| Entry |
|
|---|
| Class |
Transferases;
Acyltransferases;
Acyl groups converted into alkyl on transfer
 |
|---|
| Reaction(IUBMB) |
(1) 4-Methylthio-2-oxobutanoic acid + Acetyl-CoA + H2O <=>
2-(2'-Methylthio)ethylmalic acid + CoA [RN:R08619];
(2) 2-Oxo-5-methylthiopentanoic acid + Acetyl-CoA + H2O <=>
2-(3'-Methylthio)propylmalic acid + CoA [RN:R08623];
(3) 2-Oxo-6-methylthiohexanoic acid + Acetyl-CoA + H2O <=>
2-(4'-Methylthio)butylmalic acid + CoA [RN:R08627];
(4) 2-Oxo-7-methylthioheptanoic acid + Acetyl-CoA + H2O <=>
2-(5'-Methylthio)pentylmalic acid + CoA [RN:R08631];
(5) 2-Oxo-8-methylthiooctanoic acid + Acetyl-CoA + H2O <=>
2-(6'-Methylthio)hexylmalic acid + CoA [RN:R08640];
(6) 2-Oxo-9-methylthiononanoic acid + Acetyl-CoA + H2O <=>
2-(7'-Methylthio)heptylmalic acid + CoA [RN:R08644];
(7) 2-Oxo acid + Acetyl-CoA + H2O <=> 2-Alkylmalic acid + CoA
[RN:R08680] |
|---|
| Substrate |
4-Methylthio-2-oxobutanoic acid [CPD:C01180];
Acetyl-CoA [CPD:C00024];
H2O [CPD:C00001];
2-Oxo-5-methylthiopentanoic acid [CPD:C17211];
2-Oxo-6-methylthiohexanoic acid [CPD:C17216];
2-Oxo-7-methylthioheptanoic acid [CPD:C17220];
2-Oxo-8-methylthiooctanoic acid [CPD:C17224];
2-Oxo-9-methylthiononanoic acid [CPD:C17228];
2-Oxo acid [CPD:C00161] |
|---|
| Product |
2-(2'-Methylthio)ethylmalic acid [CPD:C17210];
CoA [CPD:C00010];
2-(3'-Methylthio)propylmalic acid [CPD:C17214];
2-(4'-Methylthio)butylmalic acid [CPD:C17218];
2-(5'-Methylthio)pentylmalic acid [CPD:C17222];
2-(6'-Methylthio)hexylmalic acid [CPD:C17226];
2-(7'-Methylthio)heptylmalic acid [CPD:C17230];
2-Alkylmalic acid [CPD:C17263] |
|---|
