KEGG   ENZYME: 2.4.1.-Help
Entry
EC 2.4.1.-                  Enzyme                                 
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Reaction(IUBMB) (1) UDP-D-galactose + Galactan <=> Galactan + UDP [RN:R00506];
(2) GDP-mannose + Mannan(n) <=> GDP + Mannan(n+1) [RN:R00887];
(3) GDP-mannose + 1,4-beta-D-Mannan <=> GDP + 1,4-beta-D-Mannan
[RN:R00890];
(4) Glucosylceramide + UDP-D-galactose <=>
beta-D-Galactosyl-1,4-beta-D-glucosylceramide + UDP [RN:R03354];
(5) Galactosylceramide + UDP-D-galactose <=> Digalactosylceramide +
UDP [RN:R04016];
(6) GDP-mannose + N,N'-Diacetylchitobiosyldiphosphodolichol <=> GDP
+ alpha-D-Mannosylchitobiosyldiphosphodolichol [RN:R04331];
(7) 3-D-Glucosyl-1,2-diacylglycerol + UDP-glucose <=>
Diglucosyl-diacylglycerol + UDP [RN:R04377];
(8) 4-Hydroxyphenylethanol + UDP-glucose <=> Salidroside + UDP
[RN:R05083];
(9) 3-O-Mycarosylerythronolide B + dTDP <=> Erythronolide B +
dTDP-L-mycarose [RN:R05530];
(10) dTDP-D-desosamine + 3-O-Mycarosylerythronolide B <=>
Erythromycin D + dTDP [RN:R05531];
(11) UDP-N-acetyl-D-glucosamine + Galactosylgloboside <=> UDP +
G00102 [RN:R05902];
(12) UDP-D-galactose + G00102 <=> UDP + G00103 [RN:R05903];
(13) Dolichyl phosphate D-mannose + G00147 <=> Dolichyl phosphate +
G00148 [RN:R05921];
(14) UDP-D-galactose + Lc3Cer <=> UDP + Paragloboside [RN:R05977];
(15) UDP-D-galactose + G00077 <=> UDP + iso-nLc8Cer [RN:R06021];
(16) GDP-L-fucose + nLc5Cer <=> GDP + Type II B antigen [RN:R06027];
(17) UDP-D-galactose + nLc5Cer <=> UDP + nLc6Cer [RN:R06033];
(18) UDP-D-galactose + nLc7Cer <=> UDP + nLc8Cer [RN:R06097];
(19) UDP-D-galactose + G00072 <=> UDP + G00073 [RN:R06192];
(20) UDP-D-galactose + Type II A antigen <=> UDP + G00057
[RN:R06198];
(21) GDP-D-mannose + G10532(n) <=> GDP + G10532(n+1) [RN:R06213];
(22) GDP-L-fucose + V3Fuc-nLc6Cer <=> GDP + V3Fuc,III3Fuc-nLc6Cer
[RN:R06221];
(23) GDP-L-fucose + G00084 <=> GDP + G00085 [RN:R06222];
(24) GDP-L-fucose + G00085 <=> GDP + G00086 [RN:R06224];
(25) GDP-L-fucose + G00081 <=> GDP + G00082 [RN:R06227];
(26) GDP-L-fucose + nLc6Cer <=> GDP + III3Fuc-nLc6Cer [RN:R06230];
(27) Galactosylceramide + UDP-D-galactose <=> Ga2-Cer + UDP
[RN:R06234];
(28) GDP-D-mannose + G00004 <=> GDP + G00005 [RN:R06238];
(29) Dolichyl D-glucosyl phosphate + G00007 <=> Dolichyl phosphate +
G10598 [RN:R06262];
(30) Dolichyl D-glucosyl phosphate + G10598 <=> Dolichyl phosphate +
G10599 [RN:R06263];
(31) Dolichyl D-glucosyl phosphate + G10599 <=> Dolichyl phosphate +
G00008 [RN:R06264];
(32) Glucocerebroside + UDP-D-galactose <=> Lactosylceramide + UDP
[RN:R06276];
(33) Demethyllactenocin + dTDP-L-mycarose <=> Demethylmacrocin +
dTDP [RN:R06452];
(34) Chrysanthemin + UDP-glucose <=> Cyanin + UDP [RN:R06546];
(35) Cyanidin 3-O-(6-O-p-coumaroyl)glucoside <=> Cyanidin
3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside [RN:R06547];
(36) 100-1 + dTDP-D-olivose <=> Urdamycin B + dTDP [RN:R06660];
(37) Urdamycin G + dTDP-D-olivose <=> Urdamycin A + dTDP
[RN:R06668];
(38) Phenanthroviridone aglycon <=> Jadomycin B [RN:R06670];
(39) Premithramycinone + dTDP-D-olivose <=> Premithramycin A1 + dTDP
[RN:R06716];
(40) Chrysanthemin + UDP-L-rhamnose <=> Cyanidin 3-O-rutinoside +
UDP [RN:R06818];
(41) Zeaxanthin + 2 UDP-glucose <=> Zeaxanthin diglucoside + 2 UDP
[RN:R07574];
(42) UDP-N-acetyl-D-galactosamine + Sda antigen - related compound
<=> UDP + Sda antigen [RN:R07609];
(43) UDP-N-acetyl-D-galactosamine + G00025 <=> UDP + G13023
[RN:R07614];
(44) UDP-N-acetyl-D-galactosamine + G01977 <=> UDP + G13024
[RN:R07615];
(45) UDP-N-acetyl-D-galactosamine + G01941 <=> UDP + G13025
[RN:R07616];
(46) UDP-D-galactose + G00025 <=> UDP + G11136 [RN:R07617];
(47) UDP-N-acetyl-D-glucosamine + G13027 <=> UDP + G13026
[RN:R07619];
(48) UDP-N-acetyl-D-glucosamine + G13026 <=> UDP + G13028
[RN:R07621];
(49) UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G10818
[RN:R07622];
(50) UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G13030
[RN:R07623];
(51) UDP-N-acetyl-D-glucosamine + G10818 <=> UDP + G13029
[RN:R07624];
(52) UDP-N-acetyl-D-glucosamine + G13030 <=> UDP + G13029
[RN:R07625];
(53) UDP-D-galactose + G00031 <=> UDP + G00032 [RN:R07628];
(54) 4,4'-Diaponeurosporenic acid <=>
Glycosyl-4,4'-diaponeurosporenoate [RN:R07655];
(55) Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonin + UDP
[RN:R07874];
(56) Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) + UDP-glucose
<=> Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside)
5-O-beta-D-glucoside + UDP [RN:R07875];
(57) Pelargonidin 3-O-glucoside + UDP-glucose <=> Pelargonidin
3-O-sophoroside + UDP [RN:R07877];
(58) Chrysanthemin + UDP-glucose <=> Cyanidin 3-O-sophoroside + UDP
[RN:R07878];
(59) Delphinidin 3-O-glucoside + UDP-glucose <=> Delphinidin
3-O-sophoroside + UDP [RN:R07879];
(60) Delphinidin 3-O-glucoside + UDP-L-rhamnose <=> Tulipanin + UDP
[RN:R07903];
(61) Cyanidin <=> Cyanidin 5-O-glucoside [RN:R07908];
(62) Cyanidin 5-O-glucoside <=> Cyanin [RN:R07909];
(63) Delphinidin 3-O-glucoside + UDP-glucose <=> Delphin + UDP
[RN:R07911];
(64) Delphinidin
3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside + UDP-glucose
<=> Ternatin C5 + UDP [RN:R07914];
(65) Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + UDP-glucuronate
<=> Cyanidin-3-O-(6''-O-malonyl-2''-O-glucuronyl)glucoside + UDP
[RN:R07932];
(66) Naringenin chalcone + UDP-glucose <=> Phlorizin chalcone + UDP
[RN:R08013];
(67) Zeatin + UDP-glucose <=> trans-Zeatin-7-beta-D-glucoside + UDP
[RN:R08075];
(68) Dihydrozeatin + UDP-glucose <=> Dihydrozeatin-O-glucoside + UDP
[RN:R08076];
(69) Curcumin + UDP-glucose <=> Curcumin monoglucoside + UDP
[RN:R08813];
(70) Curcumin monoglucoside + UDP-glucose <=> Curcumin diglucoside +
UDP [RN:R08814];
(71) 2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + UDP-glucose <=>
cyclo-Dopa 5-O-glucoside + UDP [RN:R08816];
(72) cyclo-Dopa 5-O-glucoside + UDP-glucuronate <=>
cyclo-Dopa-glucuronylglucoside + UDP [RN:R08817];
(73) Betanidin + UDP-glucose <=> Betanin + UDP [RN:R08822];
(74) Betanin + UDP-glucuronate <=> Amaranthin + UDP [RN:R08824];
(75) Betanidin + UDP-glucose <=> Gomphrenin-I + UDP [RN:R08830];
(76)
alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol +
GDP-mannose <=> D-Mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid
+ GDP [RN:R08858]
Substrate UDP-D-galactose [CPD:C00052];
Galactan [CPD:C05796];
GDP-mannose [CPD:C00096];
Mannan [CPD:C00464];
1,4-beta-D-Mannan [CPD:C02492];
Glucosylceramide [CPD:C01190];
Galactosylceramide [CPD:C02686];
N,N'-Diacetylchitobiosyldiphosphodolichol [CPD:C04537];
3-D-Glucosyl-1,2-diacylglycerol [CPD:C04046];
UDP-glucose [CPD:C00029];
4-Hydroxyphenylethanol [CPD:C06044];
3-O-Mycarosylerythronolide B [CPD:C06630];
dTDP [CPD:C00363];
dTDP-D-desosamine [CPD:C11911];
UDP-N-acetyl-D-glucosamine [GL:G10610];
Galactosylgloboside [GL:G00097];
UDP-D-galactose [GL:G10609];
[GL:G00102];
Dolichyl phosphate D-mannose [GL:G10617];
[GL:G00147];
Lc3Cer [GL:G00036];
[GL:G00077];
GDP-L-fucose [GL:G10615];
nLc5Cer [GL:G00051];
nLc5Cer [GL:G00066];
nLc7Cer [GL:G00068];
[GL:G00072];
Type II A antigen [GL:G00054];
GDP-D-mannose [GL:G10614];
[GL:G10532];
V3Fuc-nLc6Cer [GL:G00089];
[GL:G00084];
[GL:G00085];
[GL:G00081];
nLc6Cer [GL:G00067];
Galactosylceramide [GL:G11121];
[GL:G00004];
Dolichyl D-glucosyl phosphate [GL:G10618];
[GL:G00007];
[GL:G10598];
[GL:G10599];
Glucocerebroside [GL:G10238];
Demethyllactenocin [CPD:C12003];
dTDP-L-mycarose [CPD:C11916];
Chrysanthemin [CPD:C08604];
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside [CPD:C12095];
100-1 [CPD:C12405];
dTDP-D-olivose [CPD:C11923];
Urdamycin G [CPD:C12414];
Phenanthroviridone aglycon [CPD:C12439];
Premithramycinone [CPD:C12383];
UDP-L-rhamnose [CPD:C02199];
Zeaxanthin [CPD:C06098];
UDP-N-acetyl-D-galactosamine [GL:G10611];
Sda antigen - related compound [GL:G00850];
[GL:G00025];
[GL:G01977];
[GL:G01941];
[GL:G13027];
[GL:G13026];
[GL:G00015];
[GL:G10818];
[GL:G13030];
[GL:G00031];
4,4'-Diaponeurosporenic acid [CPD:C16146];
Pelargonidin 3-O-glucoside [CPD:C12137];
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) [CPD:C16297];
Delphinidin 3-O-glucoside [CPD:C12138];
Cyanidin [CPD:C05905];
Cyanidin 5-O-glucoside [CPD:C16298];
Delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside
[CPD:C16304];
Cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) [CPD:C12643];
UDP-glucuronate [CPD:C00167];
Naringenin chalcone [CPD:C06561];
Zeatin [CPD:C00371];
Dihydrozeatin [CPD:C02029];
Curcumin [CPD:C10443];
Curcumin monoglucoside [CPD:C17749];
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole [CPD:C05604];
cyclo-Dopa 5-O-glucoside [CPD:C17751];
Betanidin [CPD:C08539];
Betanin [CPD:C08540];
alpha-L-Rhamnosyl-(1->3)-alpha-D-galactosyl-diphosphoundecaprenol
[CPD:C17959];
UDP-N-acetyl-D-glucosamine [CPD:C00043];
2-Deoxystreptamine [CPD:C02627]
Product Galactan [CPD:C05796];
UDP [CPD:C00015];
GDP [CPD:C00035];
Mannan [CPD:C00464];
1,4-beta-D-Mannan [CPD:C02492];
beta-D-Galactosyl-1,4-beta-D-glucosylceramide [CPD:C01290];
Digalactosylceramide [CPD:C06126];
alpha-D-Mannosylchitobiosyldiphosphodolichol [CPD:C04615];
Diglucosyl-diacylglycerol [CPD:C06040];
Salidroside [CPD:C06046];
Erythronolide B [CPD:C06635];
dTDP-L-mycarose [CPD:C11916];
Erythromycin D [CPD:C06633];
dTDP [CPD:C00363];
UDP [GL:G10619];
[GL:G00102];
[GL:G00103];
Dolichyl phosphate [GL:G10622];
[GL:G00148];
Paragloboside [GL:G00050];
iso-nLc8Cer [GL:G00078];
GDP [GL:G10620];
Type II B antigen [GL:G00052];
nLc6Cer [GL:G00067];
nLc8Cer [GL:G00069];
[GL:G00073];
[GL:G00057];
[GL:G10532];
V3Fuc,III3Fuc-nLc6Cer [GL:G00090];
[GL:G00085];
[GL:G00086];
[GL:G00082];
III3Fuc-nLc6Cer [GL:G00076];
Ga2-Cer [GL:G00497];
[GL:G00005];
[GL:G10598];
[GL:G10599];
[GL:G00008];
Lactosylceramide [GL:G00092];
Demethylmacrocin [CPD:C02400];
Cyanin [CPD:C08639];
Cyanidin 3-O-(6-O-p-coumaroyl)glucoside-5-O-glucoside [CPD:C12096];
Urdamycin B [CPD:C12406];
Urdamycin A [CPD:C12413];
Jadomycin B [CPD:C12395];
Premithramycin A1 [CPD:C12384];
Cyanidin 3-O-rutinoside [CPD:C08620];
Zeaxanthin diglucoside [CPD:C15969];
Sda antigen [GL:G00736];
[GL:G13023];
[GL:G13024];
[GL:G13025];
[GL:G11136];
[GL:G13026];
[GL:G13028];
[GL:G10818];
[GL:G13030];
[GL:G13029];
[GL:G00032];
Glycosyl-4,4'-diaponeurosporenoate [CPD:C16147];
Pelargonin [CPD:C08725];
Pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside
[CPD:C12640];
Pelargonidin 3-O-sophoroside [CPD:C16305];
Cyanidin 3-O-sophoroside [CPD:C16306];
Delphinidin 3-O-sophoroside [CPD:C16307];
Tulipanin [CPD:C16315];
Cyanidin 5-O-glucoside [CPD:C16298];
Delphin [CPD:C16312];
Ternatin C5 [CPD:C16303];
Cyanidin-3-O-(6''-O-malonyl-2''-O-glucuronyl)glucoside [CPD:C16373];
Phlorizin chalcone [CPD:C16406];
trans-Zeatin-7-beta-D-glucoside [CPD:C16443];
Dihydrozeatin-O-glucoside [CPD:C16448];
Curcumin monoglucoside [CPD:C17749];
Curcumin diglucoside [CPD:C17750];
cyclo-Dopa 5-O-glucoside [CPD:C17751];
cyclo-Dopa-glucuronylglucoside [CPD:C17752];
Betanin [CPD:C08540];
Amaranthin [CPD:C08537];
Gomphrenin-I [CPD:C08544];
D-Mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid [CPD:C04724];
2'-N-Acetylparomamine [CPD:C17582]
KEGG   ENZYME: 2.4.1.122Help
Entry
EC 2.4.1.122                Enzyme                                 
Name glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase;
uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname UDP-galactose:glycoprotein-N-acetyl-D-galactosamine
3-beta-D-galactosyltransferase
Reaction(IUBMB) UDP-galactose + glycoprotein N-acetyl-D-galactosamine = UDP +
glycoprotein D-galactosyl-(1->3)-N-acetyl-D-galactosamine
[RN:R05908]
Reaction(KEGG) R05908(G)
Show
Substrate UDP-galactose [CPD:C00052];
glycoprotein N-acetyl-D-galactosamine
Product UDP [CPD:C00015];
glycoprotein D-galactosyl-(1->3)-N-acetyl-D-galactosamine
Comment The non-reducing O-serine-linked N-acetylgalactosamine residues in
mucin glycoproteins can act as acceptors.
Pathway PATH: ec00512  O-Glycan biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K00731  glycoprotein-N-acetylgalactosamine
            3-beta-galactosyltransferase
Genes HSA: 56913(C1GALT1)
PTR: 472288(C1GALT1)
MCC: 696870
MMU: 94192(C1galt1)
RNO: 65044(C1galt1)
CFA: 482314(C1GALT1)
BTA: 539417(C1GALT1)
ECB: 100063865
GGA: 420575(C1GALT1)
TGU: 100221974
XLA: 444326
DRE: 337131(c1galt1b) 557675(c1galt1a)
DME: Dmel_CG9520
NVE: NEMVE_v1g89529
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:6789880]
Hesford FJ, Berger EG, Van den Eijnden DH.
Identification of the product formed by human erythrocyte
galactosyltransferase.
Biochim. Biophys. Acta. 659 (1981) 302-11.
Homo sapiens [GN:hsa]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:6801057]
Mendicino J, Sivakami S, Davila M, Chandrasekaran EV.
Purification and properties of UDP-gal:N-acetylgalactosaminide
mucin: beta 1,3-galactosyltransferase from swine trachea mucosa.
J. Biol. Chem. 257 (1982) 3987-94.
Sus scofa [GN:ssc]
Reference
  Authors
  Title

  Journal
 3  [PMID:6366476]
Schachter H, Narasimhan S, Gleeson P, Vella G.
Glycosyltransferases involved in elongation of N-glycosidically
linked oligosaccharides of the complex or N-acetyllactosamine type.
Methods. Enzymol. 98 (1983) 98-134.
Other DBs ExplorEnz - The Enzyme Database: 2.4.1.122
IUBMB Enzyme Nomenclature: 2.4.1.122
ExPASy - ENZYME nomenclature database: 2.4.1.122
BRENDA, the Enzyme Database: 2.4.1.122
CAS: 97089-61-7
DBGET integrated database retrieval system