KEGG   ENZYME: 2.3.1.137Help
Entry
EC 2.3.1.137                Enzyme                                 

Name
carnitine O-octanoyltransferase;
medium-chain/long-chain carnitine acyltransferase;
carnitine medium-chain acyltransferase;
easily solubilized mitochondrial carnitine palmitoyltransferase;
overt mitochondrial carnitine palmitoyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
octanoyl-CoA:L-carnitine O-octanoyltransferase
Reaction(IUBMB)
octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine [RN:R03779]
Reaction(KEGG)
Substrate
octanoyl-CoA [CPD:C01944];
L-carnitine [CPD:C00318]
Product
CoA [CPD:C00010];
L-octanoylcarnitine [CPD:C02838]
Comment
Acts on a range of acyl-CoAs, with optimal activity with C6 or C8 acyl groups. cf. EC 2.3.1.7 (carnitine O-acetyltransferase) and EC 2.3.1.21 (carnitine O-palmitoyltransferase).
History
EC 2.3.1.137 created 1992
Orthology
K05940  
carnitine O-octanoyltransferase
Genes
HSA: 
54677(CROT)
PTR: 
463514(CROT)
PPS: 
100977046(CROT)
GGO: 
101140286(CROT)
PON: 
100452848(CROT)
MCC: 
706186(CROT)
MMU: 
74114(Crot)
RNO: 
83842(Crot)
CGE: 
100750995(Crot)
HGL: 
101716437(Crot)
TUP: 
102478805(CROT)
CFA: 
482283(CROT)
AML: 
100475120(CROT)
FCA: 
101096799(CROT)
PTG: 
102972245(CROT)
BTA: 
281092(CROT)
BOM: 
102278173(CROT)
PHD: 
102328865(CROT)
CHX: 
102178596(CROT)
SSC: 
100521142(CROT)
CFR: 
102512006(CROT)
BACU: 
103003725(CROT)
LVE: 
103087959(CROT)
ECB: 
100050111(CROT)
MYB: 
102246466(CROT)
MYD: 
102755354(CROT)
PALE: 
102880644(CROT)
MDO: 
100027224(CROT)
SHR: 
100934458(CROT)
OAA: 
100077745(CROT)
GGA: 
420533(CROT)
MGP: 
TGU: 
100231530(CROT)
FAB: 
101816162(CROT)
PHI: 
102110439(CROT)
APLA: 
101793765(CROT)
FPG: 
101919746(CROT)
FCH: 
102049905(CROT)
CLV: 
102095452(CROT)
ASN: 
102386610(CROT)
AMJ: 
PSS: 
102461470(CROT)
CMY: 
102941072(CROT)
ACS: 
PBI: 
XTR: 
733879(crot)
DRE: 
553204(crot)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102358236(CROT)
CMK: 
103181560(crot)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
PHU: 
CEL: 
CELE_T20B3.1(T20B3.1)
CBR: 
NVE: 
PIF: 
 » show all
Taxonomy
Reference
1  [PMID:6436243]
  Authors
Farrell SO, Fiol CJ, Reddy JK, Bieber LL.
  Title
Properties of purified carnitine acyltransferases of mouse liver peroxisomes.
  Journal
J. Biol. Chem. 259 (1984) 13089-95.
  Organism
Mus musculus
Reference
2  [PMID:3342008]
  Authors
Healy MJ, Kerner J, Bieber LL.
  Title
Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?
  Journal
Biochem. J. 249 (1988) 231-7.
  Organism
Rattus norvegicus
Reference
3  [PMID:6630173]
  Authors
Miyazawa S, Ozasa H, Osumi T, Hashimoto T.
  Title
Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver.
  Journal
J. Biochem. (Tokyo). 94 (1983) 529-42.
  Organism
Rattus norvegicus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
39369-19-2

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