KEGG   ENZYME: 2.4.1.13Help
Entry
EC 2.4.1.13                 Enzyme                                 

Name
sucrose synthase;
UDPglucose-fructose glucosyltransferase;
sucrose synthetase;
sucrose-UDP glucosyltransferase;
sucrose-uridine diphosphate glucosyltransferase;
uridine diphosphoglucose-fructose glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Reaction(IUBMB)
NDP-glucose + D-fructose = NDP + sucrose [RN:R07256]
Reaction(KEGG)
Substrate
NDP-glucose [CPD:C15541];
D-fructose [CPD:C00095]
Product
NDP [CPD:C00454];
sucrose [CPD:C00089]
Comment
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].
History
EC 2.4.1.13 created 1961, modified 2003
Pathway
Starch and sucrose metabolism
Metabolic pathways
Orthology
K00695  
sucrose synthase
Genes
ATH: 
AT1G73370(SUS6) AT3G43190(SUS4) AT4G02280(SUS3) AT5G20830(SUS1) AT5G37180(SUS5) AT5G49190(SUS2)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os02t0831500-01(Os02g0831500) Os03t0340500-01(Os03g0340500) Os03t0401300-01(Os03g0401300) Os04t0249500-00(Os04g0249500) Os04t0309600-01(Os04g0309600) Os06t0194900-01(Os06g0194900) Os07t0616800-01(Os07g0616800)
OBR: 
BDI: 
SBI: 
SORBI_01g033060(SORBIDRAFT_01g033060) SORBI_01g035890(SORBIDRAFT_01g035890) SORBI_04g038410(SORBIDRAFT_04g038410)
ZMA: 
101027181 542091(sus2) 542247(sus1) 542365(SH-1)
SITA: 
ATR: 
s00044p00046900(AMTR_s00044p00046900) s00106p00019920(AMTR_s00106p00019920)
SMO: 
PPP: 
CSL: 
CVR: 
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NHL: 
NWA: 
HHC: 
TGR: 
AFE: 
AFR: 
ACU: 
AFI: 
NEU: 
NE1214(ss2)
NET: 
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DAK: 
TEL: 
THN: 
CYC: 
CYN: 
AMR: 
DSL: 
HAO: 
GLP: 
GEI: 
OAC: 
ONI: 
PSEU: 
CEP: 
MIC: 
ARP: 
GVI: 
gvip490(spsA)
GLJ: 
ANA: 
NPU: 
NOS: 
NOP: 
AVA: 
ANB: 
ACY: 
NAZ: 
CSG: 
CALO: 
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PLP: 
SCS: 
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DIN: 
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 » show all
Taxonomy
Reference
1
  Authors
Avigad, G. and Milner, Y.
  Title
UDP-glucose:fructose transglucosylase from sugar beet roots.
  Journal
Methods Enzymol. 8 (1966) 341-345.
Reference
2  [PMID:14367373]
  Authors
CARDINI CE, LELOIR LF, CHIRIBOGA J.
  Title
The biosynthesis of sucrose.
  Journal
J. Biol. Chem. 214 (1955) 149-55.
  Organism
Pseudomonas saccharophila
Reference
3  [PMID:4624446]
  Authors
Delmer DP.
  Title
The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings.
  Journal
J. Biol. Chem. 247 (1972) 3822-8.
  Organism
Phaseolus aureus
Reference
4  [PMID:5941994]
  Authors
Murata T, Sugiyama T, Minamikawa T, Akazawa T.
  Title
Enzymic mechanism of starch synthesis in ripening rice grains. 3. Mechanism of the sucrose-starch conversion.
  Journal
Arch. Biochem. Biophys. 113 (1966) 34-44.
  Organism
Oryza sativa
Reference
5  [PMID:10050318]
  Authors
Nakai T, Konishi T, Zhang XQ, Chollet R, Tonouchi N, Tsuchida T, Yoshinaga F, Mori H, Sakai F, Hayashi T.
  Title
An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11.
  Journal
Plant. Cell. Physiol. 39 (1998) 1337-41.
  Organism
Vigna radiata
Reference
6  [PMID:10592030]
  Authors
Porchia AC, Curatti L, Salerno GL.
  Title
Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence.
  Journal
Planta. 210 (1999) 34-40.
  Organism
Anabaena sp.
Reference
7  [PMID:16653008]
  Authors
Ross HA, Davies HV.
  Title
Purification and Characterization of Sucrose Synthase from the Cotyledons of Vicia faba L.
  Journal
Plant. Physiol. 100 (1992) 1008-1013.
  Organism
Vicia fava
Reference
8  [PMID:16661094]
  Authors
Silvius JE, Snyder FW.
  Title
Comparative Enzymic Studies of Sucrose Metabolism in the Taproots and Fibrous Roots of Beta vulgaris L.
  Journal
Plant. Physiol. 64 (1979) 1070-1073.
  Organism
Beta vulgaris
Reference
9  [PMID:10845453]
  Authors
Tanase K, Yamaki S.
  Title
Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit.
  Journal
Plant. Cell. Physiol. 41 (2000) 408-14.
  Organism
Pyrus serotina
Reference
10 [PMID:12773636]
  Authors
Baroja-Fernandez E, Munoz FJ, Saikusa T, Rodriguez-Lopez M, Akazawa T, Pozueta-Romero J.
  Title
Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants.
  Journal
Plant. Cell. Physiol. 44 (2003) 500-9.
  Organism
Hordeum vulgare
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9030-05-1

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