| Entry |
|
|---|
| Name |
calmodulin-lysine N-methyltransferase;
S-adenosylmethionine:calmodulin (lysine) N-methyltransferase;
S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + calmodulin L-lysine =
S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine
[RN:R04062] |
|---|
| Reaction(KEGG) |
R04062;
(other) R03875 R04866 R04867
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
calmodulin L-lysine [CPD:C02816] |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
calmodulin N6-methyl-L-lysine [CPD:C03941] |
|---|
| Comment |
One of a group of enzymes methylating proteins; see also EC 2.1.1.43
histone-lysine N-methyltransferase and EC 2.1.1.59
[cytochrome-c]-lysine N-methyltransferase. |
|---|
| Pathway |
PATH: ec00310 Lysine degradation |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6773954]
Sitaramayya A, Wright LS, Siegel FL.
Enzymatic methylation of calmodulin in rat brain cytosol.
J. Biol. Chem. 255 (1980) 8894-900.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.60
IUBMB Enzyme Nomenclature: 2.1.1.60
ExPASy - ENZYME nomenclature database: 2.1.1.60
BRENDA, the Enzyme Database: 2.1.1.60
CAS: 75603-20-2 |
|---|
