| Entry |
|
|---|
| Name |
glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase;
uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
 |
|---|
| Sysname |
UDP-galactose:glycoprotein-N-acetyl-D-galactosamine
3-beta-D-galactosyltransferase |
|---|
| Reaction(IUBMB) |
UDP-galactose + glycoprotein N-acetyl-D-galactosamine = UDP +
glycoprotein D-galactosyl-(1->3)-N-acetyl-D-galactosamine
[RN:R05908] |
|---|
| Reaction(KEGG) |
R05908(G)
 |
|---|
| Substrate |
UDP-galactose [CPD:C00052];
glycoprotein N-acetyl-D-galactosamine |
|---|
| Product |
UDP [CPD:C00015];
glycoprotein D-galactosyl-(1->3)-N-acetyl-D-galactosamine |
|---|
| Comment |
The non-reducing O-serine-linked N-acetylgalactosamine residues in
mucin glycoproteins can act as acceptors. |
|---|
| Pathway |
PATH: ec00512 O-Glycan biosynthesis
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00731 glycoprotein-N-acetylgalactosamine
3-beta-galactosyltransferase |
|---|
| Genes |
HSA: 56913(C1GALT1)
PTR: 472288(C1GALT1)
MCC: 696870
MMU: 94192(C1galt1)
RNO: 65044(C1galt1)
CFA: 482314(C1GALT1)
BTA: 539417(C1GALT1)
ECB: 100063865
GGA: 420575(C1GALT1)
TGU: 100221974
XLA: 444326
DRE: 337131(c1galt1b) 557675(c1galt1a)
DME: Dmel_CG9520
NVE: NEMVE_v1g89529
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6789880]
Hesford FJ, Berger EG, Van den Eijnden DH.
Identification of the product formed by human erythrocyte
galactosyltransferase.
Biochim. Biophys. Acta. 659 (1981) 302-11.
Homo sapiens [GN:hsa] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6801057]
Mendicino J, Sivakami S, Davila M, Chandrasekaran EV.
Purification and properties of UDP-gal:N-acetylgalactosaminide
mucin: beta 1,3-galactosyltransferase from swine trachea mucosa.
J. Biol. Chem. 257 (1982) 3987-94.
Sus scofa [GN:ssc] |
|---|
Reference
Authors
Title
Journal
|
3 [PMID:6366476]
Schachter H, Narasimhan S, Gleeson P, Vella G.
Glycosyltransferases involved in elongation of N-glycosidically
linked oligosaccharides of the complex or N-acetyllactosamine type.
Methods. Enzymol. 98 (1983) 98-134. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.1.122
IUBMB Enzyme Nomenclature: 2.4.1.122
ExPASy - ENZYME nomenclature database: 2.4.1.122
BRENDA, the Enzyme Database: 2.4.1.122
CAS: 97089-61-7 |
|---|
