| Entry |
|
|---|
| Name |
glycerone-phosphate O-acyltransferase;
dihydroxyacetone phosphate acyltransferase |
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
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| Sysname |
acyl-CoA:glycerone-phosphate O-acyltransferase |
|---|
| Reaction(IUBMB) |
acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate
[RN:R01013] |
|---|
| Reaction(KEGG) |
R01013
 |
|---|
| Substrate |
acyl-CoA [CPD:C00040];
glycerone phosphate [CPD:C00111] |
|---|
| Product |
CoA [CPD:C00010];
acylglycerone phosphate [CPD:C03372] |
|---|
| Comment |
A membrane protein. Uses CoA derivatives of palmitate, stearate and
oleate, with highest activity on palmitoyl-CoA. |
|---|
| Pathway |
PATH: ec00564 Glycerophospholipid metabolism |
|---|
| Orthology |
KO: K00649 glyceronephosphate O-acyltransferase |
|---|
| Genes |
HSA: 8443(GNPAT)
PTR: 741681(GNPAT)
MCC: 713603(GNPAT)
MMU: 14712(Gnpat)
RNO: 84470(Gnpat)
CFA: 479204(GNPAT)
BTA: 538800(GNPAT)
SSC: 100156253(GNPAT)
ECB: 100060758
MDO: 100029521
OAA: 100085042
GGA: 421548(GNPAT)
TGU: 100224202
XLA: 444573
XTR: 733943
DRE: 572335(gnpat)
CIN: 100178961
SPU: 590838
DME: Dmel_CG4625(Dhap-at)
DPO: Dpse_GA18312
DAN: Dana_GF17273
DER: Dere_GG12243
DPE: Dper_GL21684
DSE: Dsec_GM10240
DSI: Dsim_GD18193
DYA: Dyak_GE10692
DGR: Dgri_GH18612
DMO: Dmoj_GI10360
AGA: AgaP_AGAP001908
AAG: AaeL_AAEL012743
CQU: CpipJ_CPIJ013939 CpipJ_CPIJ019914
NVI: 100115025
TCA: 660119
ISC: IscW_ISCW018554
CEL: Y46G5A.21(acl-7)
BMY: Bm1_40215
NVE: NEMVE_v1g174806
TAD: TRIADDRAFT_57210
DDI: DDBDRAFT_0188248
PTM: GSPATT00011146001
TBR: Tb927.4.3160
LMA: LmjF34.1090
LIF: LinJ34.1010
LBZ: LbrM20_V2.1120
 |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:6271231]
Ballas LM, Bell RM.
Topography of glycerolipid synthetic enzymes. Synthesis of
phosphatidylserine, phosphatidylinositol and glycerolipid
intermediates occurs on the cytoplasmic surface of rat liver
microsomal vesicles.
Biochim. Biophys. Acta. 665 (1981) 586-95.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6746639]
Declercq PE, Haagsman HP, Van Veldhoven P, Debeer LJ, Van Golde LM,
Mannaerts GP.
Rat liver dihydroxyacetone-phosphate acyltransferases and their
contribution to glycerolipid synthesis.
J. Biol. Chem. 259 (1984) 9064-75.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:5656381]
Hajra AK.
Biosynthesis of acyl dihydroxyacetone phosphate in guinea pig liver
mitochondria.
J. Biol. Chem. 243 (1968) 3458-65.
Cavia porcellus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.42
IUBMB Enzyme Nomenclature: 2.3.1.42
ExPASy - ENZYME nomenclature database: 2.3.1.42
BRENDA, the Enzyme Database: 2.3.1.42
CAS: 37257-19-5 |
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