
indolepyruvate C-methyltransferase;
indolepyruvate methyltransferase;
indolepyruvate 3-methyltransferase;
indolepyruvic acid methyltransferase;
S-adenosyl-L-methionine:indolepyruvate C-methyltransferase |
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
| Sysname |
S-adenosyl-L-methionine: (indol-3-yl)pyruvate C-methyltransferase |
| Reaction(IUBMB) |
S-adenosyl-L-methionine + (indol-3-yl)pyruvate =
S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate
[RN:R01972] |
| Reaction(KEGG) |
R01972;
(other) R01973
 |
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
(indol-3-yl)pyruvate [CPD:C00331] |
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
(S)-3-(indol-3-yl)-2-oxobutanoate |
| Pathway |
PATH: ec00380 Tryptophan metabolism |
Reference Authors Title
Journal Organism
|
1 [PMID:5490210]
Hornemann U, Speedie MK, Hurley LH, Floss HG.
Demonstration of a C-methylating enzyme in cell free extracts of
indolmycin-producing Streptomyces griseus.
Biochem. Biophys. Res. Commun. 39 (1970) 594-9.
Streptomyces griseus [GN:sgr] |
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.47
IUBMB Enzyme Nomenclature: 2.1.1.47
ExPASy - ENZYME nomenclature database: 2.1.1.47
BRENDA, the Enzyme Database: 2.1.1.47
CAS: 54576-88-4 |