KEGG   ENZYME: 2.3.1.174Help
Entry
EC 2.3.1.174                Enzyme                                 

Name
3-oxoadipyl-CoA thiolase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
succinyl-CoA:acetyl-CoA C-succinyltransferase
Reaction(IUBMB)
succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA [RN:R00829]
Reaction(KEGG)
Substrate
succinyl-CoA [CPD:C00091];
acetyl-CoA [CPD:C00024]
Product
CoA [CPD:C00010];
3-oxoadipyl-CoA [CPD:C02232]
Comment
The enzyme from the bacterium Escherichia coli also has the activity of EC 2.3.1.223 (3-oxo-5,6-dehydrosuberyl-CoA thiolase).
History
EC 2.3.1.174 created 2005, modified 2013
Pathway
Benzoate degradation
Microbial metabolism in diverse environments
Orthology
K07823  
3-oxoadipyl-CoA thiolase
Genes
XCC: 
XCC0366(pcaF)
XCB: 
XCA: 
XCP: 
XCR_4149(pcaF)
XCV: 
XCV0380(pcaF)
XAC: 
XAC0366(pcaF)
XCI: 
XAX: 
XACM_0354(pcaF)
XAO: 
XOO: 
XOO0481(pcaF)
XOM: 
XOP: 
PXO_02905(pcaF)
XOR: 
XOC_4546(pcaF)
XAL: 
XALc_3031(pcaF)
XFU: 
RHD: 
PAE: 
PA0228(pcaF)
PAEV: 
N297_234(pcaF)
PAU: 
PAP: 
PAG: 
PAF: 
PNC: 
PDK: 
PSG: 
PRP: 
PAEP: 
PAER: 
PAEM: 
PAEL: 
PAES: 
PAEU: 
PAEG: 
PAEC: 
M802_233(pcaF)
PPU: 
PP_1377(pcaF)
PPF: 
PPG: 
PPW: 
PPT: 
PPB: 
PPI: 
PPX: 
T1E_0234(pcaF)
PPUH: 
PPUT: 
PPUN: 
PP4_09250(pcaF)
PPUU: 
PST: 
PSB: 
PSYR: 
PSP: 
PCI: 
PFL: 
PFL_1319(pcaF)
PPRC: 
PFO: 
PFS: 
PFLU1365(pcaF)
PFE: 
PFC: 
PPZ: 
PEN: 
PSEEN1165(pcaF)
PMK: 
PSA: 
PST_1256(pcaF)
PSZ: 
PSR: 
PSC: 
PSJ: 
PSH: 
PBA: 
PFV: 
PDR: 
PRE: 
PSV: 
PSK: 
PMON: 
PMOT: 
PKC: 
PKB_2950(pcaF)
AVN: 
AVL: 
AVD: 
ACI: 
ACIAD1450(catF)
SUR: 
BJA: 
blr0925(pcaF)
BJU: 
BRA: 
BBT: 
BRS: 
S23_68870(pcaF)
AOL: 
RPA: 
RPA0513(pcaF)
RPB: 
RPD: 
RPE: 
RPT: 
RPX: 
MET: 
MNO: 
CCR: 
CCS: 
NPP: 
SWI: 
SPHM: 
SCH: 
SSY: 
SLG_28040(pcaF)
ABA: 
SGN: 
SGRA_1421(pcaF)
 » show all
Taxonomy
Reference
1  [PMID:11741862]
  Authors
Kaschabek SR, Kuhn B, Muller D, Schmidt E, Reineke W.
  Title
Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: purification and characterization of 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase.
  Journal
J. Bacteriol. 184 (2002) 207-15.
  Organism
Pseudomonas sp.
  Sequence
Reference
2  [PMID:11741863]
  Authors
Gobel M, Kassel-Cati K, Schmidt E, Reineke W.
  Title
Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: cloning, characterization, and analysis of sequences encoding 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase.
  Journal
J. Bacteriol. 184 (2002) 216-23.
  Organism
Pseudomonas sp.
  Sequence
Reference
3  [PMID:20660314]
  Authors
Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G
  Title
Bacterial phenylalanine and phenylacetate catabolic pathway revealed.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 107 (2010) 14390-5.
  Organism
Escherichia coli
  Sequence
[eco:b1397]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
403496-07-1

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