| Entry |
|
|---|
| Name |
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-acetyllactosaminide
beta1->3-acetylglucosaminyltransferase;
poly-N-acetyllactosamine extension enzyme;
Galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase;
UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase;
N-acetyllactosamine beta(1-3)N-acetylglucosaminyltransferase;
UDP-GlcNAc:Galbeta1->4GlcNAcbeta-Rbeta1->3-N-
acetylglucosaminyltransferase;
GnTE;
UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-
glucosamine beta-1,3-acetyl-D-glucosaminyltransferase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
 |
|---|
| Sysname |
UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->4)-N-acetyl-D-gluco
samine 3-beta-N-acetyl-D-glucosaminyltransferase |
|---|
| Reaction(IUBMB) |
UDP-N-acetyl-D-glucosamine +
beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP +
N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-
acetyl-D-glucosaminyl-R [RN:R02789] |
|---|
| Reaction(KEGG) |
R02789 > R05974(G) R05975(G);
(other) R04659
 |
|---|
| Substrate |
UDP-N-acetyl-D-glucosamine [CPD:C00043];
beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R [CPD:C00694] |
|---|
| Product |
UDP [CPD:C00015];
N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-
acetyl-D-glucosaminyl-R [CPD:C04890] |
|---|
| Comment |
Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on
asialo-alpha1-acid glycoprotein and other glycoproteins and
oligosaccharides. |
|---|
| Pathway |
PATH: ec00533 Keratan sulfate biosynthesis
PATH: ec00601 Glycosphingolipid biosynthesis - lacto and neolacto
series
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00741 N-acetyllactosaminide
beta-1,3-N-acetylglucosaminyltransferase |
|---|
| Genes |
HSA: 10678(B3GNT2) 11041(B3GNT1)
PTR: 451344(B3GNT1)
MCC: 693396(B3GNT7) 714270(B3GNT2)
MMU: 108902(B3gnt1) 53625(B3gnt2)
RNO: 293667(B3gnt1) 305571(B3gnt2)
CFA: 474611(B3GNT2) 476013(B3GNT1)
BTA: 515585(B3GNT2) 618055(B3GNT2)
ECB: 100058396 100064405
MDO: 100029667 100031891
OAA: 100078191 100086023
GGA: 421286(B3GNT2)
TGU: 100217506 100231337
XLA: 414647
XTR: 100170561
DRE: 564450 793362
SPU: 577047
DME: Dmel_CG11149 Dmel_CG15483 Dmel_CG3253
CEL: F22F7.6
NVE: NEMVE_v1g123568
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3160874]
Takeya A, Hosomi O, Kogure T.
The presence of N-acetyllactosamine and lactose: beta
(1-3)N-acetylglucosaminyltransferase activity in human urine.
Jpn. J. Med. Sci. Biol. 38 (1985) 1-8.
Homo sapiens [GN:hsa] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6219989]
van den Eijnden DH, Winterwerp H, Smeeman P, Schiphorst WE.
Novikoff ascites tumor cells contain N-acetyllactosaminide beta 1
leads to 3 and beta 1 leads to 6 N-acetylglucosaminyltransferase
activity.
J. Biol. Chem. 258 (1983) 3435-7.
Homo sapiens [GN:hsa] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.1.149
IUBMB Enzyme Nomenclature: 2.4.1.149
ExPASy - ENZYME nomenclature database: 2.4.1.149
BRENDA, the Enzyme Database: 2.4.1.149
CAS: 85638-39-7 |
|---|
