KEGG   ENZYME: 2.3.1.42Help
Entry
EC 2.3.1.42                 Enzyme                                 
Name
glycerone-phosphate O-acyltransferase;
dihydroxyacetone phosphate acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:glycerone-phosphate O-acyltransferase
Reaction(IUBMB)
acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate [RN:R01013]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
glycerone phosphate [CPD:C00111]
Product
CoA [CPD:C00010];
acylglycerone phosphate [CPD:C03372]
Comment
A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.
Pathway
Glycerophospholipid metabolism
Orthology
K00649  
glyceronephosphate O-acyltransferase
K13507  
glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase
Genes
HSA: 
8443(GNPAT)
PTR: 
741681(GNPAT)
PPS: 
100994430(GNPAT)
GGO: 
101145496(GNPAT)
PON: 
100172931(GNPAT)
MCC: 
713603(GNPAT)
MMU: 
14712(Gnpat)
RNO: 
84470(Gnpat)
CFA: 
479204(GNPAT)
AML: 
FCA: 
101090468(GNPAT)
BTA: 
538800(GNPAT)
SSC: 
100156253(GNPAT)
ECB: 
100060758(GNPAT)
MDO: 
100029521(GNPAT)
SHR: 
100934097(GNPAT)
OAA: 
100085042
GGA: 
421548(GNPAT)
MGP: 
100543913
TGU: 
100224202(GNPAT)
ACS: 
100562202(gnpat)
XLA: 
444573
XTR: 
733943(gnpat)
DRE: 
572335(gnpat)
TRU: 
101062802
OLA: 
101155817
BFO: 
BRAFLDRAFT_71820
CIN: 
100178961
SPU: 
590838
DME: 
Dmel_CG4625(Dhap-at)
DPO: 
Dpse_GA18312
DAN: 
Dana_GF17273
DER: 
Dere_GG12243
DPE: 
Dper_GL21684
DSE: 
Dsec_GM10240
DSI: 
Dsim_GD18193
DWI: 
Dwil_GK13976
DYA: 
Dyak_GE10692
DGR: 
Dgri_GH18612
DMO: 
Dmoj_GI10360
DVI: 
Dvir_GJ10212
AGA: 
AgaP_AGAP001908
AAG: 
AaeL_AAEL012743
CQU: 
CpipJ_CPIJ013939 CpipJ_CPIJ019914
AME: 
412563(Dhap-at)
NVI: 
100115025(NV16066)
TCA: 
660119
API: 
100573870
PHU: 
Phum_PHUM546060
ISC: 
IscW_ISCW018554
CEL: 
CELE_Y46G5A.21(acl-7)
CBR: 
CBG18430(Cbr-acl-7)
BMY: 
Bm1_40215
NVE: 
NEMVE_v1g174806
HMG: 
100205381
TAD: 
TRIADDRAFT_57210
AQU: 
100640070
SCE: 
YBL011W(SCT1) YKR067W(GPT2)
AGO: 
AGOS_AFR489W AGOS_AGR301C
ERC: 
Ecym_1433 Ecym_5484
KLA: 
KLLA0B10538g KLLA0F16104g
LTH: 
KLTH0E07458g KLTH0F17160g
PPA: 
PAS_chr1-3_0081 PAS_chr3_0073
VPO: 
Kpol_1025p48 Kpol_473p9
ZRO: 
ZYRO0B15708g ZYRO0G09834g
CGR: 
CAGL0E02849g CAGL0K08162g
NCS: 
NCAS_0B06810(NCAS0B06810) NCAS_0C05390(NCAS0C05390)
NDI: 
NDAI_0A03280(NDAI0A03280) NDAI_0H00720(NDAI0H00720)
TPF: 
TPHA_0J01260(TPHA0J01260) TPHA_0K01680(TPHA0K01680)
TBL: 
TBLA_0C04170(TBLA0C04170) TBLA_0J00910(TBLA0J00910)
TDL: 
TDEL_0B02750(TDEL0B02750) TDEL_0F02510(TDEL0F02510)
KAF: 
KAFR_0H00490(KAFR0H00490) KAFR_0I01020(KAFR0I01020)
DHA: 
DEHA2A08624g DEHA2E07040g
PIC: 
PICST_45343 PICST_81897(SCT1)
PGU: 
PGUG_03525 PGUG_05538
LEL: 
LELG_00726 LELG_02141
CAL: 
CaO19.1289(SCT1) CaO19.13237(GPT2) CaO19.5815(GPT2)
CTP: 
CTRG_01364 CTRG_02630
CDU: 
CD36_17480 CD36_80750
COT: 
CORT_0A09980 CORT_0B03620
YLI: 
YALI0C00209g
CLU: 
CLUG_01349 CLUG_05540
NCR: 
NCU05985
SMP: 
SMAC_07913
PAN: 
PODANSg3091
TTT: 
THITE_2109967
MTM: 
MYCTH_2306608
MGR: 
MGG_01291
FGR: 
FG08766.1
NHE: 
NECHADRAFT_67309
VAL: 
VDBG_08044
SSL: 
SS1G_00327
BFU: 
BC1G_00805
ANI: 
AN5599.2
NFI: 
NFIA_104820
AFM: 
AFUA_4G11360
AOR: 
AOR_1_1460114(AO090701000835) AOR_1_1930154(AO090003001084)
ANG: 
ANI_1_490124(An14g03360)
AFV: 
AFLA_027370 AFLA_062900
ACT: 
ACLA_050450
PCS: 
Pc22g05820
CIM: 
CIMG_01558 CIMG_03543
CPW: 
CPC735_007100 CPC735_049030
PBL: 
PAAG_02695
URE: 
UREG_05274 UREG_07333
ABE: 
ARB_02331
TVE: 
TRV_04690
AJE: 
HCAG_01573 HCAG_06726
PNO: 
SNOG_06316
PTE: 
PTT_06646
ZTR: 
MYCGRDRAFT_56708
TML: 
GSTUM_00005844001
SPO: 
SPBC1718.04
CNE: 
CNC02160
CNB: 
CNBC5070
CGI: 
CGB_C3270C
LBC: 
LACBIDRAFT_171034(G3PAT-3)
MPR: 
MPER_07994
CCI: 
CC1G_04274
SCM: 
SCHCODRAFT_14418
MGL: 
MGL_2378
PGR: 
PGTG_04652 PGTG_20364
MBR: 
MONBRDRAFT_14444
NGR: 
NAEGRDRAFT_72483
DDI: 
DDB_G0289081
DPP: 
DICPUDRAFT_54421
PTM: 
GSPATT00011146001
TBR: 
Tb10.70.4400 Tb927.4.3160(Tb04.2H8.550)
TCR: 
504867.90 510943.150
LMA: 
LMJF_34_1090(DAT)
LIF: 
LINJ_03_0070(GAT) LINJ_34_1170(DAT)
LDO: 
LDBPK_030070 LDBPK_341170
LMI: 
LMXM_03_0080 LMXM_33_1090
LBZ: 
LBRM_03_0090 LBRM_20_1120(DAT)
PTI: 
PHATRDRAFT_54709(GPT1)
TPS: 
THAPSDRAFT_262127 THAPSDRAFT_4704
PIF: 
PITG_18707
 » show all
Taxonomy
Reference
1  [PMID:6271231]
  Authors
Ballas LM, Bell RM.
  Title
Topography of glycerolipid synthetic enzymes. Synthesis of phosphatidylserine, phosphatidylinositol and glycerolipid intermediates occurs on the cytoplasmic surface of rat liver microsomal vesicles.
  Journal
Biochim. Biophys. Acta. 665 (1981) 586-95.
  Organism
Rattus norvegicus [GN:rno]
Reference
2  [PMID:6746639]
  Authors
Declercq PE, Haagsman HP, Van Veldhoven P, Debeer LJ, Van Golde LM, Mannaerts GP.
  Title
Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis.
  Journal
J. Biol. Chem. 259 (1984) 9064-75.
  Organism
Rattus norvegicus [GN:rno]
Reference
3  [PMID:5656381]
  Authors
Hajra AK.
  Title
Biosynthesis of acyl dihydroxyacetone phosphate in guinea pig liver mitochondria.
  Journal
J. Biol. Chem. 243 (1968) 3458-65.
  Organism
Cavia porcellus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37257-19-5
DBGET integrated database retrieval system