KEGG ENZYME: 2.1.1.68

ENZYME: 2.1.1.68

Entry

EC 2.1.1.68 Enzyme

Name

caffeate O-methyltransferase;
caffeate methyltransferase;
caffeate 3-O-methyltransferase;
S-adenosyl-L-methionine:caffeic acid-O-methyltransferase

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate [RN:R03366]

Reaction(KEGG)

R03366;
(other) R02379 R06574 R06575 R06576 R06577

Substrate

S-adenosyl-L-methionine [CPD:C00019];
3,4-dihydroxy-trans-cinnamate [CPD:C01197]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
3-methoxy-4-hydroxy-trans-cinnamate [CPD:C01494]

Comment

3,4-Dihydroxybenzaldehyde and catechol can act as acceptors, but more slowly.

History

EC 2.1.1.68 created 1984

Pathway

ec00940	Phenylpropanoid biosynthesis
ec01100	Metabolic pathways
ec01110	Biosynthesis of secondary metabolites

Orthology

K13066

caffeic acid 3-O-methyltransferase

Genes

ATH:	AT5G54160(OMT1)
ALY:	ARALYDRAFT_313855 ARALYDRAFT_314426 ARALYDRAFT_353659 ARALYDRAFT_354029 ARALYDRAFT_472349 ARALYDRAFT_472352 ARALYDRAFT_475033 ARALYDRAFT_476917 ARALYDRAFT_476918 ARALYDRAFT_495497(ATOMT1) ARALYDRAFT_675184 ARALYDRAFT_684972 ARALYDRAFT_893153 ARALYDRAFT_913747 ARALYDRAFT_913762 ARALYDRAFT_918528(ATOMT1)
CRB:	CARUB_v10009584mg CARUB_v10011795mg CARUB_v10015208mg CARUB_v10017422mg CARUB_v10020455mg CARUB_v10020496mg CARUB_v10020520mg CARUB_v10021394mg CARUB_v10021455mg CARUB_v10022155mg CARUB_v10022215mg CARUB_v10026645mg CARUB_v10027790mg
EUS:	EUTSA_v10002019mg EUTSA_v10007945mg EUTSA_v10007957mg EUTSA_v10007964mg EUTSA_v10008040mg EUTSA_v10013896mg EUTSA_v10013897mg EUTSA_v10013908mg EUTSA_v10014001mg EUTSA_v10015575mg EUTSA_v10018703mg EUTSA_v10018739mg EUTSA_v10023537mg EUTSA_v10025490mg EUTSA_v10025520mg EUTSA_v10025522mg EUTSA_v10027501mg
BRP:	103827916 103829388 103829389 103829390 103830562 103830566 103830598 103832136 103832198 103833645 103833646 103834597 103835758 103835759 103838067 103844876 103844878 103851608 103851985 103853080 103853081 103857055 103861716 103868698 103870469 103872905
CIT:	102609398 102609664 102609976 102610562 102611981 102612475 102612776 102613152 102617285 102618148 102619425 102620276 102620338 102620533 102621307 102622352 102623037 102623705 102624192 102625166 102625353 102626016 102626202 102627175 102627553 102629454 102629858 102630049 102630331 102630642
CIC:	CICLE_v10001555mg CICLE_v10001661mg CICLE_v10003181mg CICLE_v10003323mg CICLE_v10003428mg CICLE_v10003445mg CICLE_v10003534mg CICLE_v10003737mg CICLE_v10005230mg CICLE_v10005251mg CICLE_v100108602m CICLE_v10012042mg CICLE_v10013542mg CICLE_v10015685mg CICLE_v10017649mg CICLE_v10017683mg CICLE_v10018226mg CICLE_v10018306mg CICLE_v10020377mg CICLE_v10020761mg CICLE_v100208141m CICLE_v100208142m CICLE_v10020820mg CICLE_v10020821mg CICLE_v10020828mg CICLE_v10020870mg CICLE_v10020873mg CICLE_v10020874mg CICLE_v10020875mg CICLE_v10020880mg CICLE_v10021670mg CICLE_v10021888mg CICLE_v10023459mg CICLE_v10023568mg CICLE_v10023965mg CICLE_v10023994mg CICLE_v10024037mg CICLE_v10024098mg CICLE_v10024389mg CICLE_v10026359mg CICLE_v10026361mg CICLE_v10031949mg CICLE_v10031951mg CICLE_v10031952mg CICLE_v10031953mg
TCC:	TCM_005024 TCM_015522 TCM_015596 TCM_018684 TCM_025869 TCM_025871 TCM_025877 TCM_035137 TCM_040757 TCM_040759 TCM_040763 TCM_044687 TCM_045925
EGR:	104415145 104415146 104416154 104416155 104416156 104416157 104416158 104416159 104416162 104417513 104420045 104424243 104424567 104429247 104429248 104430810 104430849 104437195 104437201 104437219 104439341 104444139 104445297 104445600 104445601 104446176 104447135 104447137 104447142 104447255 104447523 104449485 104449526 104449527 104449528 104450510 104452413 104452416 104455705 104455715 104456234
GMX:	100777636 100779492 100780100 100784030 100787536 100788873 100789402 100793053 100798295 100798347 100798874 100802593 100803633
PVU:	PHAVU_003G006000g PHAVU_003G006100g PHAVU_003G006200g PHAVU_005G0323000 PHAVU_007G090100g PHAVU_007G091000g PHAVU_008G040200g PHAVU_009G044400g PHAVU_009G2586001 PHAVU_009G258700g PHAVU_009G258800g PHAVU_009G258900g PHAVU_009G259000g PHAVU_009G259100g PHAVU_009G259200g PHAVU_009G259300g PHAVU_009G259500g PHAVU_010G120200g PHAVU_L008600g
MTR:	MTR_1g050220 MTR_3g021430 MTR_3g021440 MTR_3g092900 MTR_5g098170 MTR_6g060290 MTR_6g078850 MTR_7g011900 MTR_7g011990 MTR_7g012020 MTR_7g012040 MTR_7g012070 MTR_7g012090 MTR_7g118300 MTR_7g118310 MTR_7g118320
CAM:	101489515 101489645 101492092 101499314 101499972 101500319 101502419 101512074 101512403 101513904 101514542 101514683
FVE:	101292538 101294295 101295664 101296734 101308514 101314167 101314449 101314735
PPER:	PRUPE_ppa007212mg PRUPE_ppa007229mg PRUPE_ppa007511mg PRUPE_ppa015120mg PRUPE_ppa015423mg PRUPE_ppa015896mg PRUPE_ppa018244mg PRUPE_ppa019149mg PRUPE_ppa019437mg PRUPE_ppa019499mg PRUPE_ppa021447mg PRUPE_ppa024343mg
PMUM:	103319810 103322531 103333559 103342357 103342358 103342359(OMT1) 103342360 103343871
MDM:	103405809 103406240 103406241 103406249 103406602 103410332 103410396 103411915 103416301 103416926 103419371 103420798 103420847 103421923 103422036 103426402 103426499 103426529 103426534 103428516 103428558 103429450 103429452 103431087 103431107 103433538 103435029 103439452 103439955 103439956 103439958 103443723 103444096 103444340 103445469 103445678
PXB:	103927980 103927981 103927983 103935025 103935026 103940328 103943351 103943352 103943506 103951323 103951351 103951352 103951568 103951571 103951572 103951578 103951641 103956347 103966079 103966114
CSV:	101204109 101205290 101210788 101214675 101214916 101230683
CMO:	103491014 103491140 103501180 103503246
RCU:	RCOM_0561350 RCOM_0561360 RCOM_0596300 RCOM_0686150 RCOM_1314480 RCOM_1340190 RCOM_1340220 RCOM_1453200
POP:	POPTR_0001s45530g(POPTRDRAFT_550470) POPTR_0002s07730g POPTR_0002s18120g POPTR_0002s18130g POPTR_0002s18150g(POPTRDRAFT_552360) POPTR_0002s18160g(POPTRDRAFT_799151) POPTR_0005s20630g POPTR_0011s15360g(POPTRDRAFT_806142) POPTR_0012s00670g(POPTRDRAFT_834247) POPTR_0014s10210g(POPTRDRAFT_774571) POPTR_0014s10220g(POPTRDRAFT_731466) POPTR_0015s00550g(POPTRDRAFT_824484) POPTR_0016s10450g POPTR_0019s11400g
VVI:	100232921(COMT) 100251265 100253843 100255690 100260649 100260763 100265214 100265976 100265990 100854172
SLY:	101247834 101251452 101258157 101261963 101262824
SOT:	102580081 102598963 102599285 102599938 102601059 102601955
BVG:	104887972 104888149 104888150 104888557 104893230 104897755 104901566 104901641 104901795 104901881 104901967 104902057 104902142 104902234 104907961 104908865
DOSA:	Os04t0104900-01(Os04g0104900) Os04t0175900-01(Os04g0175900) Os12t0199500-00(Os12g0199500) Os12t0240900-00(Os12g0240900)
OBR:	102717362 102719765
BDI:	100833782 100838174 100842290
SBI:	SORBI_01g015803(SORBIDRAFT_01g015803) SORBI_01g033245(SORBIDRAFT_01g033245) SORBI_01g042900(SORBIDRAFT_01g042900) SORBI_07g004680(SORBIDRAFT_07g004680) SORBI_07g004690(SORBIDRAFT_07g004690) SORBI_07g004710(SORBIDRAFT_07g004710)
ZMA:	100125646(comt) 101027166 103640406
SITA:	101754689 101761321 101765311 101772386 101783292
PDA:	103696092 103706414 103716997
MUS:	103971889 103971898 103971905 103971914 103971925 103971934 103971944 103971953 103971962 103972218 103972714 103973475 103973830 103973854 103973864 103973874 103973932 103974217 103974740 103974741 103974791 103974925 103975177 103978658 103980348 103982815 103998763 103998764 103998765 103999438 104000428
ATR:	s00001p00272250(AMTR_s00001p00272250)
SMO:	SELMODRAFT_112597 SELMODRAFT_124122 SELMODRAFT_124205 SELMODRAFT_133702 SELMODRAFT_133835 SELMODRAFT_134942 SELMODRAFT_134972 SELMODRAFT_227279 SELMODRAFT_227505 SELMODRAFT_3189 SELMODRAFT_3192 SELMODRAFT_76630 SELMODRAFT_78541 SELMODRAFT_83100 SELMODRAFT_85724 SELMODRAFT_85878 SELMODRAFT_94918 SELMODRAFT_95652 SELMODRAFT_96831 SELMODRAFT_97635
PPP:	PHYPADRAFT_135040 PHYPADRAFT_175146

» show all

Reference

1 [PMID:4472044]

Authors

Ebel J, Schaller-Hekeler B, Knobloch KH, Wellman E, Grisebach H, Hahlbrock K.

Title

Coordinated changes in enzyme activities of phenylpropanoid metabolism during the growth of soybean cell suspension cultures.

Journal

Biochim. Biophys. Acta. 362 (1974) 417-24.

Reference

2 [PMID:241400]

Authors

Poulton JE, Butt VS.

Title

Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L).

Journal

Biochim. Biophys. Acta. 403 (1975) 301-14.

Reference

Authors

Shimada, M., Kuroda, H. and Higuchi, T.

Title

Evidence for the formation of methoxyl groups of ferulic and sinapic acid in Bambusa by the same O-methyltransferase.

Journal

Phytochemistry 12 (1973) 2873-2875.

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.68

IUBMB Enzyme Nomenclature:

2.1.1.68

ExPASy - ENZYME nomenclature database:

2.1.1.68

BRENDA, the Enzyme Database:

2.1.1.68

CAS:

50936-45-3

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (39)   
   KEGG PATHWAY (6)   
   KEGG MODULE (33)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (21)   
   KEGG REACTION (6)   
   KEGG RPAIR (13)   
   KEGG RCLASS (2)   
Gene (621)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (495)   
   KEGG DGENES (125)   
Protein sequence (103)   
   UniProt (50)   
   SWISS-PROT (21)   
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   PDBSTR (12)   
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DNA sequence (82)   
   RefSeq(nuc) (31)   
   GenBank (31)   
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