KEGG   ENZYME: 2.4.1.80Help
Entry
EC 2.4.1.80                 Enzyme                                 
Name ceramide glucosyltransferase;
UDP-glucose:ceramide glucosyltransferase;
ceramide:UDP-Glc glucosyltransferase;
uridine diphosphoglucose-ceramide glucosyltransferase;
ceramide:UDP-glucose glucosyltransferase;
glucosylceramide synthase
Class Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname UDP-glucose:N-acylsphingosine D-glucosyltransferase
Reaction(IUBMB) UDP-glucose + an N-acylsphingosine = UDP + a
D-glucosyl-N-acylsphingosine [RN:R01497 R06275]
Reaction(KEGG) R01497 R06275(G)
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Substrate UDP-glucose [CPD:C00029];
N-acylsphingosine [CPD:C00195]
Product UDP [CPD:C00015];
D-glucosyl-N-acylsphingosine [CPD:C01190]
Comment Sphingosine and dihydrosphingosine can also act as acceptors;
CDP-glucose can act as donor.
Pathway PATH: ec00600  Sphingolipid metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00720  ceramide glucosyltransferase
Genes HSA: 7357(UGCG)
PTR: 464660(UGCG)
MCC: 707875(UGCG)
MMU: 22234(Ugcg)
RNO: 83626(Ugcg)
CFA: 481666(UGCG)
BTA: 514357(UGCG)
SSC: 100152737
ECB: 100057611
MDO: 100018046
OAA: 100081601
GGA: 427335(UGCG)
TGU: 100222667
XLA: 399204(ugcg) 495444(ugcg-b)
XTR: 548887(ugcg)
DRE: 553944(ugcg)
BFO: BRAFLDRAFT_284635
CIN: 100181183
SPU: 591961
DME: Dmel_CG6437(GlcT-1)
DPO: Dpse_GA19592
DAN: Dana_GF13285
DER: Dere_GG22158
DPE: Dper_GL16974
DSE: Dsec_GM15879
DSI: Dsim_GD11642
DYA: Dyak_GE12238
DGR: Dgri_GH20547
DMO: Dmoj_GI18817
AGA: AgaP_AGAP012412
AAG: AaeL_AAEL000634
CQU: CpipJ_CPIJ019694
AME: 411552
NVI: 100117597(Glct-1)
TCA: 657299
API: 100167638
ISC: IscW_ISCW015936
CEL: F59G1.1(cgt-3)
CBR: CBG02537
BMY: Bm1_44040
SMM: Smp_157080
NVE: NEMVE_v1g128774
TAD: TRIADDRAFT_58861
LTH: KLTH0F15554g
DHA: DEHA0D19547g
PIC: PICST_34303(CGT1)
PPA: PAS_chr3_0357
LEL: LELG_04353
CTP: CTRG_00242
CDU: CD36_41900
YLI: YALI0B09669g
PAN: PODANSg8581
MGR: MGG_10668
FGR: FG05955.1
AFM: AFUA_5G09550
AOR: AO090020000582
ANG: An07g03380
AFV: AFLA_098440
PCS: Pc22g14340
NFI: NFIA_077760
URE: UREG_03833
SSL: SS1G_01525
BFU: BC1G_05569
CNE: CNH02280
CNB: CNBL2290
LBC: LACBIDRAFT_187066
MPR: MPER_07570
UMA: UM04496.1
MGL: MGL_0042
YPE: YPO1983
YPK: y2328
YPM: YP_1831(wcaG7)
YPA: YPA_1365
YPN: YPN_1463
YPP: YPDSF_1140
YPS: YPTB1976
YPI: YpsIP31758_2102
YPY: YPK_2212
YPB: YPTS_2031
XCC: XCC2437
XCB: XC_1675
XCA: xccb100_1729(ugcG)
XCV: XCV2767
XAC: XAC2568
AVN: Avin_20650
TTU: TERTU_3233
AFE: Lferr_1780
AFR: AFE_2121
REU: Reut_B4900
REH: H16_B2171
RME: Rmet_3407
CTI: RALTA_B1954
BMA: BMA0578 BMA3350
BMV: BMASAVP1_A3019
BML: BMA10229_A2073 BMA10229_A2853
BMN: BMA10247_1749 BMA10247_3328
BPS: BPSL0293 BPSL2399
BPM: BURPS1710b_0488 BURPS1710b_2860
BPL: BURPS1106A_0308 BURPS1106A_2797
BPD: BURPS668_0294 BURPS668_2738
BPR: GBP346_A0212(hpnI_1) GBP346_A2918(hpnI_2)
BTE: BTH_I0264 BTH_I1766
BVI: Bcep1808_1089 Bcep1808_4730
BUR: Bcep18194_A4282 Bcep18194_B0471
BCM: Bcenmc03_1146
BCJ: BCAL1050
BAM: Bamb_1049
BAC: BamMC406_1052 BamMC406_5080
BMU: Bmul_2134
BMJ: BMULJ_01110(ugcG)
BXE: Bxe_A2063 Bxe_A2068 Bxe_B0384
BPH: Bphy_1180 Bphy_7079
BPY: Bphyt_2195 Bphyt_2200
BGL: bglu_1g10000 bglu_2g03670
GSU: GSU0697
GME: Gmet_2815
GUR: Gura_1031
GLO: Glov_3180
GBM: Gbem_3357
GEO: Geob_3659
GEM: GM21_0888
PPD: Ppro_0563
DMA: DMR_03220
AFW: Anae109_3633
ANK: AnaeK_0943
MXA: MXAN_4793
SCL: sce9238(ugcG)
MLO: mlr5650
ATU: Atu1808(ugcG)
ATC: AGR_C_3323
RHI: NGR_b14520
MEX: Mext_0714 Mext_3454
MEA: Mex_1p0541 Mex_1p3685
MDI: METDI0697 METDI4258
MRD: Mrad2831_0974 Mrad2831_3865
MET: M446_6338 M446_6606
MPO: Mpop_0687 Mpop_3653
MCH: Mchl_0727 Mchl_3763
MNO: Mnod_7153 Mnod_7359
BID: Bind_0451 Bind_3673
MSL: Msil_0130 Msil_3035
RSP: RSP_2152
RSH: Rsph17029_0826
RSQ: Rsph17025_0822
RSK: RSKD131_0463
ZMO: ZMO0972
ZMN: Za10_0329
GOX: GOX0615
GBE: GbCGDNIH1_2402
ACR: Acry_1835
GDI: GDI_0719
GDJ: Gdia_1291
APT: APA01_03950
MAG: amb3484
SSA: SSA_1324
ABA: Acid345_0723 Acid345_0724
ACA: ACP_0805 ACP_1042 ACP_2005
FNU: FN1845
LBA: Lebu_1741
STR: Sterm_3115
SYN: slr0813
TEL: tll0064
CYT: cce_0751
CYP: PCC8801_0746
CYC: PCC7424_3568
CYN: Cyan7425_1602 Cyan7425_5069
CYH: Cyan8802_0775
AMR: AM1_5794
HAU: Haur_0401
TYE: THEYE_A1783
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:4631392]
Basu S, Kaufman B, Roseman S.
Enzymatic synthesis of glucocerebroside by a glucosyltransferase
from embryonic chicken brain.
J. Biol. Chem. 248 (1973) 1388-94.
Rattus norvegicus [GN:rno]
Other DBs ExplorEnz - The Enzyme Database: 2.4.1.80
IUBMB Enzyme Nomenclature: 2.4.1.80
ExPASy - ENZYME nomenclature database: 2.4.1.80
BRENDA, the Enzyme Database: 2.4.1.80
CAS: 37237-44-8
DBGET integrated database retrieval system