KEGG   ENZYME: 2.2.1.3Help
Entry
EC 2.2.1.3                  Enzyme                                 

Name formaldehyde transketolase;
dihydroxyacetone synthase
Class Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
BRITE hierarchy
Sysname D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase
Reaction(IUBMB) D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate +
glycerone [RN:R01440]
Reaction(KEGG) R01440;
(other) R06861 R06862
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Substrate D-xylulose 5-phosphate [CPD:C00231];
formaldehyde [CPD:C00067]
Product glyceraldehyde 3-phosphate [CPD:C00118];
glycerone [CPD:C00184]
Cofactor Thiamin diphosphate [CPD:C00068]
Comment A thiamine-diphosphate protein. Not identical with EC 2.2.1.1
transketolase. Also converts hydroxypyruvate and formaldehyde into
glycerone and CO2.
Pathway PATH: ec00680  Methane metabolism
Reference
  Authors
  Title

  Journal
1  [PMID:7249920]
Bystrykh LV, Sokolov AP, Trotsenko IuA.
[Separation of transketolase and dihydroxyacetone synthase from
methylotrophic yeasts]
Dokl. Akad. Nauk. SSSR. 258 (1981) 499-501.
Reference
  Authors
  Title


  Journal
  Organism
2  [PMID:7074134]
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H.
Purification and properties of a transketolase responsible for
formaldehyde fixation in a methanol-utilizing yeast, candida
boidinii (Kloeckera sp.) No. 2201.
Biochim. Biophys. Acta. 715 (1982) 143-50.
Candida boidinii
Reference
  Authors
  Title

  Journal
  Organism
3  [PMID:6276498]
Waites MJ, Quayle JR.
The interrelation transketolase and dihydroxyacetone synthase
activities in the methylotrophic yeast Candida boidinii.
J. Gen. Microbiol. 124 (1981) 309-16.
Candida boidinii
Other DBs ExplorEnz - The Enzyme Database: 2.2.1.3
IUBMB Enzyme Nomenclature: 2.2.1.3
ExPASy - ENZYME nomenclature database: 2.2.1.3
BRENDA, the Enzyme Database: 2.2.1.3
CAS: 124566-23-0

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