| Entry |
|
|---|
| Name |
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase;
N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-acetyllactosaminide
beta1->6-acetylglucosaminyltransferase;
Galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase;
UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferasel
UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-
glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
 |
|---|
| Sysname |
UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->4)-N-acetyl-D-gluco
saminide 6-beta-N-acetyl-D-glucosaminyltransferase |
|---|
| Reaction(IUBMB) |
UDP-N-acetyl-D-glucosamine +
beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP +
N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-
acetyl-D-glucosaminyl-R [RN:R02790] |
|---|
| Reaction(KEGG) |
R02790;
(other) R06189(G)
 |
|---|
| Substrate |
UDP-N-acetyl-D-glucosamine [CPD:C00043];
beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R [CPD:C00694] |
|---|
| Product |
UDP [CPD:C00015];
N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-
acetyl-D-glucosaminyl-R [CPD:C04891] |
|---|
| Comment |
Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on
asialo-alpha1-acid glycoprotein. |
|---|
| Pathway |
PATH: ec00601 Glycosphingolipid biosynthesis - lacto and neolacto
series
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00742 N-acetyllactosaminide
beta-1,6-N-acetylglucosaminyltransferase |
|---|
| Genes |
HSA: 2651(GCNT2)
PTR: 462428(GCNT2)
MCC: 697356 697468(GCNT2)
MMU: 14538(Gcnt2)
RNO: 306860(Gcnt2)
CFA: 488215(GCNT2)
BTA: 520336(GCNT2)
SSC: 100152566
ECB: 100063202 100063291
MDO: 100027080
OAA: 100084006 100084044
GGA: 420861(GCNT2)
XLA: 432275
SPU: 579029 760076
NVE: NEMVE_v1g110143
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6219989]
van den Eijnden DH, Winterwerp H, Smeeman P, Schiphorst WE.
Novikoff ascites tumor cells contain N-acetyllactosaminide beta 1
leads to 3 and beta 1 leads to 6 N-acetylglucosaminyltransferase
activity.
J. Biol. Chem. 258 (1983) 3435-7.
Homo sapiens [GN:hsa] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.1.150
IUBMB Enzyme Nomenclature: 2.4.1.150
ExPASy - ENZYME nomenclature database: 2.4.1.150
BRENDA, the Enzyme Database: 2.4.1.150
CAS: 85638-40-0 |
|---|
