| Entry |
|
|---|
| Name |
[cytochrome c]-lysine N-methyltransferase;
cytochrome c (lysine) methyltransferase;
cytochrome c methyltransferase;
cytochrome c-specific protein methylase III;
cytochrome c-specific protein-lysine methyltransferase;
S-adenosyl-L-methionine:[cytochrome c]-L-lysine
6-N-methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:[cytochrome c]-L-lysine N6-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + [cytochrome c]-L-lysine =
S-adenosyl-L-homocysteine + [cytochrome c]-N6-methyl-L-lysine
[RN:R04145] |
|---|
| Reaction(KEGG) |
R04145;
(other) R03875 R04866 R04867
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
[cytochrome c]-L-lysine |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
[cytochrome c]-N6-methyl-L-lysine |
|---|
| Comment |
One of a group of enzymes methylating proteins; see also EC 2.1.1.43
histone-lysine N-methyltransferase and EC 2.1.1.60 calmodulin-lysine
N-methyltransferase. |
|---|
| Pathway |
PATH: ec00310 Lysine degradation |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:203592]
Durban E, Nochumson S, Kim S, Paik WK, Chan SK.
Cytochrome c-specific protein-lysine methyltransferase from
Neurospora crassa. Purification, characterization, and substrate
requirements.
J. Biol. Chem. 253 (1978) 1427-35.
Neurospora crassa [GN:ncr] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:196592]
Nochumson S, Durban E, Kim S, Paik WK.
Cytochrome c-specific protein methylase III from Neurospora crassa.
Biochem. J. 165 (1977) 11-8.
Neurospora crassa [GN:ncr] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:6282265]
Valentine J, Pettigrew GW.
A cytochrome c methyltransferase from Crithidia oncopelti.
Biochem. J. 201 (1982) 329-38.
Crithidia oncopelti |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.59
IUBMB Enzyme Nomenclature: 2.1.1.59
ExPASy - ENZYME nomenclature database: 2.1.1.59
BRENDA, the Enzyme Database: 2.1.1.59
CAS: 82047-78-7 |
|---|
