| Entry |
|
| Name |
formaldehyde transketolase;
dihydroxyacetone synthase |
| Class |
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
 |
| Sysname |
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase |
| Reaction(IUBMB) |
D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate +
glycerone [RN:R01440] |
| Reaction(KEGG) |
R01440;
(other) R06861 R06862
 |
| Substrate |
D-xylulose 5-phosphate [CPD:C00231];
formaldehyde [CPD:C00067] |
| Product |
glyceraldehyde 3-phosphate [CPD:C00118];
glycerone [CPD:C00184] |
| Cofactor |
Thiamin diphosphate [CPD:C00068] |
| Comment |
A thiamine-diphosphate protein. Not identical with EC 2.2.1.1
transketolase. Also converts hydroxypyruvate and formaldehyde into
glycerone and CO2. |
| Pathway |
PATH: ec00680 Methane metabolism |
Reference Authors Title
Journal
|
1 [PMID:7249920]
Bystrykh LV, Sokolov AP, Trotsenko IuA.
[Separation of transketolase and dihydroxyacetone synthase from
methylotrophic yeasts]
Dokl. Akad. Nauk. SSSR. 258 (1981) 499-501. |
Reference Authors Title
Journal Organism
|
2 [PMID:7074134]
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H.
Purification and properties of a transketolase responsible for
formaldehyde fixation in a methanol-utilizing yeast, candida
boidinii (Kloeckera sp.) No. 2201.
Biochim. Biophys. Acta. 715 (1982) 143-50.
Candida boidinii |
Reference Authors Title
Journal Organism
|
3 [PMID:6276498]
Waites MJ, Quayle JR.
The interrelation transketolase and dihydroxyacetone synthase
activities in the methylotrophic yeast Candida boidinii.
J. Gen. Microbiol. 124 (1981) 309-16.
Candida boidinii |
| Other DBs |
ExplorEnz - The Enzyme Database: 2.2.1.3
IUBMB Enzyme Nomenclature: 2.2.1.3
ExPASy - ENZYME nomenclature database: 2.2.1.3
BRENDA, the Enzyme Database: 2.2.1.3
CAS: 124566-23-0 |