| Entry |
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| Name |
polysialic-acid O-acetyltransferase
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
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| Sysname |
acetyl-CoA:polysialic-acid O-acetyltransferase
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| Reaction(IUBMB) |
acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9 [RN: R04484 R07249]
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| Reaction(KEGG) |
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| Substrate |
acetyl-CoA [CPD: C00024];
alpha-2,8-linked polymer of sialic acid [CPD: C04466]
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| Product |
CoA [CPD: C00010];
polysialic acid acetylated at O-7 [CPD: C04505];
O-9
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| Comment |
Acts only on substrates containing more than 14 sialosyl residues. Catalyses the modification of capsular polysaccharides in some strains of Escherichia coli.
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| Reference |
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| Authors |
Higa HH, Varki A. |
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| Title |
Acetyl-coenzyme A:polysialic acid O-acetyltransferase from K1-positive Escherichia coli. The enzyme responsible for the O-acetyl plus phenotype and for O-acetyl form variation. |
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| Journal |
J. Biol. Chem. 263 (1988) 8872-8. |
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| Organism |
Escherichia coli [GN: eco] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 116412-21-6 |
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