| Entry |
|
|---|
| Name |
alkylglycerophosphate 2-O-acetyltransferase;
alkyllyso-GP:acetyl-CoA acetyltransferase |
|---|
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
|---|
| Sysname |
acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase |
|---|
| Reaction(IUBMB) |
acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate = CoA +
1-alkyl-2-acetyl-sn-glycero-3-phosphate [RN:R03455] |
|---|
| Reaction(KEGG) |
R03455
 |
|---|
| Substrate |
acetyl-CoA [CPD:C00024];
1-alkyl-sn-glycero-3-phosphate [CPD:C03968] |
|---|
| Product |
CoA [CPD:C00010];
1-alkyl-2-acetyl-sn-glycero-3-phosphate |
|---|
| Comment |
Involved in the biosynthesis of thrombocyte activating factor in
animal tissues. |
|---|
| Pathway |
PATH: ec00565 Ether lipid metabolism
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3007498]
Lee TC, Malone B, Snyder F.
A new de novo pathway for the formation of
1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating
factor. Biochemical characterization of
1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat
spleen.
J. Biol. Chem. 261 (1986) 5373-7.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.105
IUBMB Enzyme Nomenclature: 2.3.1.105
ExPASy - ENZYME nomenclature database: 2.3.1.105
BRENDA, the Enzyme Database: 2.3.1.105 |
|---|
