KEGG   ENZYME: 2.4.1.142Help
Entry
EC 2.4.1.142                Enzyme                                 
Name chitobiosyldiphosphodolichol beta-mannosyltransferase;
guanosine diphosphomannose-dolichol diphosphochitobiose
mannosyltransferase;
GDP-mannose-dolichol diphosphochitobiose mannosyltransferase
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase
Reaction(IUBMB) GDP-mannose + chitobiosyldiphosphodolichol = GDP +
beta-(1->4)-D-mannosylchitobiosyldiphosphodolichol [RN:R04502
R05972]
Reaction(KEGG) R04502 R05972(G)
Show
Substrate GDP-mannose [CPD:C00096];
chitobiosyldiphosphodolichol [CPD:C04537]
Product GDP [CPD:C00035];
beta-(1->4)-D-mannosylchitobiosyldiphosphodolichol
Pathway PATH: ec00510  N-Glycan biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K03842  beta-1,4-mannosyltransferase
Genes HSA: 56052(ALG1)
PTR: 453895(ALG1)
MCC: 710713
MMU: 208211(Alg1)
RNO: 360475(Alg1)
CFA: 490017(ALG1)
BTA: 507210(ALG1)
MDO: 100026716
OAA: 100084909
GGA: 416393(ALG1)
TGU: 100223607
XLA: 100037043
XTR: 594994
DRE: 334161(alg1)
CIN: 100177331
SPU: 587377
DME: Dmel_CG18012
DPO: Dpse_GA26165
DAN: Dana_GF18249
DER: Dere_GG16746
DPE: Dper_GL12024
DSE: Dsec_GM15332
DSI: Dsim_GD20206
DYA: Dyak_GE25241
DGR: Dgri_GH17347
DMO: Dmoj_GI23885
AGA: AgaP_AGAP003551
AAG: AaeL_AAEL000451
CQU: CpipJ_CPIJ007482
AME: 551379
NVI: 100116972
TCA: 664134
API: 100166741
CEL: T26A5.4(Beta-mannosyltransferase)
CBR: CBG19680
BMY: Bm1_57590
SMM: Smp_005010
NVE: NEMVE_v1g212177
HMG: 100207677
TAD: TRIADDRAFT_33634
ATH: AT1G16570
POP: POPTR_583054
RCU: RCOM_0104430
VVI: 100247296
OSA: 4331831(Os03g0180700)
SBI: SORBI_01g045200(SORBIDRAFT_01g045200)
ZMA: 100282626
PPP: PHYPADRAFT_50684
CRE: CHLREDRAFT_108570(GTR16)
OLU: OSTLU_18368
CME: CMR050C
SCE: YBR110W(ALG1)
AGO: AGOS_ADL338C
KLA: KLLA0B09405g
LTH: KLTH0F10604g
DHA: DEHA0D11462g
PIC: PICST_39314(ALG1)
PPA: PAS_chr2-1_0759
VPO: Kpol_1065p18
LEL: LELG_04510
ZRO: ZYRO0C16368g
CAL: CaO19.11888(ALG1) CaO19.4410(ALG1)
CTP: CTRG_03901
CDU: CD36_45550
CGR: CAGL0K12342g
YLI: YALI0E34133g
SPO: SPAC23C4.14(alg1)
NCR: NCU07261
MGR: MGG_10494
FGR: FG09631.1
ANI: AN5346.2
AFM: AFUA_6G14180
AOR: AO090103000403
ANG: An06g01100
AFV: AFLA_008330
PCS: Pc22g00440
NFI: NFIA_060060
CIM: CIMG_02876
URE: UREG_02969
SSL: SS1G_02996
BFU: BC1G_14238
CNE: CNA06670
CNB: CNBA6490
LBC: LACBIDRAFT_300879(ALG1)
UMA: UM04649.1
MGL: MGL_3730
MBR: MONBRDRAFT_29828
DDI: DDB_0191150(alg1)
EHI: EHI_028950
EDI: EDI_136480
CPV: cgd7_1810
CHO: Chro.70211
TGO: TGME49_030590
TET: TTHERM_00954200
PTM: GSPATT00028628001
TBR: Tb10.389.0250
TCR: 504215.20
LMA: LmjF18.0900
LIF: LinJ18.0900
LBZ: LbrM18_V2.0960
TVA: TVAG_061110
PTI: PHATRDRAFT_14002
TPS: THAPSDRAFT_14643
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:6215245]
Sharma CB, Lehle L, Tanner W.
Solubilization and characterization of the initial enzymes of the
dolichol pathway from yeast.
Eur. J. Biochem. 126 (1982) 319-25.
Saccharomyces cerevisiae [GN:sce]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:10704531]
Takahashi T, Honda R, Nishikawa Y.
Cloning of the human cDNA which can complement the defect of the
yeast mannosyltransferase I-deficient mutant alg 1.
Glycobiology. 10 (2000) 321-7.
Homo sapiens [GN:hsa]
Other DBs ExplorEnz - The Enzyme Database: 2.4.1.142
IUBMB Enzyme Nomenclature: 2.4.1.142
ExPASy - ENZYME nomenclature database: 2.4.1.142
BRENDA, the Enzyme Database: 2.4.1.142
CAS: 83380-85-2
DBGET integrated database retrieval system