KEGG   ENZYME: 2.4.1.184Help
Entry
EC 2.4.1.184                Enzyme                                 

Name galactolipid galactosyltransferase;
galactolipid-galactolipid galactosyltransferase;
galactolipid:galactolipid galactosyltransferase;
interlipid galactosyltransferase;
GGGT;
DGDG synthase (ambiguous);
digalactosyldiacylglycerol synthase (ambiguous);
3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-
galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:3-(beta-D-galactosyl)-1
,2-diacyl-sn-glycerol beta-D-galactosyltransferase
Reaction(IUBMB) 2 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol =
3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-
glycerol + 1,2-diacyl-sn-glycerol [RN:R04472]
Reaction(KEGG) R04472
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Substrate 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol [CPD:C03692]
Product 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-
glycerol [CPD:C06037];
1,2-diacyl-sn-glycerol [CPD:C00641]
Comment By further transfers of galactosyl residues to the
digalactosyldiacylglycerol, trigalactosyldiacylglycerol and
tetragalactosyldiacylglycerol are also formed. This enzyme was
originally thought to be the major enzyme involved in the production
of digalactosyldiacylglycerol in plants as it masked the effect of
the true enzyme (EC 2.4.1.241, digalactosyldiacylglycerol synthase)
[4,5]. Its activity is localized to chloroplast envelope membranes,
but it does not contribute to net galactolipid synthesis in plants
[4].
Pathway PATH: ec00561  Glycerolipid metabolism
PATH: ec01100  Metabolic pathways
Reference
  Authors
  Title

  Journal
1
Dorne, A.-J., Block, M.A., Joyard, J. and Douce, R.
The galactolipid-galactolipid galactosyltransferase is located on
the outer surface of the outer-membrane of the chloroplast envelope.
FEBS Lett. 145 (1982) 30-34.
Reference
  Authors

  Title

  Journal
2
Heemskerk, J.W.M., Wintermans, J.F.G.M., Joyard, J., Block, M.A.,
Dorne, A.-J. and Douce, R.
Localization of galactolipid:galactolipid galactosyltransferase and
acyltransferase in outer envelope membrane of spinach chloroplasts.
Biochim. Biophys. Acta 877 (1986) 281-289.
Reference
  Authors
  Title

  Journal
3
Heemskerk, J.W.M., Jacobs, F.H.H. and Wintermans, J.F.G.M.
UDPgalactose-independent synthesis of monogalactosyldiacylglycerol.
An enzymatic activity of the spinach chloroplast envelope.
Biochim. Biophys. Acta 961 (1988) 38-47.
Reference
  Authors
  Title


  Journal
  Organism
4  [PMID:14600212]
Kelly AA, Froehlich JE, Dormann P.
Disruption of the two digalactosyldiacylglycerol synthase genes DGD1
and DGD2 in Arabidopsis reveals the existence of an additional
enzyme of galactolipid synthesis.
Plant. Cell. 15 (2003) 2694-706.
Arabidopsis thaliana [GN:ath]
Reference
  Authors
  Title

  Journal
  Organism
5  [PMID:15590685]
Benning C, Ohta H.
Three enzyme systems for galactoglycerolipid biosynthesis are
coordinately regulated in plants.
J. Biol. Chem. 280 (2005) 2397-400.
Arabidopsis sp.
Other DBs ExplorEnz - The Enzyme Database: 2.4.1.184
IUBMB Enzyme Nomenclature: 2.4.1.184
ExPASy - ENZYME nomenclature database: 2.4.1.184
BRENDA, the Enzyme Database: 2.4.1.184
CAS: 66676-74-2

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