| Entry |
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| Name |
caffeate O-methyltransferase;
caffeate methyltransferase;
caffeate 3-O-methyltransferase;
S-adenosyl-L-methionine:caffeic acid-O-methyltransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
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| Sysname |
S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate [RN: R03366]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
3,4-dihydroxy-trans-cinnamate [CPD: C01197]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
3-methoxy-4-hydroxy-trans-cinnamate [CPD: C01494]
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| Comment |
3,4-Dihydroxybenzaldehyde and catechol can act as acceptors, but more slowly.
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| History |
EC 2.1.1.68 created 1984
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| Pathway |
| Phenylpropanoid biosynthesis | | Metabolic pathways | | Biosynthesis of secondary metabolites |
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| Orthology |
| caffeic acid 3-O-methyltransferase |
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| Genes |
 |
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| Reference |
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| Authors |
Ebel J, Schaller-Hekeler B, Knobloch KH, Wellman E, Grisebach H, Hahlbrock K. |
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| Title |
Coordinated changes in enzyme activities of phenylpropanoid metabolism during the growth of soybean cell suspension cultures. |
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| Journal |
Biochim. Biophys. Acta. 362 (1974) 417-24. |
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| Organism |
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| Reference |
|
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| Authors |
Poulton JE, Butt VS. |
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| Title |
Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L). |
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| Journal |
Biochim. Biophys. Acta. 403 (1975) 301-14. |
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| Organism |
Beta vulgaris |
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| Reference |
3 |
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| Authors |
Shimada, M., Kuroda, H. and Higuchi, T. |
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| Title |
Evidence for the formation of methoxyl groups of ferulic and sinapic acid in Bambusa by the same O-methyltransferase. |
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| Journal |
Phytochemistry 12 (1973) 2873-2875. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 50936-45-3 |
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