KEGG   ENZYME: 2.3.1.-Help
Entry
EC 2.3.1.-                  Enzyme                                 
Class Transferases;
Acyltransferases;
Transferring groups other than amino-acyl groups
BRITE hierarchy
Reaction(IUBMB) (1) D-Alanine + Acetyl-CoA <=> 2-Amino-4-oxopentanoic acid + CoA
[RN:R00399];
(2) L-Lysine + Acetyl-CoA <=> N6-Acetyl-L-lysine + CoA [RN:R00454];
(3) 1H-Imidazole-4-ethanamine + Acetyl-CoA <=>
4-(beta-Acetylaminoethyl)imidazole + CoA [RN:R02152];
(4) n (R)-3-Hydroxybutanoyl-CoA <=> Poly-beta-hydroxybutyrate + n
CoA [RN:R04254];
(5) UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Acyl-carrier
protein <=> UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine +
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] [RN:R04550];
(6) 4-Hydroxyphenylacetyl-CoA + Glycine <=>
p-Hydroxyphenylacetylglycine + CoA [RN:R04777];
(7) Di[3-deoxy-D-manno-octulosonyl]-lipid A + Acyl-carrier protein
<=> Tetradecanoyl-[acp] + Lauroyl-KDO2-lipid IV(A) [RN:R05075];
(8) Lauroyl-KDO2-lipid IV(A) + Acyl-carrier protein <=>
Dodecanoyl-[acyl-carrier protein] +
Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) [RN:R05146];
(9) Benzoyl acetyl-CoA + CoA <=> S-Benzoate coenzyme A + Acetyl-CoA
[RN:R05506];
(10) 3-Oxopimeloyl-CoA + CoA <=> Glutaryl-CoA + Acetyl-CoA
[RN:R05586];
(11) Benzoylsuccinyl-CoA + CoA <=> S-Benzoate coenzyme A +
Succinyl-CoA [RN:R05587];
(12) Phenylacetyl-CoA + Glycine <=> Phenylacetylglycine + CoA
[RN:R05841];
(13) 2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoA <=>
3-Isopropylbut-3-enoyl-CoA + Propanoyl-CoA [RN:R06414];
(14) Chrysanthemin + p-Coumaroyl-CoA <=> Cyanidin
3-O-(6-O-p-coumaroyl)glucoside + CoA [RN:R06544];
(15) Cyanin + p-Coumaroyl-CoA <=> Cyanidin
3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside + CoA [RN:R06545];
(16) 4'''-Demalonylsalvianin + Malonyl-CoA <=> Salvianin + CoA
[RN:R06800];
(17) Naphthyl-2-oxomethyl-succinyl-CoA + CoA <=> 2-Naphthoyl-CoA +
Succinyl-CoA [RN:R06908];
(18) 1-(1-Alkenyl)-sn-glycero-3-phosphate + Acyl-CoA <=>
2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + CoA [RN:R07382];
(19) Glycosyl-4,4'-diaponeurosporenoate <=> Staphyloxanthin
[RN:R07656];
(20) Malonyl-CoA + Palmitoyl-CoA <=> 3-Oxostearoyl-CoA + CoA + CO2
[RN:R07758];
(21) Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=>
3-Oxostearoyl-[acp] + Acyl-carrier protein + CO2 [RN:R07762];
(22) 3-Hydroxy-5-oxohexanoyl-CoA + CoA <=> (S)-3-Hydroxybutanoyl-CoA
+ Acetyl-CoA [RN:R07833];
(23) Pelargonidin 3-O-glucoside + Caffeoyl-CoA <=> Pelargonidin
3-O-(6-caffeoyl-beta-D-glucoside) + CoA [RN:R07873];
(24) Pelargonin + Caffeoyl-CoA <=> Pelargonidin
3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + CoA
[RN:R07876];
(25) Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA
<=> Pelargonidin 3-O-3'',6''-O-dimalonylglucoside + CoA [RN:R07884];
(26) Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA <=>
Cyanidin 3-O-3'',6''-O-dimalonylglucoside + CoA [RN:R07885];
(27) Delphinidin 3-O-(6-O-malonyl-beta-D-glucoside) + Malonyl-CoA
<=> Delphinidin 3-O-3'',6''-O-dimalonylglucoside + CoA [RN:R07886];
(28) Albireodelphin <=> Gentiodelphin [RN:R07924];
(29) Delphinidin 3-O-glucoside + Caffeoyl-CoA <=> Delphinidin
3-O-(6-caffeoyl-beta-D-glucoside) + CoA [RN:R07926];
(30) Pelargonidin 3-O-glucoside + p-Coumaroyl-CoA <=> Pelargonidin
3-(6-p-coumaroyl)glucoside + CoA [RN:R07927];
(31) Chrysanthemin + Caffeoyl-CoA <=> Cyanidin
3-(6-p-caffeoyl)glucoside + CoA [RN:R07928];
(32) Delphinidin 3-O-glucoside + p-Coumaroyl-CoA <=> Delphinidin
3-(6-p-coumaroyl)glucoside + CoA [RN:R07929];
(33) 3'-N-Debenzoyltaxol + S-Benzoate coenzyme A <=> Paclitaxel +
CoA [RN:R08171];
(34) Ecgonine methyl ester + S-Benzoate coenzyme A <=> Cocaine + CoA
[RN:R08430];
(35) p-Coumaroyl-CoA + Malonyl-CoA <=> p-Coumaroyl-diketide-CoA +
CoA + CO2 [RN:R08805];
(36) Feruloyl-CoA + Malonyl-CoA <=> Feruloyl-diketide-CoA + CoA +
CO2 [RN:R08806];
(37) p-Coumaroyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=>
Bisdemethoxycurcumin + 2 CoA + CO2 [RN:R08807];
(38) p-Coumaroyl-diketide-CoA + Feruloyl-CoA + H2O <=>
Demethoxycurcumin + 2 CoA + CO2 [RN:R08808];
(39) Feruloyl-diketide-CoA + p-Coumaroyl-CoA + H2O <=>
Demethoxycurcumin + 2 CoA + CO2 [RN:R08809];
(40) Feruloyl-diketide-CoA + Feruloyl-CoA + H2O <=> Curcumin + 2 CoA
+ CO2 [RN:R08810];
(41) Amaranthin + 1-O-Feruloyl-beta-D-glucose <=> Celosianin II +
D-Glucose [RN:R08819];
(42) Betanin + 1-O-Feruloyl-beta-D-glucose <=> Lampranthin II +
D-Glucose [RN:R08823]
Substrate D-Alanine [CPD:C00133];
Acetyl-CoA [CPD:C00024];
L-Lysine [CPD:C00047];
1H-Imidazole-4-ethanamine [CPD:C00388];
(R)-3-Hydroxybutanoyl-CoA [CPD:C03561];
UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine [CPD:C04652];
Acyl-carrier protein [CPD:C00229];
4-Hydroxyphenylacetyl-CoA [CPD:C05338];
Glycine [CPD:C00037];
Di[3-deoxy-D-manno-octulosonyl]-lipid A [CPD:C06026];
Lauroyl-KDO2-lipid IV(A) [CPD:C06251];
Benzoyl acetyl-CoA [CPD:C07118];
CoA [CPD:C00010];
3-Oxopimeloyl-CoA [CPD:C06715];
Benzoylsuccinyl-CoA [CPD:C09820];
Phenylacetyl-CoA [CPD:C00582];
2,6-Dimethyl-5-methylene-3-oxo-heptanoyl-CoA [CPD:C11948];
Chrysanthemin [CPD:C08604];
p-Coumaroyl-CoA [CPD:C00223];
Cyanin [CPD:C08639];
4'''-Demalonylsalvianin [CPD:C12641];
Malonyl-CoA [CPD:C00083];
Naphthyl-2-oxomethyl-succinyl-CoA [CPD:C14119];
1-(1-Alkenyl)-sn-glycero-3-phosphate [CPD:C15646];
Acyl-CoA [CPD:C00040];
Glycosyl-4,4'-diaponeurosporenoate [CPD:C16147];
Palmitoyl-CoA [CPD:C00154];
Hexadecanoyl-[acp] [CPD:C05764];
Malonyl-[acyl-carrier protein] [CPD:C01209];
3-Hydroxy-5-oxohexanoyl-CoA [CPD:C16273];
Pelargonidin 3-O-glucoside [CPD:C12137];
Caffeoyl-CoA [CPD:C00323];
Pelargonin [CPD:C08725];
Pelargonidin 3-O-(6-O-malonyl-beta-D-glucoside) [CPD:C12642];
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) [CPD:C12643];
Delphinidin 3-O-(6-O-malonyl-beta-D-glucoside) [CPD:C16301];
Albireodelphin [CPD:C16354];
Delphinidin 3-O-glucoside [CPD:C12138];
3'-N-Debenzoyltaxol [CPD:C16524];
S-Benzoate coenzyme A [CPD:C00512];
Ecgonine methyl ester [CPD:C12448];
Feruloyl-CoA [CPD:C00406];
p-Coumaroyl-diketide-CoA [CPD:C17740];
H2O [CPD:C00001];
Feruloyl-diketide-CoA [CPD:C17741];
Amaranthin [CPD:C08537];
1-O-Feruloyl-beta-D-glucose [CPD:C17759];
Betanin [CPD:C08540]
Product 2-Amino-4-oxopentanoic acid [CPD:C03341];
CoA [CPD:C00010];
N6-Acetyl-L-lysine [CPD:C02727];
4-(beta-Acetylaminoethyl)imidazole [CPD:C05135];
Poly-beta-hydroxybutyrate [CPD:C06143];
UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine [CPD:C06022];
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] [CPD:C04688];
p-Hydroxyphenylacetylglycine [CPD:C05596];
Tetradecanoyl-[acp] [CPD:C05761];
Lauroyl-KDO2-lipid IV(A) [CPD:C06251];
Dodecanoyl-[acyl-carrier protein] [CPD:C05223];
Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) [CPD:C06025];
S-Benzoate coenzyme A [CPD:C00512];
Acetyl-CoA [CPD:C00024];
Glutaryl-CoA [CPD:C00527];
Succinyl-CoA [CPD:C00091];
Phenylacetylglycine [CPD:C05598];
3-Isopropylbut-3-enoyl-CoA [CPD:C11949];
Propanoyl-CoA [CPD:C00100];
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside [CPD:C12095];
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside [CPD:C12096];
Salvianin [CPD:C12647];
2-Naphthoyl-CoA [CPD:C14120];
2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate [CPD:C15647];
Staphyloxanthin [CPD:C16148];
3-Oxostearoyl-CoA [CPD:C16216];
CO2 [CPD:C00011];
3-Oxostearoyl-[acp] [CPD:C16219];
Acyl-carrier protein [CPD:C00229];
(S)-3-Hydroxybutanoyl-CoA [CPD:C01144];
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) [CPD:C16297];
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside
[CPD:C12640];
Pelargonidin 3-O-3'',6''-O-dimalonylglucoside [CPD:C16288];
Cyanidin 3-O-3'',6''-O-dimalonylglucoside [CPD:C16289];
Delphinidin 3-O-3'',6''-O-dimalonylglucoside [CPD:C16290];
Gentiodelphin [CPD:C08641];
Delphinidin 3-O-(6-caffeoyl-beta-D-glucoside) [CPD:C16367];
Pelargonidin 3-(6-p-coumaroyl)glucoside [CPD:C16368];
Cyanidin 3-(6-p-caffeoyl)glucoside [CPD:C16369];
Delphinidin 3-(6-p-coumaroyl)glucoside [CPD:C16370];
Paclitaxel [CPD:C07394];
Cocaine [CPD:C01416];
p-Coumaroyl-diketide-CoA [CPD:C17740];
Feruloyl-diketide-CoA [CPD:C17741];
Bisdemethoxycurcumin [CPD:C17743];
Demethoxycurcumin [CPD:C17742];
Curcumin [CPD:C10443];
Celosianin II [CPD:C08542];
D-Glucose [CPD:C00031];
Lampranthin II [CPD:C08552]
KEGG   ENZYME: 2.7.7.58Help
Entry
EC 2.7.7.58                 Enzyme                                 
Name (2,3-dihydroxybenzoyl)adenylate synthase;
2,3-dihydroxybenzoate-AMP ligase
Class Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname ATP:2,3-dihydroxybenzoate adenylyltransferase
Reaction(IUBMB) ATP + 2,3-dihydroxybenzoate = diphosphate +
(2,3-dihydroxybenzoyl)adenylate [RN:R01504]
Reaction(KEGG) R01504
Show
Substrate ATP [CPD:C00002];
2,3-dihydroxybenzoate [CPD:C00196]
Product diphosphate [CPD:C00013];
(2,3-dihydroxybenzoyl)adenylate [CPD:C04030]
Pathway PATH: ec01053  Biosynthesis of siderophore group nonribosomal
               peptides
Orthology KO: K02312  2,3-dihydroxybenzoate-AMP ligase
KO: K02363  enterobactin 2,3-dihydroxybenzoate-AMP ligase /
            S-dihydroxybenzoyltransferase
KO: K04776  vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase
Genes ECO: b0594(entE)
ECJ: JW0586(entE)
ECD: ECDH10B_0554(entE)
EBW: BWG_0467(entE)
ECE: Z0736(entE)
ECS: ECs0633(entE)
ECF: ECH74115_0679(entE)
ETW: ECSP_0648(entE)
ECG: E2348C_0496(entE)
ECC: c0681(entE)
ECI: UTI89_C0596(entE)
ECP: ECP_0626(entE)
ECV: APECO1_1455(entE)
ECW: EcE24377A_0614(entE)
ECX: EcHS_A0645(entE)
ECM: EcSMS35_0614(entE)
ECY: ECSE_0661(entE)
ECL: EcolC_3050(entE)
ECK: EC55989_0586(entE)
ECQ: ECED1_0591(entE)
ECR: ECIAI1_0578(entE)
ECT: ECIAI39_0571(entE)
ECZ: ECS88_0633(entE)
EUM: ECUMN_0688(entE)
ELF: LF82_0567(entE)
EBL: B21_00550(entE)
EBD: ECBD_3060
EBR: ECB_00561(entE)
EOH: ECO103_0602(entE)
EOI: ECO111_0624(entE)
EOJ: ECO26_0669(entE)
EFE: EFER_2500(entE)
STY: STY0640(entE)
STT: t2272(entE)
SPT: SPA2138(entE)
SEK: SSPA1988(entE)
SPQ: SPAB_02967(entE)
SEI: SPC_0608(entE)
SEC: SC0627(entE)
SEH: SeHA_C0708(entE)
SEE: SNSL254_A0649(entE)
SEW: SeSA_A0754(entE)
SEA: SeAg_B0635(entE)
SED: SeD_A0692(entE)
SEG: SG0600(entE)
SET: SEN0565(entE)
SES: SARI_02340(entE)
STM: STM0596(entE)
SFL: SF0508(entE)
SFX: S0514(entE)
SFV: SFV_0542(entE)
SSN: SSON_0545(entE)
SBO: SBO_0455(entE)
SBC: SbBS512_E0496(entE)
SDY: SDY_0525(entE)
ECA: ECA0478(entE)
PCT: PC1_0463
PWA: Pecwa_0561
PLU: plu2729(entE)
PAY: PAU_00893(phbE)
ENT: Ent638_1126(entE)
ESA: ESA_00797(entE)
CTU: Ctu_30460(entE)
KPN: KPN_00612(entE)
KPE: KPK_3966(entE)
KPU: KP1_1558(entE)
CKO: CKO_02567(entE)
SPE: Spro_3420(entE)
DDA: Dd703_1489 Dd703_3074
DDC: Dd586_2818
DZE: Dd1591_1317
SML: Smlt2821
SMT: Smal_2275
VCH: VC0772
VCO: VC0395_A0301(vibE)
VCM: VCM66_0730(vibE)
VCJ: VCD_003554
VVU: VV2_0836 VV2_0840
VVY: VVA1301 VVA1306
VHA: VIBHAR_01399
PPR: PBPRA1662 PBPRB1823(entE)
PEN: PSEEN2505(pmsE)
AVN: Avin_21210(entE)
ACI: ACIAD2770(entE)
ACB: A1S_2381(entE) A1S_2574
ABY: ABAYE1096(entE)
ABC: ACICU_02578(entE)
ABN: AB57_2810(entE)
ABB: ABBFA_001062(entE)
SDE: Sde_3399
TTU: TERTU_4060(entE)
HCH: HCH_06564
MMW: Mmwyl1_1632(entE)
AHA: AHA_2478(entE)
ASA: ASA_1839(entE)
CVI: CV_1484(entE)
BAM: Bamb_1689
GEO: Geob_0224
MXA: MXAN_3645
SCL: sce3880(mxcE)
HOH: Hoch_2019
BME: BMEII0078(entE)
BMI: BMEA_B0017
BMF: BAB2_0014(entE)
BMB: BruAb2_0015(entE)
BMC: BAbS19_II00130(entE)
BMS: BRA0015(entE)
BMT: BSUIS_B0017(entE)
BOV: BOV_A0012(entE)
BCS: BCAN_B0017(entE)
BMR: BMI_II15(entE)
PDE: Pden_2386(entE)
BSU: BSU31980(dhbE)
BAN: BA2370(dhbE)
BAR: GBAA2370(dhbE)
BAA: BA_2864
BAT: BAS2206
BAH: BAMEG_2230(bacE)
BAI: BAA_2428(bacE)
BCE: BC2304
BCA: BCE_2400(dhbE)
BCZ: BCZK2129(entE)
BCR: BCAH187_A2470(bacE)
BCB: BCB4264_A2335(bacE)
BCU: BCAH820_2388(bacE)
BCG: BCG9842_B2990(bacE)
BCQ: BCQ_2296(dhbE)
BCX: BCA_2437(bacE)
BCY: Bcer98_1756
BTK: BT9727_2145(entE)
BTL: BALH_2109(entE)
BWE: BcerKBAB4_2177
BLI: BL04022(dhbE)
BLD: BLi03900(dhbE)
BAY: RBAM_029030(dhbE)
OIH: OB0956(dhbE)
GYM: GYMC10_4575
SEU: SEQ_1243(eqbD)
CKL: CKL_1504
CKR: CKR_1398
DSY: DSY2823
DHD: Dhaf_3967
APR: Apre_1763
CJK: jk1820(dhbE)
CKP: ckrop_1816
RHA: RHA1_ro04793
RER: RER_26980
ROP: ROP_48840
GBR: Gbro_2426
SCO: SCO7681(SC4C2.16c)
SGR: SGR_6732
TFU: Tfu_1871
TCU: Tcur_0365
SRO: Sros_3774
FRE: Franean1_3615 Franean1_5941
FAL: FRAAL4648
SEN: SACE_3853(dhbE)
SVI: Svir_20860
AMI: Amir_2726
STP: Strop_2803
GAU: GAU_3221
HAU: Haur_1803
Taxonomy
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:2531000]
Rusnak F, Faraci WS, Walsh CT.
Subcloning, expression, and purification of the enterobactin
biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration
of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product.
Biochemistry. 28 (1989) 6827-35.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 2.7.7.58
IUBMB Enzyme Nomenclature: 2.7.7.58
ExPASy - ENZYME nomenclature database: 2.7.7.58
BRENDA, the Enzyme Database: 2.7.7.58
CAS: 122332-73-4
DBGET integrated database retrieval system