| Entry |
|
|---|
| Name |
10-deacetylbaccatin III 10-O-acetyltransferase |
|---|
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
|---|
| Sysname |
acetyl-CoA:taxan-10beta-ol O-acetyltransferase |
|---|
| Reaction(IUBMB) |
acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III
[RN:R06311] |
|---|
| Reaction(KEGG) |
R06311
 |
|---|
| Substrate |
acetyl-CoA [CPD:C00024];
10-deacetylbaccatin III [CPD:C11700] |
|---|
| Product |
CoA [CPD:C00010];
baccatin III [CPD:C11900] |
|---|
| Comment |
The enzyme will not acylate the hydroxy group at 1beta, 7beta or
13alpha of 10-deacetyl baccatin III, or at 5alpha of
taxa-4(20),11-dien-5alpha-ol. May be identical to EC 2.3.1.163,
10-hydroxytaxane O-acetyltransferase. |
|---|
| Pathway |
PATH: ec00904 Diterpenoid biosynthesis
PATH: ec01062 Biosynthesis of terpenoids and steroids
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K12926 10-deacetylbaccatin III 10-O-acetyltransferase |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:10639122]
Walker K, Croteau R.
Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl
transferase cDNA from Taxus and functional expression in Escherichia
coli.
Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 583-7.
Taxus cuspidata |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.167
IUBMB Enzyme Nomenclature: 2.3.1.167
ExPASy - ENZYME nomenclature database: 2.3.1.167
BRENDA, the Enzyme Database: 2.3.1.167
CAS: 220946-63-4 |
|---|
