KEGG   ENZYME: 2.3.2.10Help
Entry
EC 2.3.2.10                 Enzyme                                 
Name UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase;
alanyl-transfer ribonucleate-uridine
diphosphoacetylmuramoylpentapeptide transferase;
UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase;
uridine diphosphoacetylmuramoylpentapeptide lysine
N6-alanyltransferase;
L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-
alanyl-D-alanine 6-N-alanyltransferase
Class Transferases;
Acyltransferases;
Aminoacyltransferases
BRITE hierarchy
Sysname L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-ala
nyl-D-alanine N6-alanyltransferase
Reaction(IUBMB) L-alanyl-tRNA +
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine
= tRNA +
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-
alanyl-D-alanine [RN:R04613]
Reaction(KEGG) R04613;
(other) R05031 R08779
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Substrate L-alanyl-tRNA [CPD:C00886];
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine
[CPD:C04702]
Product tRNA [CPD:C00066];
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-
alanyl-D-alanine [CPD:C04894]
Comment Also acts on L-seryl-tRNA.
Pathway PATH: ec00550  Peptidoglycan biosynthesis
Orthology KO: K05363  serine/alanine adding enzyme
Genes LLK: LLKF_2319(murM)
LLC: LACR_2372
LLM: llmg_2352(murM)
SPY: SPy_0616(murM) SPy_1205
SPZ: M5005_Spy_0511(murM) M5005_Spy_0920
SPM: spyM18_0683(femB) spyM18_1156
SPG: SpyM3_0435(murM.1) SpyM3_0846(murM.2)
SPS: SPs1046 SPs1420
SPH: MGAS10270_Spy0505(murM) MGAS10270_Spy1034
SPI: MGAS10750_Spy0530(murM) MGAS10750_Spy1069
SPJ: MGAS2096_Spy0523(murM) MGAS2096_Spy0979
SPK: MGAS9429_Spy0501(murM) MGAS9429_Spy1022
SPF: SpyM50878(murM) SpyM51352(murM)
SPA: M6_Spy0532 M6_Spy0909
SPB: M28_Spy0490(murM) M28_Spy0892
SOZ: Spy49_0518c(murM.1) Spy49_0951c(murM2)
SPN: SP_0615
SPD: SPD_0535(murM)
SPR: spr0540(murM)
SPW: SPCG_0575(murM)
SPX: SPG_0558
SNE: SPN23F_05540(murM)
SPV: SPH_0708
SNM: SP70585_0676
SJJ: SPJ_0566
SPP: SPP_0629
SNT: SPT_0640
SAG: SAG0509(fibA) SAG0510
SAN: gbs0555 gbs0556
SAK: SAK_0659 SAK_0660
SMU: SMU.717(murM)
STC: str1155(murM)
STL: stu1155(murM)
STE: STER_1112
SSA: SSA_0862(murM)
SGO: SGO_1623(murM)
SEQ: SZO_06490 SZO_09500
SEZ: Sez_1015(murM) Sez_1319(murM)
SEU: SEQ_1178 SEQ_1501
SUB: SUB0607(murM)
SDS: SDEG_0637(murM) SDEG_0947
EFA: EF2658
Taxonomy
Structures PDB: 1P4N  1XE4  1XF8  1XIX  
Reference
  Authors
  Title



  Journal
  Organism
 1  [PMID:4248527]
Plapp R, Strominger JL.
Biosynthesis of the peptidoglycan of bacterial cell walls. 18.
Purification and properties of L-alanyl transfer ribonucleic
acid-uridine diphosphate-N-acetylmuramyl-pentapeptide transferase
from Lactobacillus viridescens.
J. Biol. Chem. 245 (1970) 3675-82.
Lactobacillus viridescens
Other DBs ExplorEnz - The Enzyme Database: 2.3.2.10
IUBMB Enzyme Nomenclature: 2.3.2.10
ExPASy - ENZYME nomenclature database: 2.3.2.10
BRENDA, the Enzyme Database: 2.3.2.10
CAS: 37257-26-4
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