| Entry |
|
|---|
| Name |
methylmalonyl-CoA carboxytransferase;
transcarboxylase;
methylmalonyl coenzyme A carboxyltransferase;
methylmalonyl-CoA transcarboxylase;
oxalacetic transcarboxylase;
methylmalonyl-CoA carboxyltransferase;
methylmalonyl-CoA carboxyltransferase;
(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase;
(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxytransferase
carboxytransferase [incorrect] |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Carboxy- and carbamoyltransferases
 |
|---|
| Sysname |
(S)-methylmalonyl-CoA:pyruvate carboxytransferase |
|---|
| Reaction(IUBMB) |
(S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate
[RN:R00930] |
|---|
| Reaction(KEGG) |
R00930;
(other) R00353
 |
|---|
| Substrate |
(S)-methylmalonyl-CoA [CPD:C00683];
pyruvate [CPD:C00022] |
|---|
| Product |
propanoyl-CoA [CPD:C00100];
oxaloacetate [CPD:C00036] |
|---|
| Cofactor |
Zinc [CPD:C00038];
Biotin [CPD:C00120];
Cobalt ion [CPD:C00175] |
|---|
| Comment |
A biotinyl-protein, containing cobalt and zinc. |
|---|
| Pathway |
PATH: ec00640 Propanoate metabolism |
|---|
| Orthology |
KO: K03416 methylmalonyl-CoA carboxyltransferase |
|---|
| Genes |
CAK: Caul_4464
MSM: MSMEG_6577
CGL: NCgl1273(cgl1327)
PAC: PPA2007
 |
|---|
| Structures |
PDB: 1DCZ 1DD2 1ON3 1ON9 1RQB 1RQE 1RQH 1RR2 1S3H 1U5J
2D5D 2EVB |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:2920730]
Hoffmann A, Hilpert W, Dimroth P.
The carboxyltransferase activity of the sodium-ion-translocating
methylmalonyl-CoA decarboxylase of Veillonella alcalescens.
Eur. J. Biochem. 179 (1989) 645-50.
Veillonella alcalescens |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:16590594]
Swick RW, Wood HG.
THE ROLE OF TRANSCARBOXYLATION IN PROPIONIC ACID FERMENTATION.
Proc. Natl. Acad. Sci. U. S. A. 46 (1960) 28-41.
Propionibacterium shermanii |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.3.1
IUBMB Enzyme Nomenclature: 2.1.3.1
ExPASy - ENZYME nomenclature database: 2.1.3.1
UM-BBD (Biocatalysis/Biodegradation Database): 2.1.3.1
BRENDA, the Enzyme Database: 2.1.3.1
CAS: 9029-86-1 |
|---|
