KEGG   ENZYME: 2.1.1.88Help
Entry
EC 2.1.1.88                 Enzyme                                 

Name
8-hydroxyquercetin 8-O-methyltransferase;
flavonol 8-O-methyltransferase;
flavonol 8-methyltransferase;
S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase;
8-hydroxyquercitin 8-O-methyltransferase [mis-spelt]
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:3,5,7,8,3',4'-hexahydroxyflavone 8-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 3,5,7,8,3',4'-hexahydroxyflavone = S-adenosyl-L-homocysteine + 3,5,7,3',4'-pentahydroxy-8-methoxyflavone [RN:R04398]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
3,5,7,8,3',4'-hexahydroxyflavone
Product
S-adenosyl-L-homocysteine [CPD:C00021];
3,5,7,3',4'-pentahydroxy-8-methoxyflavone
Comment
Also acts on 8-hydroxykaempferol, but not on the glycosides of 8-hydroxyflavonols. An enzyme from the flower buds of Lotus corniculatus.
History
EC 2.1.1.88 created 1989
Reference
1  [PMID:4076180]
  Authors
Jay M, De Luca V, Ibrahim RK.
  Title
Purification, properties and kinetic mechanism of flavonol 8-O-methyltransferase from Lotus corniculatus L.
  Journal
Eur. J. Biochem. 153 (1985) 321-5.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
99775-17-4

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