KEGG   ENZYME: 2.3.1.7Help
Entry
EC 2.3.1.7                  Enzyme                                 
Name carnitine O-acetyltransferase;
acetyl-CoA-carnitine O-acetyltransferase;
acetylcarnitine transferase;
carnitine acetyl coenzyme A transferase;
carnitine acetylase;
carnitine acetyltransferase;
carnitine-acetyl-CoA transferase;
CATC
Class Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname acetyl-CoA:carnitine O-acetyltransferase
Reaction(IUBMB) acetyl-CoA + carnitine = CoA + O-acetylcarnitine [RN:R02396]
Reaction(KEGG) R02396
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Substrate acetyl-CoA [CPD:C00024];
carnitine [CPD:C00487]
Product CoA [CPD:C00010];
O-acetylcarnitine [CPD:C02571]
Comment Also acts on propanoyl-CoA and butanoyl-CoA (cf. EC 2.3.1.21
carnitine O-palmitoyltransferase and EC 2.3.1.137 carnitine
O-octanoyltransferase).
Orthology KO: K00624  carnitine O-acetyltransferase
Genes HSA: 1384(CRAT)
PTR: 464783(CRAT)
MCC: 716908
MMU: 12908(Crat)
RNO: 311849(Crat)
CFA: 491304(CRAT)
BTA: 512902(CRAT)
SSC: 100127351(CRAT)
ECB: 100070062(CRAT)
MDO: 100012605
GGA: 417195(CRAT)
TGU: 100231079
XLA: 443922
XTR: 394811(crat) 613081
DRE: 447855(crat) 449545
BFO: BRAFLDRAFT_83552
CIN: 100177217
SPU: 593866
DME: Dmel_CG1041 Dmel_CG5122 Dmel_CG5265
DPO: Dpse_GA18675 Dpse_GA28753
DAN: Dana_GF14219
DER: Dere_GG10489 Dere_GG22082 Dere_GG23813
DPE: Dper_GL21173 Dper_GL24737
DSE: Dsec_GM10135 Dsec_GM15216
DSI: Dsim_GD19146 Dsim_GD19548 Dsim_GD23864
DYA: Dyak_GE10114 Dyak_GE18615 Dyak_GE24102
DGR: Dgri_GH13284 Dgri_GH13285
DMO: Dmoj_GI17475 Dmoj_GI17476
AAG: AaeL_AAEL011355
CQU: CpipJ_CPIJ019087
NVI: 100118112
TCA: 659316
ISC: IscW_ISCW004720
CEL: B0395.3
CBR: CBG16408
NVE: NEMVE_v1g163430 NEMVE_v1g203043
HMG: 100207901
TAD: TRIADDRAFT_20587
SCE: YAR035W(YAT1) YML042W(CAT2)
AGO: AGOS_AAR124C AGOS_AER224W
KLA: KLLA0A02123g KLLA0C04169g
LTH: KLTH0G03300g
DHA: DEHA0D10087g DEHA0D19525g
PIC: PICST_34304(CAT2) PICST_68034(YAT1)
PPA: PAS_chr1-4_0074 PAS_chr3_0069
VPO: Kpol_1045p53 Kpol_286p3
LEL: LELG_01331 LELG_04352
ZRO: ZYRO0A05236g ZYRO0D12144g
CAL: CaO19.12026(YAT1) CaO19.12060(CAT2)
CTP: CTRG_00243 CTRG_04354
CDU: CD36_01580 CD36_41910(CAT2)
CGR: CAGL0C05027g CAGL0J11836g
YLI: YALI0B10340g YALI0F21197g
NCR: NCU01611 NCU08002
PAN: PODANSg6605 PODANSg7409
MGR: MGG_01721 MGG_06981
FGR: FG00840.1 FG01924.1
ANI: AN1059.2 AN6279.2
AFM: AFUA_1G12340 AFUA_2G12530
AOR: AO090001000295 AO090026000404
ANG: An08g04990 An18g01590
AFV: AFLA_067010 AFLA_135240
PCS: Pc13g13280 Pc20g15010
NFI: NFIA_013190 NFIA_087670
CIM: CIMG_05196 CIMG_06895
URE: UREG_05953 UREG_06418
SSL: SS1G_01589 SS1G_13339
BFU: BC1G_02490 BC1G_14516
CNE: CNA05200 CNF04660
CNB: CNBA5020 CNBF0240
LBC: LACBIDRAFT_188234 LACBIDRAFT_189447
MPR: MPER_10246 MPER_12539
UMA: UM00789.1 UM01835.1
MGL: MGL_3429
TBR: Tb11.18.0006
TCR: 508355.40 511303.40
PTI: PHATRDRAFT_48078(CAT2) PHATRDRAFT_859
TPS: THAPSDRAFT_13065(CAT1_2) THAPSDRAFT_31762(CAT2)
PPR: PBPRB1741
CJA: CJA_3754
SSE: Ssed_1774
DNO: DNO_0679
MPN: MPN114(cpt2)
MPU: MYPU_7750(cat)
CUR: cur_1770
CKP: ckrop_0605
NFA: nfa31870
KRH: KRH_22440
TCU: Tcur_1929
FRA: Francci3_1063
FRE: Franean1_5392
FAL: FRAAL1805
SEN: SACE_3158
SVI: Svir_26670
STP: Strop_2064
SAQ: Sare_2208
Taxonomy
Structures PDB: 1NDB  1NDF  1NDI  1NM8  1S5O  1T7O  1T7Q  
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:14285260]
CHASE JF, PEARSON DJ, TUBBS PK.
THE PREPARATION OF CRYSTALLIN CARNITINE ACETYLTRANSFERASE.
Biochim. Biophys. Acta. 96 (1965) 162-5.
Sus scofa [GN:ssc], pigeon
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:13275966]
FRIEDMAN S, FRAENKEL G.
Reversible enzymatic acetylation of carnitine.
Arch. Biochem. Biophys. 59 (1955) 491-501.
pigeon
Reference
  Authors
  Title

  Journal
  Organism
 3  [PMID:6404901]
Miyazawa S, Ozasa H, Furuta S, Osumi T, Hashimoto T.
Purification and properties of carnitine acetyltransferase from rat
liver.
J. Biochem. 93 (1983) 439-51.
Rattus norvegicus [GN:rno]
Other DBs ExplorEnz - The Enzyme Database: 2.3.1.7
IUBMB Enzyme Nomenclature: 2.3.1.7
ExPASy - ENZYME nomenclature database: 2.3.1.7
BRENDA, the Enzyme Database: 2.3.1.7
CAS: 9029-90-7
DBGET integrated database retrieval system