KEGG   ENZYME: 2.4.1.119Help
Entry
EC 2.4.1.119                Enzyme                                 
Name dolichyl-diphosphooligosaccharide---protein glycotransferase;
dolichyldiphosphooligosaccharide-protein glycosyltransferase;
asparagine N-glycosyltransferase;
dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase;
dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase;
oligomannosyltransferase;
oligosaccharide transferase;
dolichyldiphosphoryloligosaccharide-protein
oligosaccharyltransferase
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname dolichyl-diphosphooligosaccharide:protein-L-asparagine
oligopolysaccharidotransferase
Reaction(IUBMB) dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl
diphosphate + a glycoprotein with the oligosaccharide chain attached
by N-glycosyl linkage to protein L-asparagine [RN:R04216]
Reaction(KEGG) R04216 > R05976(G)
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Substrate dolichyl diphosphooligosaccharide [CPD:C04213];
protein L-asparagine [CPD:C03021]
Product dolichyl diphosphate [CPD:C00621];
glycoprotein with the oligosaccharide chain attached by N-glycosyl
linkage to protein L-asparagine [CPD:C11572]
Comment Transfers the glucosyl-mannosyl-glucosamine polysaccharide
side-chains of glycoproteins to an asparagine residue in the
sequence Asn-Xaa-Ser or Asn-Xaa-Thr in the nascent polypeptide
chains of the protein moiety.
Pathway PATH: ec00510  N-Glycan biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K07151  dolichyl-diphosphooligosaccharide--protein
            glycosyltransferase
Genes HSA: 201595(STT3B) 3703(STT3A)
PTR: 451648(STT3A) 746396(STT3B)
MCC: 703434 717056
MMU: 16430(Stt3a) 68292(Stt3b)
RNO: 500972(Stt3a)
CFA: 485628(STT3B) 489300(STT3A)
BTA: 504474(STT3B) 507815(STT3A)
ECB: 100072333
MDO: 100016135
OAA: 100077452 100090390
GGA: 428444(RCJMB04_8n14)
TGU: 100225468 100230089
XLA: 399234(itm1)
XTR: 407861
DRE: 266797(itm1)
BFO: BRAFLDRAFT_101929 BRAFLDRAFT_69762
CIN: 100177361 100182725
SPU: 581211 752085 759320
DME: Dmel_CG1518 Dmel_CG7748(OstStt3)
DPO: Dpse_GA22298 Dpse_GA22539
DAN: Dana_GF17105 Dana_GF21857
DER: Dere_GG12291 Dere_GG17558
DPE: Dper_GL16584 Dper_GL21896
DSE: Dsec_GM17756 Dsec_GM22642
DSI: Dsim_GD18237 Dsim_GD24643
DYA: Dyak_GE10744 Dyak_GE15319
DGR: Dgri_GH12900 Dgri_GH19585
DMO: Dmoj_GI14454 Dmoj_GI23816
AGA: AgaP_AGAP000434 AgaP_AGAP002396
AAG: AaeL_AAEL002804 AaeL_AAEL004228
CQU: CpipJ_CPIJ008679 CpipJ_CPIJ015587
AME: 409265
NVI: 100117025 100117843
TCA: 661059
API: 100163072 100168884
ISC: IscW_ISCW022325
CEL: T12A2.2
CBR: CBG17485
BMY: Bm1_06940 Bm1_32435
SMM: Smp_075860.2 Smp_158600
NVE: NEMVE_v1g180767 NEMVE_v1g238356
HMG: 100202029 100205648
TAD: TRIADDRAFT_31147 TRIADDRAFT_36216
ATH: AT1G34130(STT3B) AT5G19690(STT3A)
POP: POPTR_1094997 POPTR_578521 POPTR_743464
RCU: RCOM_1050370 RCOM_1669180
VVI: 100232931(LTM1) 100261650
OSA: 4337389(Os04g0675500) 4339345(Os05g0519900)
SBI: SORBI_03g034385(SORBIDRAFT_03g034385)
     SORBI_06g032800(SORBIDRAFT_06g032800)
     SORBI_09g025920(SORBIDRAFT_09g025920)
ZMA: 100192699 100279881
PPP: PHYPADRAFT_186785 PHYPADRAFT_200115
CRE: CHLREDRAFT_127991(GTR25)
OLU: OSTLU_49512
CME: CMO226C
SCE: YGL022W(STT3)
AGO: AGOS_AFR491W
KLA: KLLA0C11627g
LTH: KLTH0E07502g
DHA: DEHA0B04455g
PIC: PICST_82607(STT3)
PPA: PAS_chr1-4_0685
VPO: Kpol_1025p46
LEL: LELG_00928
ZRO: ZYRO0G09878g
CAL: CaO19.1478(STT3) CaO19.9053(STT3)
CTP: CTRG_01261
CDU: CD36_16530
CGR: CAGL0A00209g
YLI: YALI0B16434g
SPO: SPBC1271.02(stt3)
NCR: NCU10497
PAN: PODANSg2068
MGR: MGG_04773
FGR: FG00430.1
ANI: AN1455.2
AFM: AFUA_8G04430
AOR: AO090103000069
ANG: An16g08570
AFV: AFLA_011600
PCS: Pc21g05240
NFI: NFIA_097170
CIM: CIMG_02206
URE: UREG_01512
SSL: SS1G_01854
BFU: BC1G_02512
CNE: CNI01850
CNB: CNBH1740
LBC: LACBIDRAFT_305018(STT3)
UMA: UM05293.1
MGL: MGL_3807
MBR: MONBRDRAFT_8324
DDI: DDB_0230191(stt3)
EHI: EHI_011940 EHI_118880
EDI: EDI_227620 EDI_332460
PFA: PF11_0173
PFD: PFDG_02901
PFH: PFHG_04037
PYO: PY02151
PCB: PC000448.00.0 PC000621.03.0
PBE: PB000857.03.0
PKN: PKH_091400
PVX: PVX_091460
BBO: BBOV_II000220
CPV: cgd6_2040
CHO: Chro.60239
TGO: TGME49_031430
TET: TTHERM_00877020
PTM: GSPATT00008559001
TBR: Tb927.5.890 Tb927.5.900 Tb927.5.910
TCR: 505163.80
LMA: LmjF35.1130 LmjF35.1140 LmjF35.1150 LmjF35.1160
LIF: LinJ35.1220 LinJ35.1230 LinJ35.1240
LBZ: LbrM27_V2.0430 LbrM34_V2.1050 LbrM34_V2.1060 LbrM34_V2.1070
GLA: GL50803_137685
TVA: TVAG_077860 TVAG_131010 TVAG_230650 TVAG_430200
PTI: PHATRDRAFT_55197 PHATRDRAFT_55198
TPS: THAPSDRAFT_261710(STT3b) THAPSDRAFT_4160
WSU: WS0043(wlaF)
TDN: Suden_1474
CJE: Cj1126c(pglB)
CJR: CJE1268(pglB)
CJJ: CJJ81176_1143(pglB)
CJU: C8J_1066(wlaF)
CJD: JJD26997_0595(pglB)
CFF: CFF8240_1383
CCV: CCV52592_1213 CCV52592_1220
CHA: CHAB381_0954
CCO: CCC13826_0452(fecD) CCC13826_0460
CLA: Cla_1253(pglB)
SDL: Sdel_1767
NIS: NIS_1250
SUN: SUN_0103
NAM: NAMH_1652
GEO: Geob_1424 Geob_2990
DVU: DVU1252
DVL: Dvul_1810
DVM: DvMF_0846
DDE: Dde_3699
DDS: Ddes_0746
DSA: Desal_3646
DBA: Dbac_3265
DRT: Dret_0285
MJA: MJ1525
MFE: Mefer_0590
MVU: Metvu_0243
MMP: MMP1424
MMQ: MmarC5_0154
MMX: MmarC6_1249
MMZ: MmarC7_0669
MAE: Maeo_1409
MVN: Mevan_0735
MAC: MA1172 MA3752 MA3753 MA3754
MBA: Mbar_A0242 Mbar_A0243 Mbar_A0368
MMA: MM_0646 MM_0647 MM_2210
MBU: Mbur_1579
MTP: Mthe_1164 Mthe_1498 Mthe_1548
MHU: Mhun_2270 Mhun_2859 Mhun_3066 Mhun_3149
MLA: Mlab_0662
MEM: Memar_0175 Memar_2235
MBN: Mboo_0249 Mboo_1209
MPL: Mpal_0785
MPD: MCP_2705 MCP_2723
MTH: MTH1623 MTH1898 MTH1906 MTH420
MST: Msp_0368
MSI: Msm_0716
AFU: AF0040 AF0329 AF0380
HAL: VNG0005H VNG1068G(tot)
HSL: OE1008F OE2548F(stt3)
HMA: rrnAC0431(tot) rrnAC3242
HWA: HQ2681A(stt3) HQ2945A(stt3)
NPH: NP3720A(stt3)
HLA: Hlac_1062
HUT: Huta_2131 Huta_2808
HMU: Hmuk_1479 Hmuk_2752
TAC: Ta1136
TVO: TVN1212
PTO: PTO0785 PTO0786
PHO: PH0242 PH1271
PAB: PAB0974 PAB1586 PAB2202
PFU: PF0156 PF0411
TKO: TK0810 TK1718
TON: TON_0775 TON_1820
TGA: TGAM_0406 TGAM_0937
TSI: TSIB_0007 TSIB_0418
RCI: LRC539 LRC541 LRC558
SMR: Smar_0223
IHO: Igni_0016
DKA: DKAM_0136
HBU: Hbut_1205
SSO: SSO1052
STO: ST0940
SAI: Saci_1274
SIS: LS215_1264
SIA: M1425_1167
SIM: M1627_1231
SID: M164_1156
SIY: YG5714_1163
SIN: YN1551_1688
MSE: Msed_1805
PAI: PAE3030
PIS: Pisl_0431
PCL: Pcal_0997
PAS: Pars_1781
CMA: Cmaq_0438
TNE: Tneu_1689
TPE: Tpen_0640
NMR: Nmar_0075
NEQ: NEQ155
KCR: Kcr_1056
Taxonomy
Structures PDB: 1RKL  3G7Y  3G9B  3GA4  
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:6933437]
Das RC, Heath EC.
Dolichyldiphosphoryloligosaccharide--protein
oligosaccharyltransferase; solubilization, purification, and
properties.
Proc. Natl. Acad. Sci. U. S. A. 77 (1980) 3811-5.
Bos taurus [GN:bta]
Other DBs ExplorEnz - The Enzyme Database: 2.4.1.119
IUBMB Enzyme Nomenclature: 2.4.1.119
ExPASy - ENZYME nomenclature database: 2.4.1.119
BRENDA, the Enzyme Database: 2.4.1.119
CAS: 75302-32-8
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