| Entry |
|
|---|
| Name |
platelet-activating factor acetyltransferase;
PAF acetyltransferase |
|---|
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
|---|
| Sysname |
1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glyce
ro-3-phospholipid acetyltransferase |
|---|
| Reaction(IUBMB) |
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine +
1-organyl-2-lyso-sn-glycero-3-phospholipid =
1-organyl-2-lyso-sn-glycero-3-phosphocholine +
1-alkyl-2-acetyl-sn-glycero-3-phospholipid [RN:R04722] |
|---|
| Reaction(KEGG) |
R04722
 |
|---|
| Substrate |
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine;
1-organyl-2-lyso-sn-glycero-3-phospholipid [CPD:C05217] |
|---|
| Product |
1-organyl-2-lyso-sn-glycero-3-phosphocholine [CPD:C04317];
1-alkyl-2-acetyl-sn-glycero-3-phospholipid [CPD:C05218] |
|---|
| Comment |
Catalyses the transfer of the acetyl group from
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating
factor) to the sn-2 position of lyso-glycerophospholipids containing
ethanolamine, choline, serine, inositol or phosphate groups at the
sn-3 position as well as to sphingosine and long-chain fatty
alcohols. The organyl group can be alkyl, acyl or alk-1-enyl
(sometimes also collectively referred to as 'radyl'). |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:1400315]
Lee TC, Uemura Y, Snyder F.
A novel CoA-independent transacetylase produces the ethanolamine
plasmalogen and acyl analogs of platelet-activating factor (PAF)
with PAF as the acetate donor in HL-60 cells.
J. Biol. Chem. 267 (1992) 19992-20001.
Bos taurus [GN:bta] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.149
IUBMB Enzyme Nomenclature: 2.3.1.149
ExPASy - ENZYME nomenclature database: 2.3.1.149
BRENDA, the Enzyme Database: 2.3.1.149
CAS: 9012-30-0 |
|---|
