| Entry |
|
|---|
| Name |
N-acetylglucosaminyldiphosphodolichol
N-acetylglucosaminyltransferase;
UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase;
uridine diphosphoacetylglucosamine-dolichylacetylglucosamine
pyrophosphate acetylglucosaminyltransferase;
N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
 |
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| Sysname |
UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol
N-acetyl-D-glucosaminyltransferase |
|---|
| Reaction(IUBMB) |
UDP-N-acetyl-D-glucosamine +
N-acetyl-D-glucosaminyl-diphosphodolichol = UDP +
N,N'-diacetylchitobiosyl-diphosphodolichol [RN:R04494 R05970] |
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| Reaction(KEGG) |
R04494 R05970(G)
 |
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| Substrate |
UDP-N-acetyl-D-glucosamine [CPD:C00043];
N-acetyl-D-glucosaminyl-diphosphodolichol [CPD:C04500] |
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| Product |
UDP [CPD:C00015];
N,N'-diacetylchitobiosyl-diphosphodolichol |
|---|
| Pathway |
PATH: ec00510 N-Glycan biosynthesis
PATH: ec01100 Metabolic pathways |
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| Orthology |
KO: K07432 beta-1,4-N-acetylglucosaminyltransferase
KO: K07441 beta-1,4-N-acetylglucosaminyltransferase |
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| Genes |
HSA: 199857(ALG14) 79868(ALG13)
MCC: 706863 709630
MMU: 320302(Glt28d2) 66789(Alg14) 67574(Alg13)
RNO: 300284(Alg13) 362031(Alg14)
CFA: 481021(ALG13) 612241(ALG14)
BTA: 506537(ALG14)
SSC: 100157203
ECB: 100058111
MDO: 100012443 100032901
OAA: 100076389
GGA: 422339(ALG13) 424484(ALG14)
TGU: 100227409
XLA: 431927
XTR: 549862
DRE: 436733 450072(alg14)
BFO: BRAFLDRAFT_115464
CIN: 100181785
SPU: 575376
DME: Dmel_CG14512 Dmel_CG6308
DPO: Dpse_GA13043 Dpse_GA19504
DAN: Dana_GF21906 Dana_GF22939
DER: Dere_GG12036 Dere_GG17884
DPE: Dper_GL13417 Dper_GL23604
DSE: Dsec_GM12261 Dsec_GM19574
DSI: Dsim_GD17960
DYA: Dyak_GE10474 Dyak_GE17190
DGR: Dgri_GH12321 Dgri_GH13947
DMO: Dmoj_GI21466 Dmoj_GI24839
AGA: AgaP_AGAP003461 AgaP_AGAP003699
AAG: AaeL_AAEL002805 AaeL_AAEL013240
CQU: CpipJ_CPIJ004014 CpipJ_CPIJ012472
AME: 726253 726726
NVI: 100115468 100119727
TCA: 660529 662245
API: 100167930
ISC: IscW_ISCW007482
CEL: M02B7.4 R10D12.12
CBR: CBG10740 CBG11418
BMY: Bm1_10570 Bm1_52490
SMM: Smp_045430.3 Smp_082710.3
NVE: NEMVE_v1g216472 NEMVE_v1g44380
HMG: 100210782
TAD: TRIADDRAFT_18956 TRIADDRAFT_22933
ATH: AT4G16710 AT4G18230
POP: POPTR_570876 POPTR_782868 POPTR_815480
RCU: RCOM_1358640 RCOM_1430860
VVI: 100262464(GSVIVT00003408001) 100267547
OSA: 4329330(Os02g0467700) 4333143(Os03g0423200)
SBI: SORBI_08g001790(SORBIDRAFT_08g001790)
SORBI_08g004690(SORBIDRAFT_08g004690)
SORBI_08g016480(SORBIDRAFT_08g016480)
ZMA: 100217271 100280032 100285424(AY110060)
PPP: PHYPADRAFT_142865 PHYPADRAFT_145686
CRE: CHLREDRAFT_177895 CHLREDRAFT_182754
OLU: OSTLU_43197 OSTLU_43228 OSTLU_8530
CME: CME091C CMS225C
SCE: YBR070C(ALG14) YGL047W(ALG13)
AGO: AGOS_AGL042W AGOS_AGL202W
KLA: KLLA0A04774g KLLA0F18865g
LTH: KLTH0C05082g KLTH0D03828g
DHA: DEHA0D07128g DEHA0F07172g
PIC: PICST_32391 PICST_61591(ALG13)
PPA: PAS_chr1-4_0448 PAS_chr3_0944
VPO: Kpol_1026p24 Kpol_1052p11
LEL: LELG_01365 LELG_02336
ZRO: ZYRO0G12430g ZYRO0G22352g
CAL: CaO19.13446 CaO19.5363
CTP: CTRG_02038 CTRG_04377
CDU: CD36_00760 CD36_24570
CGR: CAGL0D06270g CAGL0E04180g
YLI: YALI0B11440g YALI0E33275g
SPO: SPAC56E4.02c(alg13) SPAC5D6.06c
NCR: NCU03344
PAN: PODANSg6469 PODANSg934
MGR: MGG_03927 MGG_07272
FGR: FG01652.1 FG09957.1
ANI: AN5736.2
AFM: AFUA_4G13400 AFUA_6G06940
AOR: AO090009000234
ANG: An01g09110
AFV: AFLA_052270
NFI: NFIA_052590 NFIA_102950
CIM: CIMG_00551 CIMG_04033
URE: UREG_00575 UREG_01931
SSL: SS1G_03933 SS1G_10797
BFU: BC1G_03814 BC1G_04562
CNE: CNB01840 CNB05490
CNB: CNBB0300 CNBB3880
LBC: LACBIDRAFT_247298
MPR: MPER_09768
MGL: MGL_4144
MBR: MONBRDRAFT_13897 MONBRDRAFT_28936
DDI: DDB_0231975(ugt1)
EHI: EHI_049660
EDI: EDI_167510
PFA: MAL8P1.133 PFB0515w
PFD: PFDG_00892 PFDG_02193
PFH: PFHG_02642 PFHG_04882
PYO: PY04598
PCB: PC000472.04.0 PC302316.00.0
PBE: PB000624.03.0 PB001130.00.0
PKN: PKH_011200 PKH_040860
PVX: PVX_002950 PVX_088230
TPV: TP02_0515
BBO: BBOV_II005640 BBOV_IV004090
CPV: cgd7_4930
CHO: Chro.70549
TGO: TGME49_007070
PTM: GSPATT00013198001
TBR: Tb927.6.1960
TCR: 504071.90
LMA: LmjF30.0530
LIF: LinJ30.0860
LBZ: LbrM30_V2.0610
GLA: GL50803_102978
TVA: TVAG_038800
PTI: PHATRDRAFT_14444 PHATRDRAFT_9427
TPS: THAPSDRAFT_17966
 |
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| Structures |
PDB: 2JZC |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:6215245]
Sharma CB, Lehle L, Tanner W.
Solubilization and characterization of the initial enzymes of the
dolichol pathway from yeast.
Eur. J. Biochem. 126 (1982) 319-25.
Saccharomyces cerevisiae [GN:sce] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:192724]
Turco SJ, Heath EC.
Glucuronosyl-N-acetylglucosaminyl pyrophosphoryldolichol. Formation
in SV40-transformed human lung fibroblasts and biosynthesis in rat
lung microsomal preparations.
J. Biol. Chem. 252 (1977) 2918-28.
Homo sapiens [GN:hsa], Rattus norvegicus [GN:rno] |
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| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.1.141
IUBMB Enzyme Nomenclature: 2.4.1.141
ExPASy - ENZYME nomenclature database: 2.4.1.141
BRENDA, the Enzyme Database: 2.4.1.141
CAS: 75536-54-8 |
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