| Entry |
|
| Name |
diacylglycerol---sterol O-acyltransferase;
1,2-diacyl-sn-glycerol:sterol acyl transferase |
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
| Sysname |
1,2-diacyl-sn-glycerol:sterol O-acyltransferase |
| Reaction(IUBMB) |
1,2-diacyl-sn-glycerol + sterol = monoacylglycerol + sterol ester
[RN:R02693] |
| Reaction(KEGG) |
R02693 > R02692
 |
| Substrate |
1,2-diacyl-sn-glycerol [CPD:C00641];
sterol [CPD:C00370] |
| Product |
monoacylglycerol [CPD:C01885];
sterol ester [CPD:C01958] |
| Comment |
Cholesterol, sitosterol, campesterol and diacylglycerol can act as
acceptors. Transfers a number of long-chain fatty acyl groups. |
| Pathway |
PATH: ec00100 Steroid biosynthesis |
Reference Authors Title Journal
|
1
Bartlett, K., Keat, M.J. and Mercer, E.I.
Biosynthesis of sterol esters in Phycomyces blakesleeanus.
Phytochemistry 13 (1974) 1107-1113. |
Reference Authors Title
Journal Organism
|
2 [PMID:742884]
Garcia RE, Mudd JB.
Metabolism of monoacylglycerol and diacylglycerol by enzyme
preparations from spinach leaves.
Arch. Biochem. Biophys. 191 (1978) 487-93.
Spinacia oleracea |
Reference Authors Title
Journal
|
3
Garcia, R.E. and Mudd, J.B.
1,2-Diacyl-sn-glycerol:sterol acyl transferase from spinach leaves
(Spinacia oleracea L.).
Methods Enzymol. 71 (1981) 768-772. |
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.73
IUBMB Enzyme Nomenclature: 2.3.1.73
ExPASy - ENZYME nomenclature database: 2.3.1.73
BRENDA, the Enzyme Database: 2.3.1.73
CAS: 79586-23-5 |