| Entry |
|
|---|
| Name |
2-hydroxyglutarate synthase;
2-hydroxyglutaratic synthetase;
2-hydroxyglutaric synthetase;
alpha-hydroxyglutarate synthase;
hydroxyglutarate synthase;
2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) |
|---|
| Class |
Transferases;
Acyltransferases;
Acyl groups converted into alkyl groups on transfer
 |
|---|
| Sysname |
propanoyl-CoA:glyoxylate C-propanoyltransferase
(thioester-hydrolysing, 2-carboxyethyl-forming) |
|---|
| Reaction(IUBMB) |
propanoyl-CoA + H2O + glyoxylate = 2-hydroxyglutarate + CoA
[RN:R00932] |
|---|
| Reaction(KEGG) |
R00932
 |
|---|
| Substrate |
propanoyl-CoA [CPD:C00100];
H2O [CPD:C00001];
glyoxylate [CPD:C00048] |
|---|
| Product |
2-hydroxyglutarate [CPD:C02630];
CoA [CPD:C00010] |
|---|
| Pathway |
PATH: ec00660 C5-Branched dibasic acid metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14491016]
REEVES HC, AJL SJ.
Alpha-hydroxyglutaric acid synthetase.
J. Bacteriol. 84 (1962) 186-7.
Escherichia coli [GN:eco] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.3.3.11
IUBMB Enzyme Nomenclature: 2.3.3.11
ExPASy - ENZYME nomenclature database: 2.3.3.11
BRENDA, the Enzyme Database: 2.3.3.11
CAS: 9024-02-6 |
|---|
