| Entry |
|
|---|
| Name |
acetylgalactosaminyl-O-glycosyl-glycoprotein
beta-1,3-N-acetylglucosaminyltransferase;
O-glycosyl-oligosaccharide-glycoprotein
N-acetylglucosaminyltransferase III;
uridine diphosphoacetylglucosamine-mucin
beta(1->3)-acetylglucosaminyltransferase;
mucin core 3 beta3-GlcNAc-transferase;
Core 3beta-GlcNAc-transferase;
UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein
(N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R)
beta-1,3-N-acetyl-D-glucosaminyltransferase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
 |
|---|
| Sysname |
UDP-N-acetyl-D-glucosamine:N-acetyl-beta-D-galactosaminyl-R
3-beta-N-acetyl-D-glucosaminyltransferase |
|---|
| Reaction(IUBMB) |
UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-galactosaminyl-R = UDP
+
N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
[RN:R03513] |
|---|
| Reaction(KEGG) |
R03513;
(other) R05909(G)
 |
|---|
| Substrate |
UDP-N-acetyl-D-glucosamine [CPD:C00043];
N-acetyl-beta-D-galactosaminyl-R [CPD:C04135] |
|---|
| Product |
UDP [CPD:C00015];
N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R |
|---|
| Comment |
cf. EC 2.4.1.102 (beta-1,3-galactosyl-O-glycosyl-glycoprotein
beta-1,6-N-acetylglucosaminyltransferase), EC 2.4.1.146
(beta-1,3-galactosyl-O-glycosyl-glycoprotein
beta-1,3-N-acetylglucosaminyltransferase) and EC 2.4.1.148
(acetylgalactosaminyl-O-glycosyl-glycoprotein
beta-1,6-N-acetylglucosaminyltransferase). |
|---|
| Pathway |
PATH: ec00512 O-Glycan biosynthesis
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00739 acetylgalactosaminyl-0-glycosyl-glycoprotein
beta-1,3-N-acetylglucosaminyltransferase |
|---|
| Genes |
HSA: 192134(B3GNT6)
PTR: 451437(B3GNT1)
MCC: 697946
MMU: 272411(B3gnt6)
RNO: 292325(B3gnt6)
CFA: 485176(B3GNT1)
BTA: 540848(B3GNT6) 786615(B3GNT6)
ECB: 100146508
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6226356]
Brockhausen I, Rachaman ES, Matta KL, Schachter H.
The separation by liquid chromatography (under elevated pressure) of
phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides.
Analysis of substrates and products for four
N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis.
Carbohydr. Res. 120 (1983) 3-16.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.1.147
IUBMB Enzyme Nomenclature: 2.4.1.147
ExPASy - ENZYME nomenclature database: 2.4.1.147
BRENDA, the Enzyme Database: 2.4.1.147
CAS: 87927-96-6 |
|---|
