KEGG   ENZYME: 2.4.1.46Help
Entry
EC 2.4.1.46                 Enzyme                                 

Name monogalactosyldiacylglycerol synthase;
uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase;
UDP-galactose:diacylglycerol galactosyltransferase;
MGDG synthase;
UDP galactose-1,2-diacylglycerol galactosyltransferase;
UDP-galactose-diacylglyceride galactosyltransferase;
UDP-galactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase;
1beta-MGDG;
1,2-diacylglycerol 3-beta-galactosyltransferase
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase
Reaction(IUBMB) UDP-galactose + 1,2-diacyl-sn-glycerol = UDP +
3-beta-D-galactosyl-1,2-diacyl-sn-glycerol [RN:R02691]
Reaction(KEGG) R02691
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Substrate UDP-galactose [CPD:C00052];
1,2-diacyl-sn-glycerol [CPD:C00641]
Product UDP [CPD:C00015];
3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
Comment This enzyme adds only one galactosyl group to the diacylglycerol; EC
2.4.1.241, digalactosyldiacylglycerol synthase, adds a galactosyl
group to the product of the above reaction. There are three isoforms
in Arabidopsis that can be divided into two types, A-type (MGD1) and
B-type (MGD2 and MGD3). MGD1 is the isoform responsible for the bulk
of monogalactosyldiacylglycerol (MGDG) synthesis in Arabidopsis [4].
Pathway PATH: ec00561  Glycerolipid metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K03715  1,2-diacylglycerol 3-beta-galactosyltransferase
Genes ATH: AT2G11810(MGDC) AT4G31780(MGD1) AT5G20410(MGD2)
POP: POPTR_562015 POPTR_578871 POPTR_811547
RCU: RCOM_0003390 RCOM_0920510
VVI: 100247378 100248939
OSA: 4345212(Os08g0299400) 4347099(Os09g0423600)
SBI: SORBI_02g025070(SORBIDRAFT_02g025070)
     SORBI_04g036240(SORBIDRAFT_04g036240)
     SORBI_07g027910(SORBIDRAFT_07g027910)
ZMA: 100274282 100281388(si660066d07)
PPP: PHYPADRAFT_105339 PHYPADRAFT_117530
OLU: OSTLU_119506(MgdA)
AJS: Ajs_1204
CTH: Cthe_2414
SUS: Acid_2769 Acid_4334
Taxonomy
Reference
  Authors
  Title


  Journal
  Organism
1  [PMID:4838219]
Veerkamp JH.
Biochemical changes in Bifidobacterium bifidum var. pennsylvanicus
after cell-wall inhibition. VI. Biosynthesis of the
galactosyldiglycerides.
Biochim. Biophys. Acta. 348 (1974) 23-34.
Bifidobacterium bifidum
Reference
  Authors
  Title


  Journal
  Organism
2  [PMID:5681471]
Wenger DA, Petitpas JW, Pieringer RA.
The metabolism of glyceride glycolipids. II. Biosynthesis of
monogalactosyl diglyceride from uridine diphosphate galactose and
diglyceride in brain.
Biochemistry. 7 (1968) 3700-7.
Rattus norvegicus [GN:rno]
Reference
  Authors

  Title


  Journal
  Organism
3  [PMID:10518794]
Miege C, Marechal E, Shimojima M, Awai K, Block MA, Ohta H, Takamiya
K, Douce R, Joyard J.
Biochemical and topological properties of type A MGDG synthase, a
spinach chloroplast envelope enzyme catalyzing the synthesis of both
prokaryotic and eukaryotic MGDG.
Eur. J. Biochem. 265 (1999) 990-1001.
Arabidopsis thaliana [GN:ath], Cucumis sativa, Spinacia oleracea
Reference
  Authors
  Title

  Journal
  Organism
4  [PMID:15590685]
Benning C, Ohta H.
Three enzyme systems for galactoglycerolipid biosynthesis are
coordinately regulated in plants.
J. Biol. Chem. 280 (2005) 2397-400.
Arabidopsis sp.
Other DBs ExplorEnz - The Enzyme Database: 2.4.1.46
IUBMB Enzyme Nomenclature: 2.4.1.46
ExPASy - ENZYME nomenclature database: 2.4.1.46
BRENDA, the Enzyme Database: 2.4.1.46
CAS: 37277-55-7

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