KEGG   ENZYME: 2.4.1.150Help
Entry
EC 2.4.1.150                Enzyme                                 

Name
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase;
N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase;
Galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase;
UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferasel UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminide 6-beta-N-acetyl-D-glucosaminyltransferase
Reaction(IUBMB)
UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R [RN:R02790]
Reaction(KEGG)
R02790;
(other) R06189(G)
Show
Substrate
UDP-N-acetyl-D-glucosamine [CPD:C00043];
beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R [CPD:C00694]
Product
UDP [CPD:C00015];
N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R [CPD:C04891]
Comment
Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo-alpha1-acid glycoprotein.
History
EC 2.4.1.150 created 1984
Pathway
Glycosphingolipid biosynthesis - lacto and neolacto series
Metabolic pathways
Orthology
K00742  
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase
Genes
HSA: 
2651(GCNT2)
PTR: 
PPS: 
GGO: 
PON: 
100173016(GCNT2)
MCC: 
697356 697468(GCNT2)
MCF: 
102131882(GCNT2)
MMU: 
14538(Gcnt2)
RNO: 
306860(Gcnt2)
CGE: 
HGL: 
TUP: 
CFA: 
488214 488215(GCNT2)
AML: 
FCA: 
BTA: 
BOM: 
PHD: 
CHX: 
100861326(GCNT2)
SSC: 
100152566(GCNT2)
CFR: 
ECB: 
MYB: 
MDO: 
SHR: 
OAA: 
GGA: 
420861(GCNT2) 428479
MGP: 
APLA: 
101795771(GCNT2)
FPG: 
101918293(GCNT2)
FCH: 
102057507(GCNT2)
CLV: 
102086182(GCNT2)
ASN: 
PSS: 
ACS: 
XLA: 
432275(gcnt2)
XTR: 
100038221(gcnt2)
LCM: 
102366551(GCNT2)
BFO: 
SPU: 
LOA: 
NVE: 
 » show all
Taxonomy
Reference
1  [PMID:6219989]
  Authors
van den Eijnden DH, Winterwerp H, Smeeman P, Schiphorst WE.
  Title
Novikoff ascites tumor cells contain N-acetyllactosaminide beta 1 leads to 3 and beta 1 leads to 6 N-acetylglucosaminyltransferase activity.
  Journal
J. Biol. Chem. 258 (1983) 3435-7.
  Organism
Homo sapiens [GN:hsa]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
85638-40-0

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