| Entry |
|
|---|
| Name |
beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide
beta-1,3-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-acetyllactosaminide
beta1->3-acetylglucosaminyltransferase;
poly-N-acetyllactosamine extension enzyme;
UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-
glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
beta-1,3-acetylglucosaminyltransferase |
|---|
| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
 |
|---|
| Sysname |
UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-
glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)-ce
ramide 3-beta-N-acetylglucosaminyltransferase |
|---|
| Reaction(IUBMB) |
UDP-N-acetyl-D-glucosamine +
beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-
galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide = UDP +
N-acetyl-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-
beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-
(11)-ceramide [RN:R04659 R05975] |
|---|
| Reaction(KEGG) |
R04659 R05975(G);
(other) R04654 R06013(G)
 |
|---|
| Substrate |
UDP-N-acetyl-D-glucosamine [CPD:C00043];
beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-
galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide |
|---|
| Product |
UDP [CPD:C00015];
N-acetyl-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-
beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-
(11)-ceramide |
|---|
| Cofactor |
Manganese [CPD:C00034] |
|---|
| Comment |
Requires Mn2+. |
|---|
| Pathway |
PATH: ec00601 Glycosphingolipid biosynthesis - lacto and neolacto
series
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6238026]
Basu M, Basu S.
Biosynthesis in vitro of Ii core glycosphingolipids from
neolactotetraosylceramide by beta 1-3- and beta
1-6-N-acetylglucosaminyltransferases from mouse T-lymphoma.
J. Biol. Chem. 259 (1984) 12557-62.
Mus musculus [GN:mmu] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.4.1.163
IUBMB Enzyme Nomenclature: 2.4.1.163
ExPASy - ENZYME nomenclature database: 2.4.1.163
BRENDA, the Enzyme Database: 2.4.1.163
CAS: 85638-39-7 |
|---|
