| Entry |
|
|---|
| Name |
cysteine-S-conjugate N-acetyltransferase |
|---|
| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
 |
|---|
| Sysname |
acetyl-CoA:S-substituted L-cysteine N-acetyltransferase |
|---|
| Reaction(IUBMB) |
acetyl-CoA + an S-substituted L-cysteine = CoA + an S-substituted
N-acetyl-L-cysteine [RN:R04950] |
|---|
| Reaction(KEGG) |
R04950
 |
|---|
| Substrate |
acetyl-CoA [CPD:C00024];
S-substituted L-cysteine [CPD:C05726] |
|---|
| Product |
CoA [CPD:C00010];
S-substituted N-acetyl-L-cysteine [CPD:C05727] |
|---|
| Comment |
S-Benzyl-L-cysteine and, in decreasing order of activity,
S-butyl-L-cysteine, S-propyl-L-cysteine, O-benzyl-L-serine and
S-ethyl-L-cysteine, can act as acceptors. |
|---|
| Pathway |
PATH: ec00480 Glutathione metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6892478]
Duffel MW, Jakoby WB.
Cysteine S-conjugate N-acetyltransferase from rat kidney microsomes.
Mol. Pharmacol. 21 (1982) 444-8.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.1.80
IUBMB Enzyme Nomenclature: 2.3.1.80
ExPASy - ENZYME nomenclature database: 2.3.1.80
BRENDA, the Enzyme Database: 2.3.1.80
CAS: 81725-80-6 |
|---|
