KEGG   ENZYME: 2.4.1.44Help
Entry
EC 2.4.1.44                 Enzyme                                 
Name
lipopolysaccharide 3-alpha-galactosyltransferase;
UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase;
UDP-galactose:polysaccharide galactosyltransferase;
uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase;
uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase;
UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase
Reaction(IUBMB)
UDP-alpha-D-galactose + lipopolysaccharide = UDP + 3-alpha-D-galactosyl-[lipopolysaccharide glucose] [RN:R01997]
Reaction(KEGG)
Substrate
UDP-alpha-D-galactose [CPD:C00052];
lipopolysaccharide [CPD:C00338]
Product
UDP [CPD:C00015];
3-alpha-D-galactosyl-[lipopolysaccharide glucose] [CPD:C04473]
Comment
Transfers alpha-D-galactosyl residues to D-glucose in the partially completed core of lipopolysaccharide [cf. EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)].
Pathway
Lipopolysaccharide biosynthesis
Metabolic pathways
Orthology
K03278  
UDP-D-galactose:(glucosyl)LPS alpha-1,3-D-galactosyltransferase
Genes
STY: 
STY4077(waaI)
STT: 
t3801(waaI)
SEX: 
STM: 
STM3718(rfaI)
SEO: 
SEV: 
SEY: 
SEM: 
SEJ: 
SEB: 
SEF: 
UMN798_4038(rfaI)
SPT: 
SPA3570(waaI)
SEK: 
SSPA3333
SPQ: 
SPAB_04615
SEI: 
SPC_3800(waaI)
SEC: 
SC3641(rfaI)
SEH: 
SeHA_C4043
SHB: 
SU5_04195
SEE: 
SNSL254_A3998
SEW: 
SeSA_A3917
SEA: 
SeAg_B3936
SED: 
SeD_A4105
SEG: 
SG3713(rfaI)
SEL: 
SPUL_3846(rfaI)
SET: 
SEN3540(rfaI)
SES: 
SARI_03923
SBG: 
SBG_3300(waaI)
 » show all
Taxonomy
Reference
1  [PMID:4898284]
  Authors
Endo A, Rothfield L.
  Title
Studies of a phospholipid-requiring bacterial enzyme. I. Purification and properties of uridine diphosphate galactose: lipopolysaccharide alpha-3-galactosyl transferase.
  Journal
Biochemistry. 8 (1969) 3500-7.
  Organism
Salmonella typhimurium
Reference
2  [PMID:6403519]
  Authors
Wollin R, Creeger ES, Rothfield LI, Stocker BA, Lindberg AA.
  Title
Salmonella typhimurium mutants defective in UDP-D-galactose:lipopolysaccharide alpha 1,6-D-galactosyltransferase. Structural, immunochemical, and enzymologic studies of rfaB mutants.
  Journal
J. Biol. Chem. 258 (1983) 3769-74.
  Organism
Salmonella typhimurium
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9073-98-7
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