| Entry |
|
|---|
| Name |
1-acylglycerophosphocholine O-acyltransferase;
lysolecithin acyltransferase;
1-acyl-sn-glycero-3-phosphocholine acyltransferase;
acyl coenzyme A-monoacylphosphatidylcholine acyltransferase;
acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase;
lysophosphatide acyltransferase;
lysophosphatidylcholine acyltransferase |
|---|
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
|---|
| Sysname |
acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase |
|---|
| Reaction(IUBMB) |
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA +
1,2-diacyl-sn-glycero-3-phosphocholine [RN:R01318] |
|---|
| Reaction(KEGG) |
R01318;
(other) R04480
 |
|---|
| Substrate |
acyl-CoA [CPD:C00040];
1-acyl-sn-glycero-3-phosphocholine [CPD:C04230] |
|---|
| Product |
CoA [CPD:C00010];
1,2-diacyl-sn-glycero-3-phosphocholine [CPD:C00157] |
|---|
| Comment |
Acts preferentially with unsaturated acyl-CoA derivatives.
1-Acyl-sn-glycero-3-phosphoinositol can also act as acceptor. |
|---|
| Pathway |
PATH: ec00564 Glycerophospholipid metabolism |
|---|
Reference
Authors
Title
Journal
|
1 [PMID:6250446]
Bell RM, Coleman RA.
Enzymes of glycerolipid synthesis in eukaryotes.
Annu. Rev. Biochem. 49 (1980) 459-87. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:5661029]
Hill EE, Lands WE.
Incorporation of long-chain and polyunsaturated acids into
phosphatidate and phosphatidylcholine.
Biochim. Biophys. Acta. 152 (1968) 645-8.
Rattus norvegicus [GN:rno], Cavia porcellus |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:598375]
Miki Y, Hosaka K, Yamashita S, Handa H, Numa S.
Acyl-acceptor specificities of 1-acylglycerolphosphate
acyltransferase and 1-acylglycerophosphorylcholine acyltransferase
resolved from rat liver microsomes.
Eur. J. Biochem. 81 (1977) 433-41.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:6078124]
van den Bosch H, van Golde LM, Eibl H, van Deenen LL.
The acylation of 1-acylglycero-3-phosphorylcholines by rat-liver
microsomes.
Biochim. Biophys. Acta. 144 (1967) 613-23.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.23
IUBMB Enzyme Nomenclature: 2.3.1.23
ExPASy - ENZYME nomenclature database: 2.3.1.23
BRENDA, the Enzyme Database: 2.3.1.23
CAS: 9027-64-9 |
|---|
