KEGG   ENZYME: 2.3.1.52Help
Entry
EC 2.3.1.52                 Enzyme                                 

Name
2-acylglycerol-3-phosphate O-acyltransferase;
2-acylglycerophosphate acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase
Reaction(IUBMB)
acyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02242]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
2-acyl-sn-glycerol 3-phosphate [CPD:C03974]
Product
CoA [CPD:C00010];
1,2-diacyl-sn-glycerol 3-phosphate [CPD:C00416]
Comment
Saturated acyl-CoA thioesters are the most effective acyl donors.
History
EC 2.3.1.52 created 1976
Pathway
Glycerophospholipid metabolism
Reference
1  [PMID:4774123]
  Authors
Yamashita S, Hosaka K, Numa S.
  Title
Acyl-donor specificities of partially purified 1-acylglycerophosphate acyltransferase, 2-acylglycerophosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes.
  Journal
Eur. J. Biochem. 38 (1973) 25-31.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
51901-17-8

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