| Entry |
|
|---|
| Name |
D-alanine 2-hydroxymethyltransferase;
2-methylserine hydroxymethyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Hydroxymethyl-, formyl- and related transferases
 |
|---|
| Sysname |
5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase |
|---|
| Reaction(IUBMB) |
5,10-methylenetetrahydrofolate + D-alanine + H2O = tetrahydrofolate
+ 2-methylserine [RN:R01225] |
|---|
| Reaction(KEGG) |
R01225
 |
|---|
| Substrate |
5,10-methylenetetrahydrofolate [CPD:C00143];
D-alanine [CPD:C00133];
H2O [CPD:C00001] |
|---|
| Product |
tetrahydrofolate [CPD:C00101];
2-methylserine [CPD:C02115] |
|---|
| Comment |
Also acts on 2-hydroxymethylserine. |
|---|
| Pathway |
PATH: ec00670 One carbon pool by folate
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14001018]
WILSON EM, SNELL EE.
Metabolism of alpha-methylserine. I. alpha-Methylserine
hydroxymethyltransferase.
J. Biol. Chem. 237 (1962) 3171-9.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.2.7
IUBMB Enzyme Nomenclature: 2.1.2.7
ExPASy - ENZYME nomenclature database: 2.1.2.7
BRENDA, the Enzyme Database: 2.1.2.7
CAS: 9075-76-7 |
|---|
