KEGG   ENZYME: 2.4.1.130Help
Entry
EC 2.4.1.130                Enzyme                                 
Name dolichyl-phosphate-mannose---glycolipid alpha-mannosyltransferase;
dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase;
oligomannosylsynthase
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase
Reaction(IUBMB) Transfers an alpha-D-mannosyl residue from dolichyl-phosphate
D-mannose into membrane lipid-linked oligosaccharide [RN:R06258
R06259 R06260 R06261]
Reaction(KEGG) R06258(G) R06259(G) R06260(G) R06261(G)
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Comment Four of the nine mannosyl residues in the main membrane lipid-linked
oligosaccharide of the structure Glc3Man9GlcNAc2 are produced by the
action of this enzyme.
Pathway PATH: ec00510  N-Glycan biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K03845  alpha-1,3-mannosyltransferase
KO: K03847  alpha-1,6-mannosyltransferase
Genes HSA: 10195(ALG3) 79087(ALG12)
PTR: 460886(ALG3) 470247(ALG12)
MMU: 208624(Alg3) 223774(Alg12)
RNO: 287983(Alg3) 315212(Alg12)
CFA: 478653(ALG3) 481196(ALG12)
BTA: 100125314(ALG12) 614624(ALG3)
ECB: 100054702 100059007 100146652
OAA: 100073873
GGA: 417733(RCJMB04_1n22) 424952(ALG3) 769008(ALG12)
TGU: 100228059 100230731
XLA: 100037243(alg3)
XTR: 100127746 548874(alg12)
DRE: 553725(alg3) 569494(alg12)
BFO: BRAFLDRAFT_214627 BRAFLDRAFT_72229
CIN: 100176327 100177471
SPU: 576672
DME: Dmel_CG4084(l(2)not) Dmel_CG8412
DPO: Dpse_GA17945 Dpse_GA21058
DAN: Dana_GF11826 Dana_GF23035
DER: Dere_GG17092 Dere_GG20006
DPE: Dper_GL17591 Dper_GL24301
DSE: Dsec_GM15518 Dsec_GM23833
DSI: Dsim_GD18643 Dsim_GD25022
DYA: Dyak_GE11542 Dyak_GE25981
DGR: Dgri_GH17417 Dgri_GH20578
DMO: Dmoj_GI19772 Dmoj_GI22746
AGA: AgaP_AGAP000102 AgaP_AGAP007168
AAG: AaeL_AAEL002483 AaeL_AAEL013078 AaeL_AAEL014279
CQU: CpipJ_CPIJ009375 CpipJ_CPIJ010838
AME: 724399 724431 727115
NVI: 100115752 100120808
TCA: 655451 660266
API: 100159224 100160697
ISC: IscW_ISCW010680 IscW_ISCW012893
CEL: K09E4.2 ZC513.5
CBR: CBG11382 CBG20997
BMY: Bm1_50775
SMM: Smp_150200 Smp_161590
NVE: NEMVE_v1g159238 NEMVE_v1g32894
HMG: 100214068 100214877
TAD: TRIADDRAFT_28195
ATH: AT1G02145 AT2G47760(ALG3)
POP: POPTR_731888 POPTR_816529
RCU: RCOM_0658290 RCOM_1439850
VVI: 100253051 100253790(GSVIVT00027968001)
OSA: 4327643(Os01g0172000) 4336560(Os04g0544900)
SBI: SORBI_03g004440(SORBIDRAFT_03g004440)
     SORBI_06g024210(SORBIDRAFT_06g024210)
ZMA: 100276684 100282442
PPP: PHYPADRAFT_13871 PHYPADRAFT_206317
OLU: OSTLU_43663 OSTLU_47741
CME: CMK113C
SCE: YBL082C(ALG3) YNR030W(ALG12)
AGO: AGOS_AAR043C AGOS_AGL299C
KLA: KLLA0C08591g KLLA0E20823g
LTH: KLTH0A06710g KLTH0C06314g
DHA: DEHA0A05984g DEHA0C18546g
PIC: PICST_31100(ECM39) PICST_58095(RHK1)
PPA: PAS_chr4_0544 PAS_chr4_0712
VPO: Kpol_1028p42 Kpol_1045p31
LEL: LELG_04879 LELG_05213
ZRO: ZYRO0B03696g ZYRO0D08250g
CAL: CaO19.1092(RHK1)
CTP: CTRG_02752 CTRG_05215
CDU: CD36_64690 CD36_72630
CGR: CAGL0A04587g CAGL0M10769g
YLI: YALI0C02475g YALI0E03190g
SPO: SPAC7D4.06c(alg3) SPBC1734.12c(alg12)
NCR: NCU06552 NCU07472
PAN: PODANSg09956
FGR: FG01233.1 FG09653.1
ANI: AN0104.2 AN3588.2
AFM: AFUA_4G12900 AFUA_5G11990
AOR: AO090009000318 AO090120000319
ANG: An01g08460 An18g02360
AFV: AFLA_051500
PCS: Pc21g07120 Pc22g02840
NFI: NFIA_075290 NFIA_103440
CIM: CIMG_00617 CIMG_09210
URE: UREG_00622
SSL: SS1G_10012 SS1G_14030
BFU: BC1G_07234 BC1G_07473
CNE: CNC03430 CNL04800
CNB: CNBC3790 CNBI2040
LBC: LACBIDRAFT_247511(ALG3) LACBIDRAFT_302539(ALG12)
MPR: MPER_04378 MPER_09769
MGL: MGL_2261
MBR: MONBRDRAFT_31470 MONBRDRAFT_38469
DDI: DDB_0231368(alg3) DDB_0231450(alg12)
TBR: Tb10.70.0260 Tb927.2.4720
TCR: 509317.50 510187.404 511621.60
LMA: LmjF36.2040
LIF: LinJ36.4580
LBZ: LbrM35_V2.2270
PTI: PHATRDRAFT_10976 PHATRDRAFT_44425
TPS: THAPSDRAFT_262459 THAPSDRAFT_34773
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:6163773]
Rearick JI, Fujimoto K, Kornfeld S.
Identification of the mannosyl donors involved in the synthesis of
lipid-linked oligosaccharides.
J. Biol. Chem. 256 (1981) 3762-9.
Mus musculus [GN:mmu]
Other DBs ExplorEnz - The Enzyme Database: 2.4.1.130
IUBMB Enzyme Nomenclature: 2.4.1.130
ExPASy - ENZYME nomenclature database: 2.4.1.130
BRENDA, the Enzyme Database: 2.4.1.130
CAS: 77967-76-1
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